13F-HR filed by ORBIMED ADVISORS LLC
ORBIMED ADVISORS LLC filed this 13F-HR for the quarter ended 2016-03-31, filed 2016-05-16, with 141 holding rows worth $9,503,629,000.
- Accession
- 0001172661-16-003439
- Filer
- CIK 1055951
- Filed
- 2016-05-16
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q1 2016
A holdings report, 141 entries on the cover page, a total value of $9,503,629,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $9,503,629,000 with VALUE read as thousands by filing date, 13F file number 028-06774. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerORBIMED CAPITAL LLC028-10410
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| Bristol-Myers Squibb Company | 110122108 | COM | 7,624,900 | $487,079,000 | thousands by filing date | |
| HCA Healthcare Inc | 40412C101 | COM | 5,737,100 | $447,781,000 | thousands by filing date | |
| Amgen Inc. | 031162100 | COM | 2,876,000 | $431,199,000 | thousands by filing date | |
| Boston Scientific Corporation | 101137107 | COM | 22,479,700 | $422,843,000 | thousands by filing date | |
| AbbVie,Inc. | 00287Y109 | COM | 7,395,700 | $422,442,000 | thousands by filing date | |
| ALLERGAN PLC | G0177J108 | SHS | 1,572,715 | $421,535,000 | thousands by filing date | |
| BIOGEN INC COM | 09062X103 | Stock | 1,526,300 | $397,326,000 | thousands by filing date | |
| CELGENE CORP | 151020104 | COM | 3,774,077 | $377,747,000 | thousands by filing date | |
| Gilead Sciences,Inc. | 375558103 | COM | 3,019,200 | $277,344,000 | thousands by filing date | |
| ALEXION PHARMACEUTICALS INC | 015351109 | COM | 1,870,600 | $260,425,000 | thousands by filing date | |
| IMPAX LABORATORIES INC | 45256B101 | COM | 6,776,100 | $216,971,000 | thousands by filing date | |
| Thermo Fisher Scientific Inc. | 883556102 | COM | 1,435,000 | $203,182,000 | thousands by filing date | |
| INCYTE CORP COM | 45337C102 | Stock | 2,755,078 | $199,661,000 | thousands by filing date | |
| REGENERON PHARMACEUTICALS COM | 75886F107 | Stock | 533,000 | $192,115,000 | thousands by filing date | |
| Eli Lilly and Company | 532457108 | COM | 2,541,300 | $182,999,000 | thousands by filing date | |
| WELLCARE HEALTH PLANS INC | 94946T106 | COM | 1,903,300 | $176,531,000 | thousands by filing date | |
| Intuitive Surgical,Inc. | 46120E602 | COM | 276,800 | $166,371,000 | thousands by filing date | |
| EXPRESS SCRIPTS HLDG CO | 30219G108 | COM | 2,421,000 | $166,298,000 | thousands by filing date | |
| Vertex Pharmaceuticals Incorporated | 92532F100 | COM | 1,869,400 | $148,599,000 | thousands by filing date | |
| ILLUMINA INC | 452327109 | COM | 900,000 | $145,899,000 | thousands by filing date | |
| TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS | 881624209 | ADR | 2,696,000 | $144,263,000 | thousands by filing date | |
| INTERCEPT PHARMACEUTICALS IN | 45845P108 | COM | 1,120,000 | $143,886,000 | thousands by filing date | |
| AGILENT TECHNOLOGIES INC COM | 00846U101 | Stock | 3,495,000 | $139,276,000 | thousands by filing date | |
| WRIGHT MED GROUP N V | N96617118 | ORD SHS | 8,345,110 | $138,529,000 | thousands by filing date | |
| MAGELLAN HEALTH SERVICES INC | 559079207 | COM NEW | 1,909,000 | $129,678,000 | thousands by filing date | |
| IRONWOOD PHARMACEUTICALS INC | 46333X108 | COMMON STOCK | 11,550,400 | $126,361,000 | thousands by filing date | |
| THE COOPER COMPANIES | 216648402 | COM NEW | 795,900 | $122,545,000 | thousands by filing date | |
| Pfizer Inc. | 717081103 | COM | 4,122,000 | $122,176,000 | thousands by filing date | |
| NEUROCRINE BIOSCIENCES INC | 64125C109 | COM | 2,653,874 | $104,961,000 | thousands by filing date | |
| UnitedHealth Group Inc | 91324P102 | COM | 812,000 | $104,667,000 | thousands by filing date | |
