13F-HR filed by Tekla Capital Management LLC
Tekla Capital Management LLC filed this 13F-HR for the quarter ended 2022-03-31, filed 2022-05-13, with 175 holding rows worth $2,847,415,000.
- Accession
- 0001104659-22-060040
- Filer
- CIK 1300336
- Filed
- 2022-05-13
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q1 2022
A holdings report, 175 entries on the cover page, a total value of $2,847,415,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $2,847,411,000 with VALUE read as thousands by filing date, 13F file number 028-10950. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| UnitedHealth Group Inc | 91324P102 | COM | 330,026 | $168,303,000 | thousands by filing date | |
| Amgen Inc. | 031162100 | COM | 574,918 | $139,027,000 | thousands by filing date | |
| REGENERON PHARMACEUTICALS COM | 75886F107 | Stock | 146,200 | $102,109,000 | thousands by filing date | |
| HORIZON THERAPEUTICS PLC | G46188101 | SHS | 959,439 | $100,943,000 | thousands by filing date | |
| Gilead Sciences,Inc. | 375558103 | COM | 1,686,565 | $100,266,000 | thousands by filing date | |
| Johnson & Johnson | 478160104 | COM | 516,652 | $91,566,000 | thousands by filing date | |
| AbbVie,Inc. | 00287Y109 | COM | 548,144 | $88,860,000 | thousands by filing date | |
| Vertex Pharmaceuticals Incorporated | 92532F100 | COM | 308,884 | $80,609,000 | thousands by filing date | |
| ILLUMINA INC | 452327109 | COM | 226,212 | $79,038,000 | thousands by filing date | |
| Abbott Laboratories | 002824100 | COM | 618,777 | $73,238,000 | thousands by filing date | |
| ASTRAZENECA PLC SPONSORED ADR | 046353108 | ADR | 990,675 | $65,721,000 | thousands by filing date | |
| MCKESSON CORP COM | 58155Q103 | Stock | 206,022 | $63,070,000 | thousands by filing date | |
| Pfizer Inc. | 717081103 | COM | 1,171,903 | $60,669,000 | thousands by filing date | |
| Eli Lilly and Company | 532457108 | COM | 211,832 | $60,662,000 | thousands by filing date | |
| Stryker Corporation | 863667101 | COM | 225,678 | $60,335,000 | thousands by filing date | |
| Thermo Fisher Scientific Inc. | 883556102 | COM | 97,605 | $57,650,000 | thousands by filing date | |
| MODERNA INC | 60770K107 | COM | 328,524 | $56,592,000 | thousands by filing date | |
| Bristol-Myers Squibb Company | 110122108 | COM | 723,876 | $52,865,000 | thousands by filing date | |
| Medtronic Plc | G5960L103 | COM | 435,140 | $48,279,000 | thousands by filing date | |
| SEAGEN INC | 81181C104 | COM | 330,561 | $47,617,000 | thousands by filing date | |
| Merck & Co.,Inc. | 58933Y105 | COM | 575,622 | $47,230,000 | thousands by filing date | |
| Danaher Corporation | 235851102 | COM | 150,145 | $44,042,000 | thousands by filing date | |
| Cigna Corporation | 125523100 | COM | 172,023 | $41,218,000 | thousands by filing date | |
| IDEXX LABS INC COM | 45168D104 | Stock | 61,217 | $33,489,000 | thousands by filing date | |
| MOLINA HEALTHCARE INC | 60855R100 | COM | 94,525 | $31,533,000 | thousands by filing date | |
