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13F-HR filed by Avoro Capital Advisors LLC

Avoro Capital Advisors LLC filed this 13F-HR for the quarter ended 2021-03-31, filed 2021-05-17, with 46 holding rows worth $5,790,264,000.

Accession
0001104659-21-067522
Filed
2021-05-17
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q1 2021

A holdings report, 46 entries on the cover page, a total value of $5,790,264,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $5,790,264,000 with VALUE read as thousands by filing date, 13F file number 028-16573. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
HORIZON THERAPEUTICS PLCG46188101SHS9,000,000$828,360,000thousands by filing date
MIRATI THERAPEUTICS INC60468T105COM4,675,000$800,828,000thousands by filing date
UNITED THERAPEUTICS CORP DEL COM91307C102Stock3,000,000$501,810,000thousands by filing date
ACCELERON PHARMA INC00434H108COM3,000,000$406,830,000thousands by filing date
Vertex Pharmaceuticals Incorporated92532F100COM1,400,000$300,846,000thousands by filing date
ARENA PHARMACEUTICALS INC040047607COM NEW4,050,000$281,030,000thousands by filing date
ARGENX SE SPONSORED ADR04016X101ADR925,500$254,873,000thousands by filing date
IOVANCE BIOTHERAPEUTICS INC462260100COM8,000,000$253,280,000thousands by filing date
ASCENDIS PHARMA043351P10Sponsored ADR1,900,000$244,872,000thousands by filing date
MADRIGAL PHARMACEUTICALS INC COM558868105Stock1,425,000$166,682,000thousands by filing date
SAREPTA THERAPEUTICS INC803607100COM2,150,000$160,240,000thousands by filing date
BIOMARIN PHARMACEUTICAL INC09061G101COM1,650,000$124,592,000thousands by filing date
AMICUS THERAPEUTICS INC03152W109COM12,250,000$121,030,000thousands by filing date
KURA ONCOLOGY INC COM50127T109Stock4,000,000$113,080,000thousands by filing date
Mersana Therapeutics Inc59045L106Common Stock6,800,000$110,024,000thousands by filing date
Adverum Biotechnologies, Inc.00773U108Common Stock8,000,000$78,880,000thousands by filing date
PMV PHARMACEUTICALS INC69353Y103COM2,360,267$77,629,000thousands by filing date
CONSTELLATION PHARMACEUTICALS INC.210373106Common Stock2,950,000$69,001,000thousands by filing date
XENON PHARMACEUTICALS INC COM98420N105Stock3,650,000$65,335,000thousands by filing date
ACADIA PHARMACEUTICALS INC004225108COM2,500,000$64,500,000thousands by filing date
TRILLIUM THERAPEUTICS INC COM NEW89620X506Stock5,700,000$61,218,000thousands by filing date
SYNDAX PHARMACEUTICALS INC87164F105COM2,500,000$55,900,000thousands by filing date
RELMADA THERAPEUTICS INC75955J402COMMON STOCK1,525,000$53,695,000thousands by filing date
MARINUS PHARMACEUTICALS INC56854Q200COM NEW3,235,000$50,078,000thousands by filing date
PRAXIS PRECISION MEDICINES I74006W108COM1,596,495$47,441,000thousands by filing date
CYMABAY THERAPEUTICS INC23257D103COM10,300,000$46,762,000thousands by filing date
IVERIC BIO INC46583P102COM7,250,000$44,805,000thousands by filing date
APELLIS PHARMACEUTICALS INC03753U106COM1,000,000$42,910,000thousands by filing date
DECIPHERA PHARMACEUTICALS IN24344T101COM893,000$40,042,000thousands by filing date
DESIGN THERAPEUTICS INC25056L103COM1,468,318$39,702,000thousands by filing date
AVADEL PHARMACEUTICALS, PLC05337M104COMMON STOCK-FO4,365,000$39,460,000thousands by filing date
AMARIN CORP PLC023111206SPONS ADR NEW6,000,000$37,260,000thousands by filing date
TRAVERE THERAPEUTICS INC89422G107COM1,249,000$31,188,000thousands by filing date
MANNKIND CORP COM NEW56400P706Stock7,500,000$29,400,000thousands by filing date
OLEMA PHARMACEUTICALS INC68062P106COM876,986$24,599,000thousands by filing date
ADAPTIMMUNE THERAPEUTICS PLC00653A107SPONDS ADR3,550,000$18,851,000thousands by filing date
RELAY THERAPEUTICS INC COM75943R102Stock500,000$17,285,000thousands by filing date
MERUS N VN5749R100COM665,000$13,892,000thousands by filing date
GENOCEA BIOSCIENCES INC372427401COMMON STOCK5,084,184$13,778,000thousands by filing date
AVIDITY BIOSCIENCES INC COM05370A108Stock545,000$11,886,000thousands by filing date
BLACK DIAMOND THERAPEUTICS I09203E105COM440,000$10,674,000thousands by filing date
THERAPEUTICS ACQUISITION COR88339T103COM CL A1,000,000$10,510,000thousands by filing date
FENNEC PHARMACEUTICALS INC31447P100COMMON STOCK1,670,000$10,371,000thousands by filing date
BCTG ACQUISITION CORP05492W103COM800,000$8,896,000thousands by filing date
JOUNCE THERAPEUTICS INC481116101COM555,000$5,700,000thousands by filing date
LAKEFRONT BIOTHERAPEUTICS NV36315X101SPON ADR3,100$239,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001104659-21-067522this filing2021-05-17acceptance time not in the bulk data set