| RELYPSA INC | 759531106 | Common Stock | 7,400,000 | $100,270,000 | thousands by filing date | |
| ALLERGAN PLC | G0177J116 | PFD CONV SER A | 104,200 | $95,774,000 | thousands by filing date | |
| ACHILLION PHARMACEUTICALS IN | 00448Q201 | COM | 11,519,700 | $88,932,000 | thousands by filing date | |
| OPHTHOTECH CORP | 683745103 | COM | 2,094,500 | $88,535,000 | thousands by filing date | |
| BIOMARIN PHARMACEUTICAL INC | 09061G101 | COM | 1,023,200 | $84,394,000 | thousands by filing date | |
| TESARO INC | 881569107 | COM | 1,912,000 | $84,185,000 | thousands by filing date | |
| PUMA BIOTECHNOLOGY INC | 74587V107 | COMMON STOCK | 2,753,425 | $80,868,000 | thousands by filing date | |
| Mallinckrodt Plc | G5785G107 | SHS | 1,309,000 | $80,216,000 | thousands by filing date | |
| CORVUS PHARMACEUTICALS INC | 221015100 | COM | 5,258,450 | $76,248,000 | thousands by filing date | |
| INSYS THERAPEUTICS INC | 45824V209 | COMMON STOCK | 4,557,740 | $72,878,000 | thousands by filing date | |
| NUVASIVE INC | 670704105 | COM | 1,487,000 | $72,343,000 | thousands by filing date | |
| HUMANA INC COM | 444859102 | Stock | 339,700 | $62,148,000 | thousands by filing date | |
| LOXO ONCOLOGY INC | 548862101 | COM | 2,175,857 | $59,488,000 | thousands by filing date | |
| Johnson & Johnson | 478160104 | COM | 531,800 | $57,541,000 | thousands by filing date | |
| IMMUNOGEN INC | 45253H101 | COMMON STOCK | 6,095,647 | $51,935,000 | thousands by filing date | |
| SHIRE PLC | 82481R106 | COMMON STOCK-FO | 300,371 | $51,634,000 | thousands by filing date | |
| SPDR SER TR | 78464A870 | S&P BIOTECH | 981,200 | $50,689,000 | thousands by filing date | |
| Medtronic Plc | G5960L103 | COM | 666,299 | $49,972,000 | thousands by filing date | |
| GLAUKOS CORP COM | 377322102 | Stock | 2,897,938 | $48,859,000 | thousands by filing date | |
| CIGNA CORPORATION | 125509109 | COM | 335,500 | $46,044,000 | thousands by filing date | |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 3,469,900 | $43,964,000 | thousands by filing date | |
| DIMENSION THERAPEUTICS INC | 25433V105 | COM | 5,397,698 | $42,264,000 | thousands by filing date | |
| COMMUNITY HEALTH SYSTEMS INC | 203668108 | COMMON STOCK | 2,171,400 | $40,193,000 | thousands by filing date | |
| BLUEBIRD BIO INC | 09609G100 | COM | 945,500 | $40,184,000 | thousands by filing date | |
| ACADIA PHARMACEUTICALS INC | 004225108 | COM | 1,401,600 | $39,189,000 | thousands by filing date | |
| DYNAVAX TECHNOLOGIES CORP | 268158201 | COM NEW | 1,974,700 | $37,993,000 | thousands by filing date | |
| Viewra, Inc | 92672L107 | COM | 7,989,916 | $34,357,000 | thousands by filing date | |
| ARRAY BIOPHARMA INC COM | 04269X105 | Stock | 10,689,000 | $31,533,000 | thousands by filing date | |
| ISHARES TR | 464287556 | ISHARES BIOTECH | 111,700 | $29,132,000 | thousands by filing date | |
| OTONOMY INC | 68906L105 | COM | 1,850,094 | $27,603,000 | thousands by filing date | |
| XENOPORT INC | 98411C100 | COM | 6,000,400 | $27,062,000 | thousands by filing date | |
| ALLERGAN PLC | G0177J108 | SHS | 100,000 | $26,803,000 | thousands by filing date | call |
| MEDIVATION INC | 58501N101 | COM | 501,000 | $23,036,000 | thousands by filing date | |
| Stryker Corporation | 863667101 | COM | 212,000 | $22,745,000 | thousands by filing date | |
| IMMUNOMEDICS INC | 452907AK4 | NOTE 4.750 2/1 | 30,000,000 | $20,384,000 | thousands by filing date | principal |
| INFINITY PHARMACEUTICALS INC | 45665G303 | COM | 3,723,528 | $19,623,000 | thousands by filing date | |
| PORTOLA PHARMACEUTICALS INC COM | 737010108 | Stock | 838,100 | $17,097,000 | thousands by filing date | |
| SINOVAC BIOTECH LTD | P8696W104 | SHS | 2,667,500 | $17,045,000 | thousands by filing date | |
