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13F-HR filed by ORBIMED ADVISORS LLC

ORBIMED ADVISORS LLC filed this 13F-HR for the quarter ended 2017-03-31, filed 2017-05-15, with 136 holding rows worth $8,822,204,000.

Accession
0001172661-17-001216
Filed
2017-05-15
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q1 2017

A holdings report, 136 entries on the cover page, a total value of $8,822,204,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $8,822,204,000 with VALUE read as thousands by filing date, 13F file number 028-06774. The quarter's positions are built on this report. The resolved quarter.

Other managers

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
ALEXION PHARMACEUTICALS INC015351109COM3,710,986$449,920,000thousands by filing date
BIOGEN INC COM09062X103Stock1,436,900$392,877,000thousands by filing date
CELGENE CORP151020104COM3,132,177$389,737,000thousands by filing date
Boston Scientific Corporation101137107COM15,311,400$380,795,000thousands by filing date
Merck & Co.,Inc.58933Y105COM5,714,900$363,125,000thousands by filing date
Eli Lilly and Company532457108COM3,330,200$280,103,000thousands by filing date
WRIGHT MED GROUP N VN96617118ORD SHS8,946,234$278,407,000thousands by filing date
INCYTE CORP COM45337C102Stock1,973,597$263,811,000thousands by filing date
Vertex Pharmaceuticals Incorporated92532F100COM2,169,200$237,202,000thousands by filing date
Amgen Inc.031162100COM1,438,300$235,982,000thousands by filing date
AGILENT TECHNOLOGIES INC COM00846U101Stock3,629,900$191,913,000thousands by filing date
Pfizer Inc.717081103COM5,406,100$184,943,000thousands by filing date
EDWARDS LIFESCIENCES CORP COM28176E108Stock1,839,300$173,023,000thousands by filing date
AETNA INC NEW00817Y108COM1,312,400$167,397,000thousands by filing date
SHIRE PLC82481R106COMMON STOCK-FO897,451$156,363,000thousands by filing date
HCA Healthcare Inc40412C101COM1,745,000$155,288,000thousands by filing date
HUMANA INC COM444859102Stock742,300$153,018,000thousands by filing date
REGENERON PHARMACEUTICALS COM75886F107Stock378,170$146,545,000thousands by filing date
Elevance Health, Inc.036752103COM862,600$142,657,000thousands by filing date
AbbVie,Inc.00287Y109COM2,080,000$135,533,000thousands by filing date
ARRAY BIOPHARMA INC COM04269X105Stock14,182,900$126,795,000thousands by filing date
IRONWOOD PHARMACEUTICALS INC46333X108COMMON STOCK7,241,300$123,537,000thousands by filing date
CENTENE CORP DEL COM15135B101Stock1,655,700$117,985,000thousands by filing date
INTERCEPT PHARMACEUTICALS IN45845P108COM1,037,000$117,285,000thousands by filing date
ALLERGAN PLCG0177J108SHS477,390$114,058,000thousands by filing date
BIOMARIN PHARMACEUTICAL INC09061G101COM1,274,100$111,840,000thousands by filing date
CORVUS PHARMACEUTICALS INC221015100COM5,379,349$111,729,000thousands by filing date
Johnson & Johnson478160104COM884,600$110,177,000thousands by filing date
Bristol-Myers Squibb Company110122108COM1,911,000$103,920,000thousands by filing date
SYNERGY PHARMACEUTICALS DEL871639308COM NEW21,153,343$98,575,000thousands by filing date
TENET HEALTHCARE CORP COM NEW88033G407Stock5,352,000$94,784,000thousands by filing date
GLAUKOS CORP COM377322102Stock1,741,700$89,349,000thousands by filing date
INSMED INC COM PAR $.01457669307Stock4,810,905$84,239,000thousands by filing date
PUMA BIOTECHNOLOGY INC74587V107COMMON STOCK2,245,925$83,548,000thousands by filing date
Thermo Fisher Scientific Inc.883556102COM534,200$82,053,000thousands by filing date
AUDENTES THERAPEUTICS INC.05070R104Common Stock4,801,638$81,820,000thousands by filing date
Viewra, Inc92672L107COM9,458,567$80,492,000thousands by filing date
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR2,717,315$76,085,000thousands by filing date
MAGELLAN HEALTH SERVICES INC559079207COM NEW1,088,727$75,177,000thousands by filing date
ALLERGAN PLCG0177J116PFD CONV SER A88,200$74,832,000thousands by filing date
