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13F-HR filed by ORBIMED ADVISORS LLC

ORBIMED ADVISORS LLC filed this 13F-HR for the quarter ended 2020-06-30, filed 2020-08-14, with 135 holding rows worth $7,102,993,000.

Accession
0001172661-20-001859
Filed
2020-08-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q2 2020

A holdings report, 135 entries on the cover page, a total value of $7,102,993,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $7,102,993,000 with VALUE read as thousands by filing date, 13F file number 028-06774. The quarter's positions are built on this report. The resolved quarter.

Other managers

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
SPRINGWORKS THERAPEUTICS INC85205L107COM7,406,307$311,065,000thousands by filing date
TRICIDA INC89610F101COM9,614,280$264,200,000thousands by filing date
ALEXION PHARMACEUTICALS INC015351109COM2,156,000$241,989,000thousands by filing date
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR1,562,986$231,166,000thousands by filing date
PREVAIL THERAPEUTICS INC74140Y101COM13,822,463$205,955,000thousands by filing date
Merck & Co.,Inc.58933Y105COM2,589,100$200,215,000thousands by filing date
Vertex Pharmaceuticals Incorporated92532F100COM666,100$193,375,000thousands by filing date
BIOGEN INC COM09062X103Stock715,900$191,539,000thousands by filing date
PASSAGE BIO INC702712100COM6,962,899$190,296,000thousands by filing date
IOVANCE BIOTHERAPEUTICS INC462260100COM6,645,100$182,408,000thousands by filing date
TURNING PT THERAPEUTICS90041T108COM2,745,327$177,321,000thousands by filing date
Boston Scientific Corporation101137107COM4,847,300$170,189,000thousands by filing date
Bristol-Myers Squibb Company110122108COM2,882,200$169,473,000thousands by filing date
NATERA INC COM632307104Stock3,240,514$161,572,000thousands by filing date
HORIZON THERAPEUTICS PLCG46188101SHS2,867,910$159,398,000thousands by filing date
MIRATI THERAPEUTICS INC60468T105COM1,324,100$151,172,000thousands by filing date
ALECTOR INC014442107COMMON STOCK5,975,322$146,037,000thousands by filing date
NEUROCRINE BIOSCIENCES INC64125C109COM1,185,915$144,682,000thousands by filing date
ARCUTIS BIOTHERAPEUTICS INC03969K108COM4,673,850$141,337,000thousands by filing date
BURNING ROCK BIOTECH LTD12233L107SPONSORED ADS4,746,071$128,191,000thousands by filing date
HUMANA INC COM444859102Stock280,300$108,686,000thousands by filing date
REPARE THERAPEUTICS INC760273102COM3,426,325$106,285,000thousands by filing date
ORIC PHARMACEUTICALS INC68622P109COM2,921,967$98,558,000thousands by filing date
AGIOS PHARMACEUTICALS INC00847X104COM1,728,421$92,436,000thousands by filing date
DEXCOM INC COM252131107Stock226,400$91,783,000thousands by filing date
SAREPTA THERAPEUTICS INC803607100COM559,649$89,734,000thousands by filing date
CENTENE CORP DEL COM15135B101Stock1,335,700$84,884,000thousands by filing date
Cigna Corporation125523100COM439,700$82,510,000thousands by filing date
89BIO INC282559103COM4,004,442$79,809,000thousands by filing date
IMARA INC45249V107COM2,719,902$75,151,000thousands by filing date
Adverum Biotechnologies, Inc.00773U108Common Stock3,290,744$68,711,000thousands by filing date
DECIPHERA PHARMACEUTICALS IN24344T101COM1,125,700$67,227,000thousands by filing date
Intuitive Surgical,Inc.46120E602COM112,800$64,277,000thousands by filing date
KEROS THERAPEUTICS INC COM492327101Stock1,679,417$62,995,000thousands by filing date
EHEALTH INC28238P109COM638,558$62,732,000thousands by filing date
NEXTCURE INC65343E108COM2,711,013$58,124,000thousands by filing date
EXELIXIS INC COM30161Q104Stock2,404,100$57,073,000thousands by filing date
KALA BIO INC COM483119103Stock5,402,730$56,783,000thousands by filing date
FUSION PHARMACEUTICALS INC36118A100COM3,224,770$56,337,000thousands by filing date
