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13F-HR filed by Avoro Capital Advisors LLC

Avoro Capital Advisors LLC filed this 13F-HR for the quarter ended 2021-09-30, filed 2021-11-15, with 47 holding rows worth $6,366,047,000.

Accession
0001104659-21-138678
Filed
2021-11-15
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q3 2021

A holdings report, 52 entries on the cover page, a total value of $6,366,047,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $6,366,047,000 with VALUE read as thousands by filing date, 13F file number 028-16573. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
HORIZON THERAPEUTICS PLCG46188101SHS9,000,000$985,860,000thousands by filing date
MIRATI THERAPEUTICS INC60468T105COM5,000,000$884,550,000thousands by filing date
ACCELERON PHARMA INC00434H108COM4,000,000$688,400,000thousands by filing date
UNITED THERAPEUTICS CORP DEL COM91307C102Stock3,000,000$553,740,000thousands by filing date
ASCENDIS PHARMA A/S DKK 1.0 AD04351P101SPONSORED ADR1,980,000$315,592,000thousands by filing date
ARGENX SE SPONSORED ADR04016X101ADR946,500$285,843,000thousands by filing date
SAREPTA THERAPEUTICS INC803607100COM2,500,000$231,200,000thousands by filing date
IOVANCE BIOTHERAPEUTICS INC462260100COM8,500,000$209,610,000thousands by filing date
ARENA PHARMACEUTICALS INC040047607COM NEW3,425,000$203,959,000thousands by filing date
AMICUS THERAPEUTICS INC03152W109COM17,679,273$168,837,000thousands by filing date
APELLIS PHARMACEUTICALS INC03753U106COM5,000,000$164,800,000thousands by filing date
ALNYLAM PHARMACEUTICALS INC COM02043Q107Stock850,000$160,489,000thousands by filing date
BIOMARIN PHARMACEUTICAL INC09061G101COM1,875,000$144,919,000thousands by filing date
Vertex Pharmaceuticals Incorporated92532F100COM664,000$120,443,000thousands by filing date
IVERIC BIO INC46583P102COM7,100,000$115,304,000thousands by filing date
MADRIGAL PHARMACEUTICALS INC COM558868105Stock1,425,000$113,701,000thousands by filing date
TRILLIUM THERAPEUTICS INC COM NEW89620X506Stock5,700,000$100,092,000thousands by filing date
PMV PHARMACEUTICALS INC69353Y103COM2,925,000$87,165,000thousands by filing date
KURA ONCOLOGY INC COM50127T109Stock4,000,000$74,920,000thousands by filing date
Mersana Therapeutics Inc59045L106Common Stock6,800,000$64,124,000thousands by filing date
MONTE ROSA THERAPEUTICS INC61225M102COM3,311,434$61,003,000thousands by filing date
XENON PHARMACEUTICALS INC COM98420N105Stock3,650,000$55,772,000thousands by filing date
WHITEHAWK THERAPEUTICS INC00032Q104CMN1,829,402$53,730,000thousands by filing date
MANNKIND CORP COM NEW56400P706Stock8,800,000$38,280,000thousands by filing date
CYMABAY THERAPEUTICS INC23257D103COM10,300,000$37,595,000thousands by filing date
MARINUS PHARMACEUTICALS INC56854Q200COM NEW3,235,000$36,814,000thousands by filing date
ACADIA PHARMACEUTICALS INC004225108COM2,200,000$36,542,000thousands by filing date
DECIPHERA PHARMACEUTICALS IN24344T101COM1,068,000$36,291,000thousands by filing date
AMARIN CORP PLC023111206SPONS ADR NEW6,000,000$30,600,000thousands by filing date
PRAXIS PRECISION MEDICINES I74006W108COM1,600,000$29,584,000thousands by filing date
SYNDAX PHARMACEUTICALS INC87164F105COM1,545,000$29,525,000thousands by filing date
AVIDITY BIOSCIENCES INC COM05370A108Stock1,150,000$28,325,000thousands by filing date
KYMERA THERAPEUTICS INC501575104COM455,750$26,771,000thousands by filing date
DICE THERAPEUTICS INC23345J104COM800,000$26,200,000thousands by filing date
BIOGEN INC COM09062X103Stock84,000$23,771,000thousands by filing date
AVADEL PHARMACEUTICALS, PLC05337M104COMMON STOCK-FO2,275,000$22,295,000thousands by filing date
NUVALENT INC COM670703107Stock1,257,671$22,288,000thousands by filing date
DESIGN THERAPEUTICS INC25056L103COM1,468,318$21,570,000thousands by filing date
TANGO THERAPEUTICS INC87583X109COM1,550,000$20,042,000thousands by filing date
FENNEC PHARMACEUTICALS INC31447P100COMMON STOCK1,670,000$15,731,000thousands by filing date
Adverum Biotechnologies, Inc.00773U108Common Stock6,950,000$15,082,000thousands by filing date
MERUS N VN5749R100COM450,000$9,900,000thousands by filing date
GENOCEA BIOSCIENCES INC372427401COMMON STOCK5,084,184$9,762,000thousands by filing date
SAREPTA THERAPEUTICS INC803607100COM200,000$2,194,000thousands by filing datecall
IOVANCE BIOTHERAPEUTICS INC462260100COM650,000$1,540,000thousands by filing datecall
APELLIS PHARMACEUTICALS INC03753U106COM1,515,000$1,260,000thousands by filing datecall
ACCELERON PHARMA INC00434H108COM476,100$32,000thousands by filing datecall

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001104659-21-138678this filing2021-11-15acceptance time not in the bulk data set