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13F-HR filed by MANUFACTURERS LIFE INSURANCE COMPANY, THE

MANUFACTURERS LIFE INSURANCE COMPANY, THE filed this 13F-HR for the quarter ended 2021-09-30, filed 2021-11-12, with 3,139 holding rows worth $122,246,378,000.

Accession
0001145443-21-000383
Filed
2021-11-12
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q3 2021

A holdings report, 4,943 entries on the cover page, a total value of $122,246,378,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $122,246,377,000 with VALUE read as thousands by filing date, 13F file number 028-04428. The quarter's positions are built on this report. The resolved quarter.

Other managers

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
Instil Bio, Inc.45783C101Common Stock10,785$193,000thousands by filing date
RIVERVIEW BANCORP INC769397100COM26,448$192,000thousands by filing date
BEYONDSPRING INCG10830100SHS12,093$191,000thousands by filing date
SQZ BIOTECHNOLOGIES CO78472W104COM13,240$191,000thousands by filing date
ALIGOS THERAPEUTICS INC COM NEW01626L105Stock12,276$190,000thousands by filing date
BAOZUN INC ADR06684L103SPONSORED ADR10,800$189,000thousands by filing date
LINEAGE CELL THERAPEUTICS IN53566P109COMMON STOCK74,991$189,000thousands by filing date
LEXICON PHARMACEUTICALS INC528872302COMMON STOCK39,070$188,000thousands by filing date
ATHIRA PHARMA INC04746L104COM20,014$188,000thousands by filing date
THERAPEUTICSMD INC88338N107COM253,880$188,000thousands by filing date
SIENTRA INC82621J105COM32,652$187,000thousands by filing date
MEI PHARMA INC55279B202COM NEW67,338$186,000thousands by filing date
COMMERCIAL VEH GROUP INC202608105COM19,459$184,000thousands by filing date
ESPERION THERAPEUTICS INC NEW COM29664W105Stock15,098$182,000thousands by filing date
CLEARPOINT NEURO INC18507C103COM10,254$182,000thousands by filing date
COGENT BIOSCIENCES INC19240Q201COM21,678$182,000thousands by filing date
Ampio Pharmaceuticals03209T109COM109,516$182,000thousands by filing date
Applied Therapeutics Inc03828A101Common Stock10,923$181,000thousands by filing date
Rithm Property Trust Inc38983D300REIT13,422$181,000thousands by filing date
LUNA INNOVATIONS INC550351100COM19,045$181,000thousands by filing date
RPC INC749660106COMMON STOCK37,013$180,000thousands by filing date
9 METERS BIOPHARMA INC654405109COM137,952$179,000thousands by filing date
WEBER INC94770D102COM10,155$179,000thousands by filing date
F45 TRAINING HLDGS INC30322L101COM11,954$179,000thousands by filing date
CAESARSTONE LTDM20598104ORD SHS14,233$177,000thousands by filing date
INFRA AND ENERGY ALTRNTIVE I45686J104COM15,367$176,000thousands by filing date
VISTRA CORP COM92840M102Stock10,218$175,000thousands by filing date
EASTMAN KODAK CO277461406COM NEW25,682$175,000thousands by filing date
PARK AEROSPACE CORP70014A104COM12,714$174,000thousands by filing date
SAFE BULKERS INCY7388L103COMMON STOCK33,703$174,000thousands by filing date
TCR2 THERAPEUTICS INC87808K106COM20,402$174,000thousands by filing date
FLEXION THERAPEUTICS INC33938J106COM28,517$174,000thousands by filing date
QUANTUM CORP747906501COM33,163$172,000thousands by filing date
VIRACTA THERAPEUTICS INC92765F108COM21,378$171,000thousands by filing date
INFINITY PHARMACEUTICALS INC45665G303COM49,778$170,000thousands by filing date
ARCIMOTO INC039587100COM14,878$170,000thousands by filing date
AKOUOS INC00973J101COM14,578$169,000thousands by filing date
LIFECOREBIOMEDICALINC514766104STOK18,265$168,000thousands by filing date
BENEFITFOCUS INC08180D106COM15,109$168,000thousands by filing date
CONTAINER STORE GROUP INC210751103COMMON STOCK17,505$167,000thousands by filing date