ATRICURE INC04963C209COM1,228,189$55,207,000thousands by filing date
ATHENEX INC04685N103COM4,009,346$55,169,000thousands by filing date
LOGICBIO THERAPEUTICS INC54142F102COM6,466,783$54,709,000thousands by filing date
THERAVANCE BIOPHARMA INCG8807B106COM2,554,470$53,618,000thousands by filing date
BELLUS HEALTH INC NEW07987C204COM5,137,216$53,001,000thousands by filing date
CRISPR THERAPEUTICS AG NAMEN AKTH17182108Stock697,524$51,261,000thousands by filing date
CRINETICS PHARMACEUTICALS INC COM22663K107Stock2,753,567$48,242,000thousands by filing date
GLAUKOS CORP COM377322102Stock1,211,000$46,527,000thousands by filing date
MEIRAGTX HOLDINGS PLCG59665102COMMON STOCK3,713,820$46,497,000thousands by filing date
AbbVie,Inc.00287Y109COM464,000$45,556,000thousands by filing date
Mersana Therapeutics Inc59045L106Common Stock1,910,008$44,694,000thousands by filing date
Applied Therapeutics Inc03828A101Common Stock1,217,678$44,019,000thousands by filing date
UNIQURE NVN90064101SHS969,079$43,667,000thousands by filing date
Thermo Fisher Scientific Inc.883556102COM110,300$39,966,000thousands by filing date
TELA BIO INC872381108COM3,027,542$39,237,000thousands by filing date
AEGLEA BIOTHERAPEUTICS INC00773J103COM4,015,524$37,144,000thousands by filing date
PROTHENA CORP PLC SHSG72800108Stock3,544,475$37,075,000thousands by filing date
EDWARDS LIFESCIENCES CORP COM28176E108Stock530,400$36,656,000thousands by filing date
ALPINE IMMUNE SCIENCES INC02083G100COM3,670,955$35,645,000thousands by filing date
SCPHARMACEUTICALS INC810648105COM4,797,148$35,307,000thousands by filing date
NANOSTRING TECHNOLOGIES INC63009R109COM1,192,400$34,997,000thousands by filing date
ACADIA HEALTHCARE COMPANY INC COM00404A109Stock1,380,160$34,670,000thousands by filing date
SELECTQUOTE INC816307300COM1,255,000$31,789,000thousands by filing date
XENON PHARMACEUTICALS INC COM98420N105Stock2,497,917$31,324,000thousands by filing date
HARPOON THERAPEUTICS INC41358P106COM1,835,704$30,473,000thousands by filing date
INSPIRE MED SYS INC COM457730109Stock347,000$30,196,000thousands by filing date
VAXCYTE INC COM92243G108Stock850,000$26,869,000thousands by filing date
IMMUNOMEDICS INC452907108COM757,900$26,860,000thousands by filing date
SINOVAC BIOTECH LTDP8696W104SHS2,839,500$25,500,000thousands by filing date
IQVIA HLDGS INC COM46266C105Stock175,000$24,829,000thousands by filing date
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS881624209ADR1,935,200$23,861,000thousands by filing date
FLEXION THERAPEUTICS INC33938J106COM1,684,000$22,145,000thousands by filing date
SI BONE INC825704109COM1,381,300$22,018,000thousands by filing date
NOVO-NORDISK A S ADR670100205ADR330,000$21,608,000thousands by filing date
Amgen Inc.031162100COM91,500$21,581,000thousands by filing date
ZYMEWORKS INC98985W102COM582,302$21,004,000thousands by filing date
ALCON AG ORD SHSH01301128Stock351,380$20,168,000thousands by filing date
BENEFYTT TECHNOLOGIES INC08182C106COM CL A962,900$19,701,000thousands by filing date
AURINIA PHARMACEUTICALS INC COM05156V102Stock1,196,347$19,441,000thousands by filing date
REGENERON PHARMACEUTICALS COM75886F107Stock30,900$19,271,000thousands by filing date
CORVUS PHARMACEUTICALS INC221015100COM6,767,584$18,408,000thousands by filing date
SIERRA ONCOLOGY INC82640U404CMN1,477,320$17,876,000thousands by filing date
IVERIC BIO INC46583P102COM3,250,000$16,575,000thousands by filing date
VERRICA PHARMACEUTICALS INC92511W108COM1,479,733$16,292,000thousands by filing date
SYNDAX PHARMACEUTICALS INC87164F105COM1,094,100$16,215,000thousands by filing date
ObsEva SAH5861P103COM2,605,531$15,347,000thousands by filing date
Gilead Sciences,Inc.375558103COM192,200$14,788,000thousands by filing date
9 METERS BIOPHARMA INC654405109COM25,716,755$14,591,000thousands by filing date
