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13F-HR filed by ORBIMED ADVISORS LLC

ORBIMED ADVISORS LLC filed this 13F-HR for the quarter ended 2014-12-31, filed 2015-02-13, with 131 holding rows worth $10,464,861,000.

Accession
0001172661-15-000419
Filed
2015-02-13
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q4 2014

A holdings report, 131 entries on the cover page, a total value of $10,464,861,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $10,464,861,000 with VALUE read as thousands by filing date, 13F file number 028-06774. The quarter's positions are built on this report. The resolved quarter.

Other managers

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
BIOGEN INC COM09062X103Stock1,494,700$507,376,000thousands by filing date
Bristol-Myers Squibb Company110122108COM7,688,700$453,864,000thousands by filing date
Amgen Inc.031162100COM2,708,000$431,357,000thousands by filing date
CELGENE CORP151020104COM3,657,600$409,139,000thousands by filing date
Gilead Sciences,Inc.375558103COM4,249,500$400,558,000thousands by filing date
ACTAVIS PLCG0083B108SHS1,488,200$383,078,000thousands by filing date
AbbVie,Inc.00287Y109COM5,331,100$348,867,000thousands by filing date
HCA Healthcare Inc40412C101COM4,308,000$316,164,000thousands by filing date
RELYPSA INC759531106Common Stock8,857,551$272,813,000thousands by filing date
ILLUMINA INC452327109COM1,476,600$272,551,000thousands by filing date
SHIRE PLC82481R106COMMON STOCK-FO1,170,000$248,672,000thousands by filing date
Intuitive Surgical,Inc.46120E602COM440,000$232,734,000thousands by filing date
INTERCEPT PHARMACEUTICALS IN45845P108COM1,485,000$231,660,000thousands by filing date
INCYTE CORP COM45337C102Stock3,149,300$230,245,000thousands by filing date
MEDIVATION INC58501N101COM2,268,900$226,005,000thousands by filing date
IMPAX LABORATORIES INC45256B101COM6,678,000$211,559,000thousands by filing date
PERRIGO CO PLC SHSG97822103Stock1,247,800$208,582,000thousands by filing date
Vertex Pharmaceuticals Incorporated92532F100COM1,731,200$205,667,000thousands by filing date
Thermo Fisher Scientific Inc.883556102COM1,595,700$199,925,000thousands by filing date
Lowes Companies Inc42222G108LOW3,711,400$198,671,000thousands by filing date
THE COOPER COMPANIES216648402COM NEW1,220,600$197,847,000thousands by filing date
EXPRESS SCRIPTS HLDG CO30219G108COM2,307,000$195,334,000thousands by filing date
MOLINA HEALTHCARE INC60855R100COM3,581,900$191,739,000thousands by filing date
IRONWOOD PHARMACEUTICALS INC46333X108COMMON STOCK12,012,100$184,025,000thousands by filing date
AGILENT TECHNOLOGIES INC COM00846U101Stock4,051,000$165,848,000thousands by filing date
Merck & Co.,Inc.58933Y105COM2,915,300$165,560,000thousands by filing date
REGENERON PHARMACEUTICALS COM75886F107Stock390,200$160,080,000thousands by filing date
ALLERGAN INC018490102COM741,300$157,593,000thousands by filing date
MCKESSON CORP COM58155Q103Stock742,000$154,024,000thousands by filing date
ZIMMER BIOMET HOLDINGS INC COM98956P102Stock1,282,700$145,484,000thousands by filing date
NEUROCRINE BIOSCIENCES INC64125C109COM5,968,600$133,339,000thousands by filing date
TORNIER NVN87237108COMMON STOCK-FO4,805,000$122,528,000thousands by filing date
NPS PHARMACEUTICALS INC62936P103COM2,954,900$105,697,000thousands by filing date
Stryker Corporation863667101COM1,031,600$97,311,000thousands by filing date
INSULET CORP COM45784P101Stock1,997,000$91,982,000thousands by filing date
Pfizer Inc.717081103COM2,759,000$85,943,000thousands by filing date
INFINITY PHARMACEUTICALS INC45665G303COM4,736,900$80,006,000thousands by filing date
OTONOMY INC68906L105COM2,256,398$75,206,000thousands by filing date