| HCA Healthcare Inc | 40412C101 | COM | 124,303 | $31,153,000 | thousands by filing date | |
| SYNEOS HEALTH INC | 87166B102 | CL A | 381,570 | $30,888,000 | thousands by filing date | |
| BIOGEN INC COM | 09062X103 | Stock | 135,639 | $28,566,000 | thousands by filing date | |
| HUMANA INC COM | 444859102 | Stock | 63,560 | $27,659,000 | thousands by filing date | |
| ZOETIS INC CL A | 98978V103 | Stock | 141,167 | $26,623,000 | thousands by filing date | |
| ALNYLAM PHARMACEUTICALS INC COM | 02043Q107 | Stock | 158,606 | $25,899,000 | thousands by filing date | |
| Boston Scientific Corporation | 101137107 | COM | 569,398 | $25,219,000 | thousands by filing date | |
| GUARDANT HEALTH INC COM | 40131M109 | Stock | 351,484 | $23,282,000 | thousands by filing date | |
| IQVIA HLDGS INC COM | 46266C105 | Stock | 98,154 | $22,694,000 | thousands by filing date | |
| JAZZ PHARMACEUTICALS PLC SHS USD | G50871105 | Stock | 140,473 | $21,867,000 | thousands by filing date | |
| ICON PUB LTD CO SHS | G4705A100 | Stock | 88,237 | $21,461,000 | thousands by filing date | |
| EDWARDS LIFESCIENCES CORP COM | 28176E108 | Stock | 177,188 | $20,859,000 | thousands by filing date | |
| BECTON DICKINSON & CO | 075887109 | COM | 73,930 | $19,665,000 | thousands by filing date | |
| WELLTOWER INC COM | 95040Q104 | REIT | 203,083 | $19,524,000 | thousands by filing date | |
| DEXCOM INC COM | 252131107 | Stock | 36,671 | $18,761,000 | thousands by filing date | |
| ZIMMER BIOMET HOLDINGS INC COM | 98956P102 | Stock | 142,044 | $18,167,000 | thousands by filing date | |
| INTRA-CELLULAR THERAPIES INC | 46116X101 | COMMON STOCK | 290,936 | $17,802,000 | thousands by filing date | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 227,697 | $17,788,000 | thousands by filing date | |
| CHARLES RIV LABS INTL INC | 159864107 | COM | 61,990 | $17,603,000 | thousands by filing date | |
| Intuitive Surgical,Inc. | 46120E602 | COM | 57,606 | $17,379,000 | thousands by filing date | |
| RESMED INC COM | 761152107 | Stock | 70,999 | $17,218,000 | thousands by filing date | |
| NOVO-NORDISK A S ADR | 670100205 | ADR | 153,523 | $17,049,000 | thousands by filing date | |
| BIONTECH SE SPONSORED ADS | 09075V102 | ADR | 95,042 | $16,210,000 | thousands by filing date | |
| Health Care Select Sector SPDR Fund | 81369Y209 | SHS | 113,230 | $15,511,000 | thousands by filing date | |
| VENTAS INC COM | 92276F100 | REIT | 248,131 | $15,325,000 | thousands by filing date | |
| RALLYBIO CORP | 75120L100 | COM | 2,195,010 | $15,321,000 | thousands by filing date | |
| CVS Health Corporation | 126650100 | COM | 147,453 | $14,924,000 | thousands by filing date | |
| UNITED THERAPEUTICS CORP DEL COM | 91307C102 | Stock | 72,206 | $12,954,000 | thousands by filing date | |
| KARUNA THERAPEUTICS INC | 48576A100 | COM | 100,458 | $12,737,000 | thousands by filing date | |
| ACCENDRA HEALTH INC | 690732102 | COM | 288,167 | $12,685,000 | thousands by filing date | |
