13F-HR filed by Avoro Capital Advisors LLC
Avoro Capital Advisors LLC filed this 13F-HR for the quarter ended 2023-12-31, filed 2024-02-14, with 42 holding rows worth $7,239,756,496.
- Accession
- 0001104659-24-023272
- Filer
- CIK 1633313
- Filed
- 2024-02-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2023
A holdings report, 42 entries on the cover page, a total value of $7,239,756,496 stated on the cover page (in dollars after the unit check, H1), rows summing to $7,239,756,496 with VALUE read as dollars as filed, 13F file number 028-16573. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| APELLIS PHARMACEUTICALS INC | 03753U106 | COM | 11,111,111 | $665,111,104 | dollars as filed | |
| UNITED THERAPEUTICS CORP DEL COM | 91307C102 | Stock | 2,858,888 | $628,640,882 | dollars as filed | |
| ASCENDIS PHARMA A/S DKK 1.0 AD | 04351P101 | SPONSORED ADR | 3,755,555 | $473,012,152 | dollars as filed | |
| ARGENX SE SPONSORED ADR | 04016X101 | ADR | 1,234,567 | $469,666,324 | dollars as filed | |
| MADRIGAL PHARMACEUTICALS INC COM | 558868105 | Stock | 1,888,888 | $437,050,905 | dollars as filed | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 4,344,444 | $418,934,735 | dollars as filed | |
| BIOMARIN PHARMACEUTICAL INC | 09061G101 | COM | 4,300,000 | $414,606,000 | dollars as filed | |
| SPDR SER TR | 78464A870 | S&P BIOTECH | 4,444,444 | $396,844,405 | dollars as filed | |
| AMICUS THERAPEUTICS INC | 03152W109 | COM | 27,400,000 | $388,806,000 | dollars as filed | |
| CEREVEL THERAPEUTICS HLDNG I | 15678U128 | COM | 7,555,555 | $320,355,532 | dollars as filed | |
| KRYSTAL BIOTECH INC COM | 501147102 | Stock | 2,565,555 | $318,282,753 | dollars as filed | |
| MIRATI THERAPEUTICS INC | 60468T105 | COM | 4,886,840 | $287,101,850 | dollars as filed | |
| CYMABAY THERAPEUTICS INC | 23257D103 | COM | 11,111,111 | $262,444,442 | dollars as filed | |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 5,666,666 | $261,006,636 | dollars as filed | |
| ALNYLAM PHARMACEUTICALS INC COM | 02043Q107 | Stock | 1,111,111 | $212,677,757 | dollars as filed | |
| INTRA-CELLULAR THERAPIES INC | 46116X101 | COMMON STOCK | 2,255,555 | $161,542,849 | dollars as filed | |
| MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD | 61559X104 | Stock | 2,580,000 | $155,806,200 | dollars as filed | |
| KYMERA THERAPEUTICS INC | 501575104 | COM | 3,775,000 | $96,111,500 | dollars as filed | |
| STRUCTURE THERAPEUTICS INC COMP | 86366E106 | EQUITY | 2,333,333 | $95,106,653 | dollars as filed | |
| SYNDAX PHARMACEUTICALS INC | 87164F105 | COM | 4,222,222 | $91,242,217 | dollars as filed | |
| BIOCRYST PHARMACEUTICALS INC COM | 09058V103 | Stock | 13,050,000 | $78,169,500 | dollars as filed | |
| IOVANCE BIOTHERAPEUTICS INC | 462260100 | COM | 6,700,000 | $54,471,000 | dollars as filed | |
| ROIVANT SCIENCES LTD | G76279101 | SHS | 4,651,162 | $52,232,549 | dollars as filed | |
| KURA ONCOLOGY INC COM | 50127T109 | Stock | 2,980,000 | $42,852,400 | dollars as filed | |
| SPYRE THERAPEUTICS INC | 00773J202 | COM NEW | 1,839,138 | $39,578,250 | dollars as filed | |
| KARUNA THERAPEUTICS INC | 48576A100 | COM | 125,000 | $39,563,750 | dollars as filed | |
| ROCKET PHARMACEUTICALS INC | 77313F106 | COM | 1,260,900 | $37,789,173 | dollars as filed | |
| ARROWHEAD PHARMACEUTICALS IN | 04280A100 | COM | 1,130,000 | $34,578,000 | dollars as filed | |
| MARINUS PHARMACEUTICALS INC | 56854Q200 | COM NEW | 3,150,000 | $34,240,500 | dollars as filed | |
| MANNKIND CORP COM NEW | 56400P706 | Stock | 9,000,000 | $32,760,000 | dollars as filed | |
| SOLENO THERAPEUTICS INC | 834203309 | COM | 785,000 | $31,596,250 | dollars as filed | |
| VERRICA PHARMACEUTICALS INC | 92511W108 | COM | 3,999,999 | $29,279,993 | dollars as filed | |
| IMMUNOGEN INC | 45253H101 | COMMON STOCK | 875,000 | $25,943,750 | dollars as filed | |
| MONTE ROSA THERAPEUTICS INC | 61225M102 | COM | 4,535,000 | $25,622,750 | dollars as filed | |
| MERUS N V | N5749R100 | COM | 888,888 | $24,444,420 | dollars as filed | |
| Tourmaline Bio Inc | 89157D105 | Common Stock | 868,407 | $22,734,895 | dollars as filed | |
| AVIDITY BIOSCIENCES INC COM | 05370A108 | Stock | 2,510,000 | $22,715,500 | dollars as filed | |
| ULTRAGENYX PHARMACEUTICAL IN | 90400D108 | COM | 350,000 | $16,737,000 | dollars as filed | |
| FENNEC PHARMACEUTICALS INC | 31447P100 | COMMON STOCK | 1,200,000 | $13,464,000 | dollars as filed | |
| NUVALENT INC COM | 670703107 | Stock | 178,921 | $13,166,796 | dollars as filed | |
| TAYSHA GENE THERAPIES INC | 877619106 | COMMON STOCK | 4,355,555 | $7,709,332 | dollars as filed | |
| WHITEHAWK THERAPEUTICS INC | 00032Q104 | CMN | 2,849,402 | $5,755,792 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001104659-24-023272 | this filing | 2024-02-14 | acceptance time not in the bulk data set |