LOXO ONCOLOGY INC548862101COM1,728,000$72,714,000thousands by filing date
AERIE PHARMACEUTICALS INC00771V108COM1,496,000$67,844,000thousands by filing date
Mallinckrodt PlcG5785G107SHS1,472,700$65,638,000thousands by filing date
INSYS THERAPEUTICS INC45824V209COMMON STOCK6,071,440$63,811,000thousands by filing date
Medtronic PlcG5960L103COM766,600$61,757,000thousands by filing date
GW PHARMACEUTICALS PLC36197T103ADS475,900$57,555,000thousands by filing date
EAGLE PHARMACEUTICALS INC269796108COM671,000$55,653,000thousands by filing date
ACHILLION PHARMACEUTICALS IN00448Q201COM13,107,200$55,181,000thousands by filing date
ILLUMINA INC452327109COM321,900$54,929,000thousands by filing date
Gilead Sciences,Inc.375558103COM800,900$54,397,000thousands by filing date
JAZZ PHARMACEUTICALS PLC SHS USDG50871105Stock371,400$53,901,000thousands by filing date
MYLAN NVN59465109SHS EURO1,300,000$50,687,000thousands by filing date
UnitedHealth Group Inc91324P102COM296,400$48,613,000thousands by filing date
NEWLINK GENETICS CORP651511107COM1,991,700$48,000,000thousands by filing date
IMMUNOMEDICS INC452907AK4NOTE 4.750 2/130,000,000$42,261,000thousands by filing dateprincipal
Stryker Corporation863667101COM316,300$41,641,000thousands by filing date
ACADIA PHARMACEUTICALS INC004225108COM1,169,000$40,190,000thousands by filing date
GLOBAL BLOOD THERAPEUTICS USD37890U108COM1,084,500$39,964,000thousands by filing date
Intuitive Surgical,Inc.46120E602COM50,400$38,630,000thousands by filing date
THE COOPER COMPANIES216648402COM NEW190,800$38,139,000thousands by filing date
INTELLIA THERAPEUTICS INC45826J105COM2,662,180$37,510,000thousands by filing date
DERMIRA INC24983L104COM1,023,673$34,917,000thousands by filing date
BEONE MEDICINES LTD SPONSORED ADS07725L102ADR903,700$33,084,000thousands by filing date
ASSEMBLY BIOSCIENCES INC045396108COM1,257,300$32,049,000thousands by filing date
SAREPTA THERAPEUTICS INC803607100COM1,054,300$31,207,000thousands by filing date
MOMENTA PHARMACEUTICALS INC60877T100COM2,109,068$28,156,000thousands by filing date
SELECT MED HLDGS CORP81619Q105COM2,086,300$27,852,000thousands by filing date
RADIUS HEALTH INC750469207COM NEW704,100$27,213,000thousands by filing date
ObsEva SAH5861P103COM2,605,531$27,124,000thousands by filing date
SELECTA BIOSCIENCES INC816212104COM1,842,797$26,389,000thousands by filing date
BLUEBIRD BIO INC09609G100COM283,800$25,797,000thousands by filing date
Lion Biotechnologies53619R102COM3,382,900$25,203,000thousands by filing date
LAKEFRONT BIOTHERAPEUTICS NV36315X101SPON ADR283,500$24,435,000thousands by filing date
IMMUNOGEN INC45253H101COMMON STOCK6,095,647$23,590,000thousands by filing date
COHERUS ONCOLOGY INC19249H103COM1,084,400$22,935,000thousands by filing date
OTONOMY INC68906L105COM1,850,094$22,664,000thousands by filing date
EHEALTH INC28238P109COM1,820,000$21,913,000thousands by filing date
NABRIVA THERAPEUTICS AG62957M104SPONSORED ADR1,677,940$20,135,000thousands by filing date
XENCOR INC98401F105COMMON STOCK840,237$20,098,000thousands by filing date
NEUROCRINE BIOSCIENCES INC64125C109COM441,341$19,110,000thousands by filing date
PIERIS PHARMACEUTICALS INC720795103COM7,259,620$18,875,000thousands by filing date
DBV TECHNOLOGIES S A23306J101ADR512,900$18,064,000thousands by filing date
STEADYMED LTDM84920103SHS3,072,196$17,819,000thousands by filing date
SINOVAC BIOTECH LTDP8696W104SHS2,667,500$15,285,000thousands by filing date
BARD C R INC067383109COM58,000$14,415,000thousands by filing date
EXACT SCIENCES CORP COM30063P105Stock602,900$14,240,000thousands by filing date
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS881624209ADR412,600$13,240,000thousands by filing date
AURINIA PHARMACEUTICALS INC COM05156V102Stock1,797,400$13,193,000thousands by filing date
AEGERION PHARMACEUTICALS INC00767EAB8NOTE 2.000 8/115,000,000$12,317,000thousands by filing dateprincipal