MAGELLAN HEALTH SERVICES INC559079207COM NEW1,208,000$72,516,000thousands by filing date
STANDARD BIOTOOLS INC34385P108COM2,136,200$72,054,000thousands by filing date
WRIGHT MED GROUP INC98235T107COM2,527,000$67,900,000thousands by filing date
AFFYMETRIX INC00826T108COM6,568,000$64,826,000thousands by filing date
ALEXION PHARMACEUTICALS INC015351109COM332,000$61,430,000thousands by filing date
Mallinckrodt PlcG5785G107SHS567,001$56,150,000thousands by filing date
SIENTRA INC82621J105COM3,185,308$53,481,000thousands by filing date
ALLERGAN INC018490102COM250,000$53,148,000thousands by filing datecall
INSYS THERAPEUTICS INC45824V209COMMON STOCK1,243,200$52,413,000thousands by filing date
Johnson & Johnson478160104COM495,000$51,762,000thousands by filing date
NUVASIVE INC670704105COM1,072,000$50,556,000thousands by filing date
TESARO INC881569107COM1,330,000$49,463,000thousands by filing date
EXACT SCIENCES CORP COM30063P105Stock1,778,000$48,788,000thousands by filing date
XENOPORT INC98411C100COM5,546,100$48,639,000thousands by filing date
PUMA BIOTECHNOLOGY INC74587V107COMMON STOCK250,900$47,488,000thousands by filing date
CERUS CORP157085101COM7,035,000$43,898,000thousands by filing date
SPY78462F103SHS200,000$41,108,000thousands by filing dateput
CLOVIS ONCOLOGY INC189464100COM714,100$39,990,000thousands by filing date
PROQR THERAPEUTICS NVN71542109SHS EURO1,829,400$39,643,000thousands by filing date
OPHTHOTECH CORP683745103COM861,800$38,669,000thousands by filing date
CELLDEX THERAPEUTICS INC NEW15117B103COM2,062,200$37,635,000thousands by filing date
AFFIMED N VN01045108COM5,814,630$36,051,000thousands by filing date
MEDTRONIC INC585055106COM493,800$35,652,000thousands by filing date
INCYTE CORP45337CAJ1NOTE 4.750%10/04,242,000$35,309,000thousands by filing dateprincipal
ARRAY BIOPHARMA INC COM04269X105Stock7,247,700$34,282,000thousands by filing date
CARDINAL HEALTH INC14149Y108COM325,000$26,237,000thousands by filing date
COVIDIEN PLCG2554F113SHS250,000$25,570,000thousands by filing datecall
LOXO ONCOLOGY INC548862101COM2,175,857$25,566,000thousands by filing date
KYTHERA BIOPHARMACEUTICALS I501570105COM722,900$25,070,000thousands by filing date
PORTOLA PHARMACEUTICALS INC COM737010108Stock850,700$24,092,000thousands by filing date
UnitedHealth Group Inc91324P102COM235,000$23,756,000thousands by filing date
VALEANT PHARMACEUTICALS INTL91911K102COM162,000$23,184,000thousands by filing date
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS881624209ADR400,000$23,004,000thousands by filing date
MIRATI THERAPEUTICS INC60468T105COM1,167,000$21,613,000thousands by filing date
COVIDIEN PLCG2554F113SHS211,200$21,602,000thousands by filing date
ORASURE TECHNOLOGIES INC68554V108COM1,978,500$20,062,000thousands by filing date
FORWARD PHARMA A/S34986J105SPONSORED ADR960,600$20,009,000thousands by filing date
AMAG PHARMACEUTICALS INC00163U106COM469,000$19,989,000thousands by filing date
STANDARD BIOTOOLS INC34385PAA6NOTE 2.750% 2/021,935,000$19,851,000thousands by filing dateprincipal
RECEPTOS, INC.756207106COMMON STOCK156,100$19,124,000thousands by filing date
JAZZ PHARMACEUTICALS PLC SHS USDG50871105Stock115,000$18,829,000thousands by filing date
Elevance Health, Inc.036752103COM138,800$17,443,000thousands by filing date
XENCOR INC98401F105COMMON STOCK1,046,000$16,778,000thousands by filing date
MERGE HEALTHCARE INC589499102COM4,628,500$16,477,000thousands by filing date
PACIRA BIOSCIENCES INC COM695127100Stock176,000$15,604,000thousands by filing date
SAGE THERAPEUTICS INC78667J108COM412,335$15,091,000thousands by filing date
VOLCANO CORP928645AB6CORPORATE OBLIG15,000,000$14,865,000thousands by filing dateprincipal