| NEWLINK GENETICS CORP | 651511107 | COM | 817,006 | $14,870,000 | thousands by filing date | |
| XENCOR INC | 98401F105 | COMMON STOCK | 1,107,022 | $14,856,000 | thousands by filing date | |
| AFFIMED N V | N01045108 | COM | 3,931,800 | $14,705,000 | thousands by filing date | |
| STANDARD BIOTOOLS INC | 34385P108 | COM | 1,746,100 | $14,091,000 | thousands by filing date | |
| PIERIS PHARMACEUTICALS INC | 720795103 | COM | 7,259,620 | $13,793,000 | thousands by filing date | |
| GW PHARMACEUTICALS PLC | 36197T103 | ADS | 190,600 | $13,752,000 | thousands by filing date | |
| CARDINAL HEALTH INC | 14149Y108 | COM | 166,000 | $13,604,000 | thousands by filing date | |
| FORWARD PHARMA A/S | 34986J105 | SPONSORED ADR | 798,000 | $13,566,000 | thousands by filing date | |
| CYNAPSUS THERAPEUTICS INC | 23257Y859 | COM PAR NO PAR | 1,140,325 | $13,221,000 | thousands by filing date | |
| BAXALTA INC | 07177M103 | COM | 326,000 | $13,170,000 | thousands by filing date | |
| EXACT SCIENCES CORP COM | 30063P105 | Stock | 1,890,400 | $12,741,000 | thousands by filing date | |
| CLOVIS ONCOLOGY INC | 189464100 | COM | 660,900 | $12,689,000 | thousands by filing date | |
| EHEALTH INC | 28238P109 | COM | 1,300,000 | $12,207,000 | thousands by filing date | |
| NATERA INC COM | 632307104 | Stock | 1,276,190 | $12,149,000 | thousands by filing date | |
| MCKESSON CORP COM | 58155Q103 | Stock | 77,200 | $12,140,000 | thousands by filing date | |
| NABRIVA THERAPEUTICS AG | 62957M104 | SPONSORED ADR | 1,315,000 | $11,782,000 | thousands by filing date | |
| JAZZ PHARMACEUTICALS PLC SHS USD | G50871105 | Stock | 90,000 | $11,750,000 | thousands by filing date | |
| ENSIGN GROUP INC | 29358P101 | COM | 514,200 | $11,641,000 | thousands by filing date | |
| PROQR THERAPEUTICS NV | N71542109 | SHS EURO | 2,305,446 | $11,251,000 | thousands by filing date | |
| Merck & Co.,Inc. | 58933Y105 | COM | 210,400 | $11,132,000 | thousands by filing date | |
| HORIZON PHARMA INVT LTD | 44052TAB7 | NOTE 2.500% 3/1 | 13,000,000 | $11,128,000 | thousands by filing date | principal |
| ZIMMER BIOMET HOLDINGS INC COM | 98956P102 | Stock | 103,000 | $10,983,000 | thousands by filing date | |
| Sierra Oncology, Inc. | 74346L101 | common | 1,623,149 | $10,940,000 | thousands by filing date | |
| Rocket Pharmaceuticals Inc | 45780V102 | SHS | 1,391,000 | $10,293,000 | thousands by filing date | |
| EDWARDS LIFESCIENCES CORP COM | 28176E108 | Stock | 115,000 | $10,144,000 | thousands by filing date | |
| SYNDAX PHARMACEUTICALS INC | 87164F105 | COM | 757,365 | $10,088,000 | thousands by filing date | |
| Abbott Laboratories | 002824100 | COM | 237,000 | $9,914,000 | thousands by filing date | |
| CELLECTIS ADS | 15117K103 | COM | 350,000 | $9,625,000 | thousands by filing date | |
| LAKEFRONT BIOTHERAPEUTICS NV | 36315X101 | SPON ADR | 230,000 | $9,619,000 | thousands by filing date | |
| IMMUNOMEDICS INC | 452907108 | COM | 3,802,000 | $9,505,000 | thousands by filing date | |
| SIENTRA INC | 82621J105 | COM | 1,357,500 | $9,285,000 | thousands by filing date | |
| AETNA INC NEW | 00817Y108 | COM | 76,000 | $8,539,000 | thousands by filing date | |
| INTRA-CELLULAR THERAPIES INC | 46116X101 | COMMON STOCK | 294,000 | $8,173,000 | thousands by filing date | |
| ULTRAGENYX PHARMACEUTICAL IN | 90400D108 | COM | 128,300 | $8,123,000 | thousands by filing date | |
| ENANTA PHARMACEUTICALS INC | 29251M106 | COM | 249,400 | $7,325,000 | thousands by filing date | |
| BIOTIE THERAPIES OYJ | 09074D103 | SPONSORED ADR | 268,672 | $7,090,000 | thousands by filing date | |
| ASSEMBLY BIOSCIENCES INC | 045396108 | COM | 1,397,100 | $7,013,000 | thousands by filing date | |