| ARGENX SE SPONSORED ADR | 04016X101 | ADR | 38,456 | $12,126,000 | thousands by filing date | |
| NOVARTIS AG SPONSORED ADR | 66987V109 | ADR | 136,225 | $11,954,000 | thousands by filing date | |
| NEUROCRINE BIOSCIENCES INC | 64125C109 | COM | 124,609 | $11,682,000 | thousands by filing date | |
| LABORATORY CORP OF AMERICA | 50540R409 | COM NEW | 44,142 | $11,638,000 | thousands by filing date | |
| ULTRAGENYX PHARMACEUTICAL IN | 90400D108 | COM | 140,726 | $10,220,000 | thousands by filing date | |
| APELLIS PHARMACEUTICALS INC | 03753U106 | COM | 195,820 | $9,950,000 | thousands by filing date | |
| BIOMARIN PHARMACEUTICAL INC | 09061G101 | COM | 128,004 | $9,869,000 | thousands by filing date | |
| BEONE MEDICINES LTD SPONSORED ADS | 07725L102 | ADR | 51,018 | $9,622,000 | thousands by filing date | |
| OMEGA HEALTHCARE INVS INC COM | 681936100 | REIT | 306,433 | $9,548,000 | thousands by filing date | |
| UNIQURE NV | N90064101 | SHS | 521,693 | $9,427,000 | thousands by filing date | |
| AGILENT TECHNOLOGIES INC COM | 00846U101 | Stock | 66,845 | $8,846,000 | thousands by filing date | |
| WATERS CORP COM | 941848103 | Stock | 28,461 | $8,834,000 | thousands by filing date | |
| MEDICAL PROPERTIES TRUST INC COM | 58463J304 | REIT | 411,743 | $8,704,000 | thousands by filing date | |
| PHYSICIANS REALTY TRUST | 71943U104 | COM | 495,733 | $8,695,000 | thousands by filing date | |
| SPDR SER TR | 78464A870 | S&P BIOTECH | 95,649 | $8,597,000 | thousands by filing date | |
| BIOHAVEN PHARMACEUTICAL HOLDIN | G11196105 | COM | 70,176 | $8,321,000 | thousands by filing date | |
| ALIGN TECHNOLOGY INC COM | 016255101 | Stock | 18,894 | $8,238,000 | thousands by filing date | |
| ASCENDIS PHARMA A/S DKK 1.0 AD | 04351P101 | SPONSORED ADR | 67,794 | $7,956,000 | thousands by filing date | |
| ADDUS HOMECARE CORP | 006739106 | COM | 83,632 | $7,802,000 | thousands by filing date | |
| SABRA HEALTH CARE REIT INC COM | 78573L106 | REIT | 510,660 | $7,604,000 | thousands by filing date | |
| Elevance Health, Inc. | 036752103 | COM | 14,644 | $7,193,000 | thousands by filing date | |
| DENALI THERAPEUTICS INC COM | 24823R105 | Stock | 222,420 | $7,155,000 | thousands by filing date | |
| LTC PPTYS INC COM | 502175102 | REIT | 182,293 | $7,013,000 | thousands by filing date | |
| HEALTHEQUITY INC COM | 42226A107 | Stock | 103,314 | $6,967,000 | thousands by filing date | |
| MIRATI THERAPEUTICS INC | 60468T105 | COM | 83,784 | $6,889,000 | thousands by filing date | |
| IONIS PHARMACEUTICALS INC COM | 462222100 | Stock | 175,680 | $6,507,000 | thousands by filing date | |
| CARIBOU BIOSCIENCES INC COM | 142038108 | Stock | 699,377 | $6,420,000 | thousands by filing date | |
| AMN HEALTHCARE SVCS INC | 001744101 | COM | 61,201 | $6,385,000 | thousands by filing date | |
| TRAVERE THERAPEUTICS INC | 89422G107 | COM | 247,678 | $6,383,000 | thousands by filing date | |
| SANOFI SA SPONSORED ADR | 80105N105 | ADR | 123,454 | $6,338,000 | thousands by filing date | |