Bristol-Myers Squibb Company110122108COM250,000$14,758,000thousands by filing datecall
SINOVAC BIOTECH LTDP8696W104SHS2,821,500$14,756,000thousands by filing date
ROKA BIOSCIENCE INC775431109COM3,220,429$14,202,000thousands by filing date
HORIZON PHARMA PLCG4617B105SHS1,075,000$13,857,000thousands by filing date
ST JUDE MED INC790849103COM173,000$11,250,000thousands by filing date
SHIRE PLC82481R106COMMON STOCK-FO50,000$10,627,000thousands by filing datecall
MEI PHARMA INC55279B202COM NEW2,424,500$10,353,000thousands by filing date
PERNIX THERAPEUTICS HOLDINGS71426V108COM1,073,000$10,075,000thousands by filing date
AGENUS INC00847G705COM NEW2,441,500$9,693,000thousands by filing date
MIMEDX GROUP INC602496101COM836,800$9,648,000thousands by filing date
Abbott Laboratories002824100COM211,000$9,499,000thousands by filing date
SALIX PHARMACEUTICALS INC795435106COM82,000$9,425,000thousands by filing date
AEGERION PHARMACEUTICALS INC00767E102COM400,000$8,376,000thousands by filing datecall
AETNA INC NEW00817Y108COM94,000$8,350,000thousands by filing date
ALIMERA SCIENCES INC016259103COM1,500,000$8,310,000thousands by filing date
REDHILL BIOPHARMA LTD757468103ADR605,800$8,075,000thousands by filing date
OREXIGEN THERAPEUTICS INC686164AB0NOTE 2.750%12/07,500,000$7,538,000thousands by filing dateprincipal
SYNAGEVA BIOPHARMA CORP87159A103COM77,800$7,219,000thousands by filing date
XOMA CORP DEL98419J107COM2,000,000$7,180,000thousands by filing date
ARQULE INC04269E107COM5,702,000$6,956,000thousands by filing date
INCYTE CORP45337CAN2NOTE 1.250%11/14,250,000$6,558,000thousands by filing dateprincipal
INCYTE CORP45337CAM4NOTE 0.375%11/14,250,000$6,425,000thousands by filing dateprincipal
REGULUS THERAPEUTICS INC75915K101COM400,000$6,416,000thousands by filing date
DAVITA INC COM23918K108Stock76,000$5,756,000thousands by filing date
AUSPEX PHARMACE05211J102Common Stock93,600$4,912,000thousands by filing date
SUPERNUS PHARMACEUTICALS868459108COM580,000$4,814,000thousands by filing date
IMPAX LABORATORIES INC45256B101COM150,000$4,752,000thousands by filing datecall
Boston Scientific Corporation101137107COM320,000$4,240,000thousands by filing date
NEWLINK GENETICS CORP651511107COM100,000$3,975,000thousands by filing datecall
FATE THERAPEUTICS INC31189P102COM692,900$3,485,000thousands by filing date
SEATTLE GENETICS INC812578102COM100,000$3,213,000thousands by filing dateput
CURIS INC231269101COM1,950,100$2,925,000thousands by filing date
UROPLASTY INC917277204COM NEW1,363,500$2,809,000thousands by filing date
DERMA SCIENCES INC249827502COM PAR $.01300,000$2,793,000thousands by filing date
CONNECTURE INC COM20786J106Stock302,300$2,724,000thousands by filing date
INSPIREMD INC45779A309COM3,150,000$2,449,000thousands by filing date
ACHILLION PHARMACEUTICALS IN00448Q201COM158,000$1,936,000thousands by filing date
BIOLINERX LTD-SPONS ADR09071M106SPON1,135,000$1,839,000thousands by filing date
SANGAMO THERAPEUTICS INC800677106COM100,000$1,521,000thousands by filing datecall
BACTERIN INTL HLDGS INC05644R200COM NEW475,439$1,441,000thousands by filing date
CEMPRA INC15130J109COM50,000$1,176,000thousands by filing date
ENDOLOGIX INC29266SAA4NOTE 2.250%12/11,000,000$980,000thousands by filing dateprincipal
BIOMARIN PHARMACEUTICAL INC09061GAF8NOTE 1.500%10/1500,000$611,000thousands by filing dateprincipal
BIOMARIN PHARMACEUTICAL INC09061GAE1NOTE 0.750%10/1500,000$593,000thousands by filing dateprincipal
AMARIN CORP PLC023111206SPONS ADR NEW400,000$392,000thousands by filing date
BIODEL INC09064M204COM209,700$279,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001172661-15-000419this filing2015-02-13acceptance time not in the bulk data set