| REDHILL BIOPHARMA LTD | 757468103 | ADR | 564,900 | $6,920,000 | thousands by filing date | |
| INCYTE CORP | 45337CAN2 | NOTE 1.250%11/1 | 4,250,000 | $6,727,000 | thousands by filing date | principal |
| INCYTE CORP | 45337CAM4 | NOTE 0.375%11/1 | 4,250,000 | $6,574,000 | thousands by filing date | principal |
| SYNERGY PHARMACEUTICALS DEL | 871639308 | COM NEW | 2,276,648 | $6,284,000 | thousands by filing date | |
| MACROGENICS INC | 556099109 | COM | 317,000 | $5,944,000 | thousands by filing date | |
| ADVAXIS INC | 007624208 | COM NEW | 636,600 | $5,748,000 | thousands by filing date | |
| QIAGEN NV | N72482107 | COMMON STOCK-FO | 256,800 | $5,737,000 | thousands by filing date | |
| STANDARD BIOTOOLS INC | 34385PAA6 | NOTE 2.750% 2/0 | 10,000,000 | $5,553,000 | thousands by filing date | principal |
| MARINUS PHARMACEUTICALS INC | 56854Q101 | COM | 965,000 | $5,192,000 | thousands by filing date | |
| Lion Biotechnologies | 53619R102 | COM | 1,022,100 | $5,192,000 | thousands by filing date | |
| VALEANT PHARMACEUTICALS INTL | 91911K102 | COM | 194,900 | $5,126,000 | thousands by filing date | |
| INVITAE CORP | 46185L103 | COM | 456,666 | $4,672,000 | thousands by filing date | |
| CONNECTURE INC COM | 20786J106 | Stock | 1,740,000 | $4,454,000 | thousands by filing date | |
| SERES THERAPEUTICS INC | 81750R102 | COM | 166,645 | $4,426,000 | thousands by filing date | |
| MIRATI THERAPEUTICS INC | 60468T105 | COM | 197,859 | $4,234,000 | thousands by filing date | |
| ASCENDIS PHARMA A/S DKK 1.0 AD | 04351P101 | SPONSORED ADR | 222,223 | $4,122,000 | thousands by filing date | |
| ADAPTIMMUNE THERAPEUTICS PLC | 00653A107 | SPONDS ADR | 438,784 | $3,567,000 | thousands by filing date | |
| CERUS CORP | 157085101 | COM | 578,300 | $3,429,000 | thousands by filing date | |
| MYLAN NV | N59465109 | SHS EURO | 69,800 | $3,235,000 | thousands by filing date | |
| ANACOR PHARMACEUTICALS INC | 032420101 | COM | 53,300 | $2,849,000 | thousands by filing date | |
| ALIMERA SCIENCES INC | 016259103 | COM | 1,500,000 | $2,625,000 | thousands by filing date | |
| ROKA BIOSCIENCE INC | 775431109 | COM | 3,220,429 | $2,222,000 | thousands by filing date | |
| UNIQURE NV | N90064101 | SHS | 184,800 | $2,195,000 | thousands by filing date | |
| OREXIGEN THERAPEUTICS INC | 686164AB0 | NOTE 2.750%12/0 | 5,210,000 | $2,149,000 | thousands by filing date | principal |
| PORTOLA PHARMACEUTICALS INC COM | 737010108 | Stock | 100,000 | $2,040,000 | thousands by filing date | put |
| MEDIGUS LTD | 58471G102 | SPONSORED ADR | 600,000 | $1,608,000 | thousands by filing date | |
| ACHILLION PHARMACEUTICALS IN | 00448Q201 | COM | 200,000 | $1,544,000 | thousands by filing date | call |
| XTNT | 98420P100 | Common | 475,439 | $1,288,000 | thousands by filing date | |
| FATE THERAPEUTICS INC | 31189P102 | COM | 692,900 | $1,247,000 | thousands by filing date | |
| PERNIX THERAPEUTICS HOLDINGS | 71426V108 | COM | 1,073,000 | $1,127,000 | thousands by filing date | |
| COGENTIX MED INC COM | 19243A104 | Stock | 990,745 | $1,090,000 | thousands by filing date | |
| BIOLINERX LTD-SPONS ADR | 09071M106 | SPON | 1,038,600 | $1,059,000 | thousands by filing date | |
| QLT INC | 746927102 | COMMON STOCK | 500,000 | $995,000 | thousands by filing date | |
| BIOMARIN PHARMACEUTICAL INC | 09061GAF8 | NOTE 1.500%10/1 | 500,000 | $594,000 | thousands by filing date | principal |
| BIOMARIN PHARMACEUTICAL INC | 09061GAE1 | NOTE 0.750%10/1 | 500,000 | $579,000 | thousands by filing date | principal |
| AMARIN CORP PLC | 023111206 | SPONS ADR NEW | 350,000 | $536,000 | thousands by filing date |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001172661-16-003439 | this filing | 2016-05-16 | acceptance time not in the bulk data set |