PROQR THERAPEUTICS NVN71542109SHS EURO2,305,446$11,527,000thousands by filing date
NATERA INC COM632307104Stock1,276,190$11,320,000thousands by filing date
AEGLEA BIOTHERAPEUTICS INC00773J103COM1,469,524$10,948,000thousands by filing date
Bristol-Myers Squibb Company110122108COM200,000$10,876,000thousands by filing dateput
WRIGHT MED GROUP N VN96617126RIGHT 03/01/20196,900,000$10,558,000thousands by filing date
ADAPTIMMUNE THERAPEUTICS PLC00653A107SPONDS ADR1,914,660$10,550,000thousands by filing date
INFINITY PHARMACEUTICALS INC45665G303COM3,250,300$10,498,000thousands by filing date
STANDARD BIOTOOLS INC34385P108COM1,746,100$9,935,000thousands by filing date
HERON THERAPEUTICS INC427746102COM650,000$9,750,000thousands by filing date
DIMENSION THERAPEUTICS INC25433V105COM5,397,698$9,446,000thousands by filing date
NUVASIVE INC670704105COM123,500$9,223,000thousands by filing date
ALKERMES PLCG01767105SHS145,000$8,483,000thousands by filing date
CELLECTIS ADS15117K103COM350,000$8,400,000thousands by filing date
CRISPR THERAPEUTICS AG NAMEN AKTH17182108Stock372,191$8,103,000thousands by filing date
IMMUNOMEDICS INC452907108COM1,232,100$7,972,000thousands by filing date
WRIGHT MED GROUP N VN96617118ORD SHS250,000$7,780,000thousands by filing datecall
NEVRO CORP64157F103COM77,800$7,290,000thousands by filing date
TESARO INC881569107COM47,200$7,263,000thousands by filing date
STANDARD BIOTOOLS INC34385PAA6NOTE 2.750% 2/010,000,000$6,815,000thousands by filing dateprincipal
SYNDAX PHARMACEUTICALS INC87164F105COM484,800$6,651,000thousands by filing date
ALEXION PHARMACEUTICALS INC015351109COM50,000$6,062,000thousands by filing datecall
ZIMMER BIOMET HOLDINGS INC COM98956P102Stock49,000$5,983,000thousands by filing date
MINERVA NEUROSCIENCES INC COM NEW603380106Stock704,300$5,705,000thousands by filing date
SIERRA ONCOLOGY INC82640U107COM3,703,704$5,667,000thousands by filing date
Bristol-Myers Squibb Company110122108COM100,000$5,438,000thousands by filing datecall
REDHILL BIOPHARMA LTD757468103ADR564,900$5,417,000thousands by filing date
INVITAE CORP46185L103COM456,666$5,051,000thousands by filing date
NEWLINK GENETICS CORP651511107COM200,000$4,820,000thousands by filing datecall
AFFIMED N VN01045108COM2,018,900$4,643,000thousands by filing date
INOTEK PHARMACEUTICALS CORP45780VAB8NOTE 5.750% 8/07,000,000$4,433,000thousands by filing dateprincipal
SIENTRA INC82621J105COM522,257$4,397,000thousands by filing date
ALNYLAM PHARMACEUTICALS INC COM02043Q107Stock82,200$4,213,000thousands by filing date
ROKA BIOSCIENCE INC COM NEW775431208Stock893,470$3,181,000thousands by filing date
OREXIGEN THERAPEUTICS INC686164AC8NOTE 2.750%12/0 DELETED5,210,000$2,591,000thousands by filing dateprincipal
XENON PHARMACEUTICALS INC COM98420N105Stock634,812$2,539,000thousands by filing date
CLEARSIDE BIOMEDICAL INC185063104COM300,000$2,382,000thousands by filing date
VALEANT PHARMACEUTICALS INTL91911K102COM194,900$2,150,000thousands by filing date
AMARIN CORP PLC023111206SPONS ADR NEW350,000$1,120,000thousands by filing date
NOVELION THERAPEUTICS INC67001K202COM NEW100,000$1,074,000thousands by filing date
MARINUS PHARMACEUTICALS INC56854Q101COM567,600$1,005,000thousands by filing date
BIOLINERX LTD-SPONS ADR09071M106SPON1,038,600$998,000thousands by filing date
VANDA PHARMACEUTICALS INC921659108COM50,200$703,000thousands by filing date
BIOMARIN PHARMACEUTICAL INC09061GAF8NOTE 1.500%10/1500,000$593,000thousands by filing dateprincipal
BIOMARIN PHARMACEUTICAL INC09061GAE1NOTE 0.750%10/1500,000$567,000thousands by filing dateprincipal
ALIMERA SCIENCES INC016259103COM250,000$350,000thousands by filing date
XTNT98420P100Common475,439$296,000thousands by filing date
MEDIGUS LTD58471G201SPONSORD ADR NEW60,000$185,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001172661-17-001216this filing2017-05-15acceptance time not in the bulk data set