| BLUEPRINT MEDICINES CORP | 09627Y109 | COM | 97,253 | $6,213,000 | thousands by filing date | |
| ARROWHEAD PHARMACEUTICALS IN | 04280A100 | COM | 134,812 | $6,200,000 | thousands by filing date | |
| REVVITY INC | 714046109 | COM | 33,444 | $5,835,000 | thousands by filing date | |
| SMITH & NEPHEW PLC SPDN ADR NEW | 83175M205 | ADR | 181,710 | $5,797,000 | thousands by filing date | |
| ARVINAS INC | 04335A105 | COM | 85,997 | $5,788,000 | thousands by filing date | |
| R1 RCM INC | 749397105 | COM | 202,351 | $5,415,000 | thousands by filing date | |
| QIAGEN NV | N72482123 | SHS NEW | 107,855 | $5,285,000 | thousands by filing date | |
| HEALTHPEAK PROPERTIES INC COM | 42250P103 | REIT | 150,392 | $5,163,000 | thousands by filing date | |
| KONINKLIJKE PHILIPS N V NY REGIS SHS NEW | 500472303 | ADR | 164,790 | $5,031,000 | thousands by filing date | |
| ALKERMES PLC | G01767105 | SHS | 190,122 | $5,002,000 | thousands by filing date | |
| ACADIA HEALTHCARE COMPANY INC COM | 00404A109 | Stock | 72,307 | $4,738,000 | thousands by filing date | |
| NOVAVAX INC | 670002401 | COM NEW | 63,800 | $4,699,000 | thousands by filing date | |
| ADAPTIVE BIOTECHNOLOGIES CORP COM | 00650F109 | Stock | 337,722 | $4,688,000 | thousands by filing date | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 119,898 | $4,413,000 | thousands by filing date | |
| TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS | 881624209 | ADR | 459,651 | $4,316,000 | thousands by filing date | |
| INTELLIA THERAPEUTICS INC | 45826J105 | COM | 58,180 | $4,228,000 | thousands by filing date | |
| STERIS PLC SHS USD | G8473T100 | Stock | 16,669 | $4,030,000 | thousands by filing date | |
| VERONA PHARMA PLC | 925050106 | SPONSORED ADS | 751,905 | $3,752,000 | thousands by filing date | |
| VECTIVBIO HLDG AG | H9060V101 | COM | 756,502 | $3,556,000 | thousands by filing date | |
| CRISPR THERAPEUTICS AG NAMEN AKT | H17182108 | Stock | 55,080 | $3,457,000 | thousands by filing date | |
| G1 THERAPEUTICS INC | 3621LQ109 | COM | 423,869 | $3,221,000 | thousands by filing date | |
| BIOCRYST PHARMACEUTICALS INC COM | 09058V103 | Stock | 196,625 | $3,197,000 | thousands by filing date | |
| TAKEDA PHARMACEUTICAL CO LTD SPONSORED ADS | 874060205 | ADR | 210,146 | $3,009,000 | thousands by filing date | |
| XENCOR INC | 98401F105 | COMMON STOCK | 112,673 | $3,006,000 | thousands by filing date | |
| PROTAGONIST THERAPEUTICS | 74366E102 | COM | 122,271 | $2,895,000 | thousands by filing date | |
| HEALTHCARE RLTY TR | 421946104 | COM | 104,024 | $2,859,000 | thousands by filing date | |
| GLOBAL MED REIT INC | 37954A204 | COM NEW | 174,897 | $2,854,000 | thousands by filing date | |
| DENTSPLY SIRONA INC | 24906P109 | COM | 57,400 | $2,825,000 | thousands by filing date | |
| MOONLAKE IMMUNOTHERAPEUTICS | G4444C102 | COM | 250,000 | $2,775,000 | thousands by filing date | |
| NOVABRIDGE BIOSCIENCES | 44975P103 | CMN | 162,580 | $2,640,000 | thousands by filing date | |