FORTE BIOSCIENCES INC34962G109COM950,316$13,856,000thousands by filing date
TECTONIC THERAPEUTIC INC COM05455M100Stock793,712$13,850,000thousands by filing date
BIOMX INC09090D103COM2,313,489$12,770,000thousands by filing date
ACCELERON PHARMA INC00434H108COM127,500$12,147,000thousands by filing date
LARIMAR THERAPEUTICS INC517125100COM933,960$12,001,000thousands by filing date
STANDARD BIOTOOLS INC34385P108COM2,907,100$11,657,000thousands by filing date
ALEXION PHARMACEUTICALS INC015351109COM100,000$11,224,000thousands by filing datecall
ARCTURUS THERAPEUTICS HLDGS03969T109COM239,186$11,180,000thousands by filing date
CTI BIOPHARMA CORP12648L601COM9,520,600$11,044,000thousands by filing date
GENMARK DIAGNOSTICS INC372309104COM732,000$10,768,000thousands by filing date
RESTORBIO INC76133L103COM4,830,387$10,385,000thousands by filing date
X4 Pharmaceuticals, Inc.98420X103COM1,086,493$10,126,000thousands by filing date
AbbVie,Inc.00287Y109COM100,000$9,818,000thousands by filing datecall
TRILLIUM THERAPEUTICS INC COM NEW89620X506Stock1,211,000$9,797,000thousands by filing date
HERON THERAPEUTICS INC427746102COM660,420$9,715,000thousands by filing date
ESSA PHARMA INC29668H708COM NEW1,471,853$9,125,000thousands by filing date
PROGYNY INC COM74340E103Stock341,004$8,801,000thousands by filing date
IMMUNOVANT INC45258J102COM354,575$8,634,000thousands by filing date
ANAPTYSBIO INC032724106COM375,800$8,395,000thousands by filing date
XTANT MED HLDGS INC98420P308COM NEW9,248,678$8,324,000thousands by filing date
10X GENOMICS INC CL A COM88025U109Stock92,700$8,279,000thousands by filing date
CELLDEX THERAPEUTICS INC NEW15117B202COM NEW625,000$8,125,000thousands by filing date
ROCKET PHARMACEUTICALS INC77313F106COM382,400$8,004,000thousands by filing date
AKOUOS INC00973J101COM315,000$7,088,000thousands by filing date
AERPIO PHARMACEUTICALS INC00810B105COM5,193,946$6,492,000thousands by filing date
APTOSE BIOSCIENCES INC COM03835T200Stock950,841$6,000,000thousands by filing date
SELECTA BIOSCIENCES INC816212104COM2,093,869$5,947,000thousands by filing date
IGM BIOSCIENCES INC449585108COM80,760$5,895,000thousands by filing date
VERONA PHARMA PLC925050106SPONSORED ADS1,250,396$5,852,000thousands by filing date
AVIDITY BIOSCIENCES INC COM05370A108Stock200,000$5,652,000thousands by filing date
ARCUS BIOSCIENCES INC03969F109COM220,350$5,451,000thousands by filing date
AGIOS PHARMACEUTICALS INC00847X104COM100,000$5,348,000thousands by filing datecall
HEALTH CATALYST INC42225T107COM179,598$5,239,000thousands by filing date
CALLIDITAS THERAPEUTICS AB SPONSERED13124Q106ADS225,000$5,220,000thousands by filing date
ARENA PHARMACEUTICALS INC040047607COM NEW66,700$4,199,000thousands by filing date
SYNLOGIC INC87166L100COM2,029,996$4,121,000thousands by filing date
KITOV PHARMA LTD SPONSORED ADS49803V107Stock3,461,983$3,843,000thousands by filing date
NABRIVA THERAPEUTICS PLCG63637105SHS4,644,600$3,133,000thousands by filing date
Inflarx NvN44821101COM678,525$3,114,000thousands by filing date
ARROWHEAD PHARMACEUTICALS IN04280A100COM68,100$2,941,000thousands by filing date
CORBUS PHARMACEUTICALS HLDGS21833P103COM350,000$2,937,000thousands by filing dateput
INTELLIA THERAPEUTICS INC45826J105COM137,100$2,882,000thousands by filing date
CURIS INC231269200COM1,241,494$1,502,000thousands by filing date
NOVUS THERAPEUTICS INC67011N105COM3,183,314$1,459,000thousands by filing date
BRISTOL-MYERS SQUIBB CO110122157RIGHT 99/99/9999350,000$1,253,000thousands by filing date
MENLO THERAPEUTICS INC586858102COM593,883$1,027,000thousands by filing date
ARVINAS INC04335A105COM29,400$986,000thousands by filing date
NULL09071M205NULL69,240$118,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001172661-20-001859this filing2020-08-14acceptance time not in the bulk data set