13F-HR filed by Avoro Capital Advisors LLC
Avoro Capital Advisors LLC filed this 13F-HR for the quarter ended 2022-12-31, filed 2023-02-14, with 36 holding rows worth $6,691,518,385.
- Accession
- 0001104659-23-020884
- Filer
- CIK 1633313
- Filed
- 2023-02-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2022
A holdings report, 36 entries on the cover page, a total value of $6,691,518,385 stated on the cover page (in dollars after the unit check, H1), rows summing to $6,691,518,386 with VALUE read as dollars as filed, 13F file number 028-16573. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| UNITED THERAPEUTICS CORP DEL COM | 91307C102 | Stock | 2,865,000 | $796,727,850 | dollars as filed | |
| HORIZON THERAPEUTICS PLC | G46188101 | SHS | 7,000,000 | $796,600,000 | dollars as filed | |
| APELLIS PHARMACEUTICALS INC | 03753U106 | COM | 10,625,000 | $549,418,750 | dollars as filed | |
| MADRIGAL PHARMACEUTICALS INC COM | 558868105 | Stock | 1,660,000 | $481,815,000 | dollars as filed | |
| ARGENX SE SPONSORED ADR | 04016X101 | ADR | 1,265,555 | $479,430,201 | dollars as filed | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 3,175,000 | $411,416,500 | dollars as filed | |
| ASCENDIS PHARMA A/S DKK 1.0 AD | 04351P101 | SPONSORED ADR | 3,100,000 | $378,603,000 | dollars as filed | |
| BIOMARIN PHARMACEUTICAL INC | 09061G101 | COM | 3,555,555 | $367,964,387 | dollars as filed | |
| AMICUS THERAPEUTICS INC | 03152W109 | COM | 26,800,000 | $327,228,000 | dollars as filed | |
| ALNYLAM PHARMACEUTICALS INC COM | 02043Q107 | Stock | 1,105,000 | $262,603,250 | dollars as filed | |
| MIRATI THERAPEUTICS INC | 60468T105 | COM | 5,555,555 | $251,722,197 | dollars as filed | |
| SEAGEN INC | 81181C104 | COM | 1,885,000 | $242,241,350 | dollars as filed | |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 4,900,000 | $193,207,000 | dollars as filed | |
| IVERIC BIO INC | 46583P102 | COM | 6,750,000 | $144,517,500 | dollars as filed | |
| KRYSTAL BIOTECH INC COM | 501147102 | Stock | 1,410,000 | $111,700,200 | dollars as filed | |
| BIOCRYST PHARMACEUTICALS INC COM | 09058V103 | Stock | 9,050,000 | $103,894,000 | dollars as filed | |
| KYMERA THERAPEUTICS INC | 501575104 | COM | 3,850,000 | $96,096,000 | dollars as filed | |
| DICE THERAPEUTICS INC | 23345J104 | COM | 2,525,555 | $78,797,316 | dollars as filed | |
| SYNDAX PHARMACEUTICALS INC | 87164F105 | COM | 2,650,000 | $67,442,500 | dollars as filed | |
| CYMABAY THERAPEUTICS INC | 23257D103 | COM | 10,300,000 | $64,581,000 | dollars as filed | |
| MANNKIND CORP COM NEW | 56400P706 | Stock | 9,100,000 | $47,957,000 | dollars as filed | |
| NUVALENT INC COM | 670703107 | Stock | 1,555,555 | $46,324,428 | dollars as filed | |
| AVIDITY BIOSCIENCES INC COM | 05370A108 | Stock | 2,050,000 | $45,489,500 | dollars as filed | |
| IOVANCE BIOTHERAPEUTICS INC | 462260100 | COM | 7,020,000 | $44,857,800 | dollars as filed | |
| Mersana Therapeutics Inc | 59045L106 | Common Stock | 7,550,000 | $44,243,000 | dollars as filed | |
| KURA ONCOLOGY INC COM | 50127T109 | Stock | 3,105,000 | $38,533,050 | dollars as filed | |
| WHITEHAWK THERAPEUTICS INC | 00032Q104 | CMN | 2,849,402 | $36,557,828 | dollars as filed | |
| ULTRAGENYX PHARMACEUTICAL IN | 90400D108 | COM | 750,000 | $34,747,500 | dollars as filed | |
| MONTE ROSA THERAPEUTICS INC | 61225M102 | COM | 4,325,000 | $32,913,250 | dollars as filed | |
| PMV PHARMACEUTICALS INC | 69353Y103 | COM | 3,060,000 | $26,622,000 | dollars as filed | |
| DESIGN THERAPEUTICS INC | 25056L103 | COM | 2,272,222 | $23,312,998 | dollars as filed | |
| AMYLYX PHARMACEUTICALS INC | 03237H101 | COM | 630,000 | $23,278,500 | dollars as filed | |
| MARINUS PHARMACEUTICALS INC | 56854Q200 | COM NEW | 3,150,000 | $12,537,000 | dollars as filed | |
| TANGO THERAPEUTICS INC | 87583X109 | COM | 1,640,000 | $11,890,000 | dollars as filed | |
| FENNEC PHARMACEUTICALS INC | 31447P100 | COMMON STOCK | 1,200,000 | $11,520,000 | dollars as filed | |
| IO BIOTECH INC | 449778109 | COM | 2,055,883 | $4,728,531 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001104659-23-020884 | this filing | 2023-02-14 | acceptance time not in the bulk data set |