| PYXIS ONCOLOGY INC COMMON STOCK | 747324101 | Stock | 708,303 | $2,630,000 | thousands by filing date | |
| CEREVEL THERAPEUTICS HLDNG I | 15678U128 | COM | 73,681 | $2,580,000 | thousands by filing date | |
| AFFIMED N V | N01045108 | COM | 586,038 | $2,561,000 | thousands by filing date | |
| ARCUTIS BIOTHERAPEUTICS INC | 03969K108 | COM | 131,633 | $2,535,000 | thousands by filing date | |
| MERUS N V | N5749R100 | COM | 95,290 | $2,519,000 | thousands by filing date | |
| HEALTHCARE | 42225P501 | CL A NEW | 70,662 | $2,215,000 | thousands by filing date | |
| HOLOGIC INC | 436440101 | COM | 28,347 | $2,178,000 | thousands by filing date | |
| GALERA THERAPEUTICS EQUICLASS EQUITY | 36338D108 | COMMON STOCK | 898,374 | $2,138,000 | thousands by filing date | |
| AURINIA PHARMACEUTICALS INC COM | 05156V102 | Stock | 162,599 | $2,013,000 | thousands by filing date | |
| PERRIGO CO PLC SHS | G97822103 | Stock | 51,224 | $1,969,000 | thousands by filing date | |
| CHEMOCENTRYX INC | 16383L106 | COM | 78,197 | $1,960,000 | thousands by filing date | |
| ZAI LAB LTD ADR | 98887Q104 | ADR | 43,300 | $1,904,000 | thousands by filing date | |
| FULCRUM THERAPEUTICS INC | 359616109 | COMMON STOCK | 77,293 | $1,828,000 | thousands by filing date | |
| ACADIA PHARMACEUTICALS INC | 004225108 | COM | 72,225 | $1,749,000 | thousands by filing date | |
| MEREO BIOPHARMA GROUP PLC | 589492107 | CMN | 1,551,082 | $1,737,000 | thousands by filing date | |
| MEDPACE HLDGS INC COM | 58506Q109 | Stock | 9,435 | $1,543,000 | thousands by filing date | |
| STEVANATO GROUP S P A ORD SHS | T9224W109 | Stock | 71,190 | $1,432,000 | thousands by filing date | |
| MORPHIC HLDG INC | 61775R105 | COM | 35,025 | $1,406,000 | thousands by filing date | |
| SCHOLAR ROCK HLDG CORP | 80706P103 | COM | 108,833 | $1,403,000 | thousands by filing date | |
| ITEOS THERAPEUTICS INC | 46565G104 | COM | 42,362 | $1,363,000 | thousands by filing date | |
| SUTRO BIOPHARMA INC | 869367102 | COM | 163,924 | $1,347,000 | thousands by filing date | |
| HARPOON THERAPEUTICS INC | 41358P106 | COM | 259,910 | $1,292,000 | thousands by filing date | |
| ADICET BIO INC | 007002108 | COM | 63,329 | $1,265,000 | thousands by filing date | |
| FATE THERAPEUTICS INC | 31189P102 | COM | 31,652 | $1,227,000 | thousands by filing date | |
| ASSERTIO HOLDINGS INC | 04546C205 | COM NEW | 410,575 | $1,178,000 | thousands by filing date | |
| THESEUS PHARMACEUTICALS INC | 88369M101 | COM | 100,000 | $1,153,000 | thousands by filing date | |
| DIVERSIFIED HEALTHCARE TR | 25525P107 | COM SH BEN INT | 357,720 | $1,145,000 | thousands by filing date | |
| ENDO INTL PLC | G30401106 | SHS | 494,607 | $1,143,000 | thousands by filing date | |
| ALX ONCOLOGY HOLDINGS INC | 00166B105 | COMMON STOCK | 66,211 | $1,119,000 | thousands by filing date | |
| DESIGN THERAPEUTICS INC | 25056L103 | COM | 65,351 | $1,055,000 | thousands by filing date | |