YELLOW CORP985510106COM29,562$167,000thousands by filing date
ATHERSYS INC04744L106COM125,310$167,000thousands by filing date
BRAEMAR HOTELS RESORTS INC10482B101REIT34,193$166,000thousands by filing date
CARDIFF ONCOLOGY INC14147L108COM24,853$166,000thousands by filing date
NIAGEN BIOSCIENCE INC171077407COM NEW26,234$164,000thousands by filing date
SURFACE ONCOLOGY INC86877M209COM21,704$164,000thousands by filing date
AVEANNA HEALTHCARE HLDGS INC05356F105COM20,334$163,000thousands by filing date
ATERIAN INC02156U101COM15,060$163,000thousands by filing date
HARVARD BIOSCIENCE INC416906105COM23,041$161,000thousands by filing date
EROS INTL PLCG3788M114SHS NEW175,294$161,000thousands by filing date
STEREOTAXIS INC85916J409COMMON STOCK29,535$159,000thousands by filing date
CENOVUS ENERGY INC15135U117*W EXP 01/01/20221,260$159,000thousands by filing date
KRISPY KREME INC50101L106COMMON STOCK11,302$158,000thousands by filing date
ASHFORD HOSPITALITY TR INC044103869COM SHS10,747$158,000thousands by filing date
NEXIMMUNE INC65344D109COM10,464$158,000thousands by filing date
CARLOTZ INC142552108COMMON STOCK41,122$157,000thousands by filing date
NAUTILUS INC63910B102COMMON STOCK16,865$157,000thousands by filing date
IBIO INC451033203COM NEW146,481$155,000thousands by filing date
DONEGAL GROUP INC CL A257701201COMMON STOCK10,639$154,000thousands by filing date
ATHENEX INC04685N103COM51,222$154,000thousands by filing date
CURIOSITYSTREAM INC23130Q107COMMON STOCK14,512$153,000thousands by filing date
SYROS PHARMACEUTICALS INC87184Q107COM34,245$153,000thousands by filing date
BROOKLYN IMMUNOTHERAPEUTICS114082100COM16,451$153,000thousands by filing date
Up Fintech Holding Ltd91531W106COM14,300$151,000thousands by filing date
MESA AIR GROUP INC590479135COM NEW19,752$151,000thousands by filing date
CHEGG INC163092AF6NOTE 9/01,520,000$150,000thousands by filing dateprincipal
HF FOODS GROUP INC40417F109COM24,792$150,000thousands by filing date
PLAINS ALL AMERN PIPELINE L726503105UNIT LTD PARTN14,426$147,000thousands by filing date
JOUNCE THERAPEUTICS INC481116101COM19,784$147,000thousands by filing date
TECTONIC THERAPEUTIC INC COM05455M100Stock26,403$147,000thousands by filing date
Matrix Service Company576853105COM13,741$144,000thousands by filing date
EVOLUS INC30052C107COM18,705$143,000thousands by filing date
TONIX PHARMACEUTICALS HOLDIN890260706COM236,958$142,000thousands by filing date
SENSEI BIOTHERAPEUTICS INC81728A108COM13,478$142,000thousands by filing date
HUMANIGEN INC444863203COM NEW23,676$140,000thousands by filing date
BOLT BIOTHERAPEUTICS INC097702104COM11,017$139,000thousands by filing date
ACUTUS MED INC005111109COM15,558$138,000thousands by filing date
ZEVRA THERAPEUTICS INC COM NEW488445206Stock14,642$137,000thousands by filing date
ARS PHARMACEUTICALS INC82835W108COM13,766$137,000thousands by filing date
DAKTRONICS INC234264109COM24,786$135,000thousands by filing date
CHINDATA GROUP HLDGS LTD16955F107ADS16,000$135,000thousands by filing date
LIBERTY TRIPADVISOR HLDGS IN531465102COM SER A43,512$134,000thousands by filing date
ASPIRA WOMENS HEALTH INC04537Y109COM41,371$134,000thousands by filing date
CONCRETE PUMPING HOLDINGS IN206704108COMMON STOCK15,510$132,000thousands by filing date
ANGI INC CLASS A00183L102CL A10,603$131,000thousands by filing date
GTY TECHNOLOGY HOLDINGS INC362409104COM17,201$129,000thousands by filing date
KRONOS WORLDWIDE INC COM50105F105Stock10,236$127,000thousands by filing date
ADT INC DEL COM00090Q103Stock15,587$126,000thousands by filing date
HUYA INC ADS EACH REP 1 ORD SHS CL A44852D108COM15,000$125,000thousands by filing date
KEZAR LIFE SCIENCES INC49372L100COM14,363$124,000thousands by filing date
HONEST CO INC438333106COM11,430$119,000thousands by filing date
EVGO INC30052F100CL A COM14,172$116,000thousands by filing date
ANGION BIOMEDICA CORP03476J107COM11,708$114,000thousands by filing date
FUTUREFUEL CORP36116M106COMMON STOCK15,854$113,000thousands by filing date
EYEPOINT INC COM NEW30233G209Stock10,656$111,000thousands by filing date
PARATEK PHARMACEUTICALS INC699374302Equity22,520$109,000thousands by filing date
DOMA HOLDINGS INC25703A104COM14,299$106,000thousands by filing date
TIPTREE INC88822Q103COM10,204$102,000thousands by filing date
MOLECULAR TEMPLATES INC608550109COM15,235$102,000thousands by filing date
EMCORE CORP290846203COM13,043$98,000thousands by filing date
COMSCORE INC20564W105COM24,399$95,000thousands by filing date
RADIANT LOGISTICS INC75025X100COM14,244$91,000thousands by filing date
CECO ENVIRONMENTAL CORP125141101COM12,890$91,000thousands by filing date
DURECT CORP266605104COM69,957$90,000thousands by filing date
ONECONNECT FINL TECHNOLOGY C68248T105ADR21,800$89,000thousands by filing date
TREVENA INC89532E109COM72,167$89,000thousands by filing date
VIRNETX HLDG CORP92823T108COM22,178$87,000thousands by filing date
NEOLEUKIN THERAPEUTICS INC64049K104COM11,580$84,000thousands by filing date
QUOTIENT LTDG73268107SHS35,865$84,000thousands by filing date
CYMABAY THERAPEUTICS INC23257D103COM22,272$81,000thousands by filing date
VIEMED HEALTHCARE INC92663R105COM11,051$78,000thousands by filing date
PAYSAFE LIMITEDG6964L107ORD10,000$78,000thousands by filing date
SMITH MICRO SOFTWARE INC832154207COMMON15,864$77,000thousands by filing date
MUSTANG BIO INC62818Q104COM28,199$76,000thousands by filing date
EVELO BIOSCIENCES INC299734103COM10,483$74,000thousands by filing date
ENLINK MIDSTREAM LLC29336T100COM UNIT REP LTD10,548$72,000thousands by filing date
CORENERGY INFRASTRUCTURE TR21870U502TRUS16,258$72,000thousands by filing date
EARGO INC270087109COM10,751$72,000thousands by filing date
Accelerate Diagnostics00430H102COM12,096$71,000thousands by filing date
ONCOCYTE CORP68235C107COM19,842$71,000thousands by filing date
NPK INTERNATIONAL INC651718504COMMON STOCK21,203$70,000thousands by filing date
Gaotu Techedu Inc36257Y109COM21,000$64,000thousands by filing date
CONTEXTLOGIC INC21077C107COMMON STOCK11,179$61,000thousands by filing date
FORTRESS BIOTECH INC34960Q109COM17,489$56,000thousands by filing date
FORTE BIOSCIENCES INC34962G109COM13,900$41,000thousands by filing date
SEELOS THERAPEUTICS INC81577F109COM13,615$33,000thousands by filing date
MATINAS BIOPHARMA HLDGS INC576810105COM18,954$25,000thousands by filing date
CITIUS PHARMACEUTICALS INC17322U207COM11,188$23,000thousands by filing date
NEOGENOMICS INC64049MAB6NOTE 0.250% 1/1214,000$22,000thousands by filing dateprincipal
NEWAGE INC650194103COMMON STOCK15,367$21,000thousands by filing date
ARDELYX INC039697107COM15,173$20,000thousands by filing date
BIORA THERAPEUTICS INC74319F107COM13,396$20,000thousands by filing date
SERVICESOURCE INTL LLC81763U100COM14,242$19,000thousands by filing date
IDERA PHARMACEUTICALS INC45168K405COM PAR13,933$14,000thousands by filing date
ADVAXIS INC007624307COM21,355$11,000thousands by filing date
THERIVA BIOLOGICS INC COM NEW87164U201Stock23,577$11,000thousands by filing date
REGULUS THERAPEUTICS INC75915K200COM NEW10,610$7,000thousands by filing date
BAUDAX BIO INC07160F107COM12,510$7,000thousands by filing date
ZOMEDICA CORP COM98980M109Stock11,482$6,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001145443-21-000383this filing2021-11-12acceptance time not in the bulk data set