| COMMUNITY HEALTH SYSTEMS INC | 203668108 | COMMON STOCK | 88,335 | $1,049,000 | thousands by filing date | |
| SYNDAX PHARMACEUTICALS INC | 87164F105 | COM | 56,480 | $982,000 | thousands by filing date | |
| BEAM THERAPEUTICS INC | 07373V105 | COM | 15,817 | $906,000 | thousands by filing date | |
| INTERCEPT PHARMACEUTICALS IN | 45845P108 | COM | 52,067 | $847,000 | thousands by filing date | |
| PROMETHEUS BIOSCIENCES INC | 74349U108 | COM | 22,115 | $835,000 | thousands by filing date | |
| PRAXIS PRECISION MEDICINES I | 74006W108 | COM | 75,000 | $766,000 | thousands by filing date | |
| PRECISION BIOSCIENCES INC | 74019P108 | COM | 224,534 | $692,000 | thousands by filing date | |
| UNIVERSAL HEALTH RLTY INCOME | 91359E105 | REIT | 11,258 | $657,000 | thousands by filing date | |
| COMMUNITY USD0.01 | 20369C106 | COM | 14,900 | $629,000 | thousands by filing date | |
| NATIONAL HEALTH INVS INC COM | 63633D104 | REIT | 10,038 | $592,000 | thousands by filing date | |
| EDGEWISE THERAPEUTICS INC | 28036F105 | COM | 60,550 | $587,000 | thousands by filing date | |
| UNIVERSAL HLTH SVCS INC CL B | 913903100 | Stock | 4,000 | $580,000 | thousands by filing date | |
| ARDELYX INC | 039697107 | COM | 539,408 | $577,000 | thousands by filing date | |
| Tscan Therapeutics Inc | 89854M101 | COM | 200,000 | $560,000 | thousands by filing date | |
| MORPHOSYS AG | 617760202 | ADR | 81,867 | $555,000 | thousands by filing date | |
| AVIDITY BIOSCIENCES INC COM | 05370A108 | Stock | 26,452 | $489,000 | thousands by filing date | |
| BICYCLE THERAPEUTICS PLC-ADR | 088786108 | SPONSORED ADS | 10,086 | $443,000 | thousands by filing date | |
| REPARE THERAPEUTICS INC | 760273102 | COM | 29,150 | $415,000 | thousands by filing date | |
| BLACK DIAMOND THERAPEUTICS I | 09203E105 | COM | 131,990 | $366,000 | thousands by filing date | |
| 1LIFE HEALTHCARE INC | 68269G107 | COM | 31,266 | $346,000 | thousands by filing date | |
| FUSION PHARMACEUTICALS INC | 36118A100 | COM | 43,394 | $337,000 | thousands by filing date | |
| NKARTA INC | 65487U108 | COMMON STOCK | 28,988 | $330,000 | thousands by filing date | |
| ZIMVIE INC | 98888T107 | COM | 14,202 | $324,000 | thousands by filing date | |
| SPECTRUM PHARMACEUTICALS INC | 84763A108 | COM | 114,670 | $148,000 | thousands by filing date | |
| VYNE THERAP. | 92941V209 | COM | 135,395 | $88,000 | thousands by filing date | |
| CORBUS PHARMACEUTICALS HLDGS | 21833P103 | COM | 154,310 | $82,000 | thousands by filing date | |
| ORUKA THERAPEUTICS INC COM | 00211Y506 | Stock | 32,461 | $75,000 | thousands by filing date | |
| FIVE STAR SENIOR LIVING INC | 33832D205 | COM NEW | 24,237 | $52,000 | thousands by filing date | |
| BELLICUM PHARMACEUTICALS INC COM NEW | 079481404 | Stock | 6,000 | $13,000 | thousands by filing date | |
| NEXGEL INC | 65344E107 | COM | 4,243 | $8,000 | thousands by filing date |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001104659-22-060040 | this filing | 2022-05-13 | acceptance time not in the bulk data set |