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13F-HR filed by Tekla Capital Management LLC

Tekla Capital Management LLC filed this 13F-HR for the quarter ended 2017-03-31, filed 2017-05-12, with 139 holding rows worth $2,579,194,000.

Accession
0001104659-17-032262
Filed
2017-05-12
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q1 2017

A holdings report, 139 entries on the cover page, a total value of $2,579,194,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $2,579,194,000 with VALUE read as thousands by filing date, 13F file number 028-10950. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
Gilead Sciences,Inc.375558103COM2,530,131$171,846,000thousands by filing date
CELGENE CORP151020104COM1,366,605$170,047,000thousands by filing date
BIOGEN INC COM09062X103Stock484,974$132,602,000thousands by filing date
Vertex Pharmaceuticals Incorporated92532F100COM1,033,503$113,014,000thousands by filing date
Amgen Inc.031162100COM684,824$112,359,000thousands by filing date
ALEXION PHARMACEUTICALS INC015351109COM795,905$96,496,000thousands by filing date
INCYTE CORP COM45337C102Stock693,275$92,670,000thousands by filing date
Johnson & Johnson478160104COM714,362$88,974,000thousands by filing date
Merck & Co.,Inc.58933Y105COM1,198,349$76,143,000thousands by filing date
ALLERGAN PLCG0177J108SHS310,610$74,211,000thousands by filing date
REGENERON PHARMACEUTICALS COM75886F107Stock187,666$72,722,000thousands by filing date
MYLAN NVN59465109SHS EURO1,550,412$60,451,000thousands by filing date
Abbott Laboratories002824100COM1,152,520$51,183,000thousands by filing date
ILLUMINA INC452327109COM297,360$50,742,000thousands by filing date
UnitedHealth Group Inc91324P102COM306,852$50,327,000thousands by filing date
Medtronic PlcG5960L103COM613,030$49,386,000thousands by filing date
JAZZ PHARMACEUTICALS PLC SHS USDG50871105Stock331,411$48,098,000thousands by filing date
BIOMARIN PHARMACEUTICAL INC09061G101COM505,845$44,403,000thousands by filing date
Eli Lilly and Company532457108COM493,100$41,475,000thousands by filing date
SHIRE PLC82481R106COMMON STOCK-FO231,413$40,319,000thousands by filing date
Pfizer Inc.717081103COM1,146,689$39,228,000thousands by filing date
Thermo Fisher Scientific Inc.883556102COM228,020$35,024,000thousands by filing date
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS881624209ADR1,015,758$32,596,000thousands by filing date
CVS Health Corporation126650100COM411,891$32,333,000thousands by filing date
HUMANA INC COM444859102Stock153,800$31,704,000thousands by filing date
CENCORA INC COM03073E105Stock330,687$29,266,000thousands by filing date
ISHARES TR464287556ISHARES BIOTECH77,970$22,866,000thousands by filing date
IDEXX LABS INC COM45168D104Stock132,352$20,463,000thousands by filing date
NEUROCRINE BIOSCIENCES INC64125C109COM446,074$19,315,000thousands by filing date
NOVARTIS AG SPONSORED ADR66987V109ADR248,800$18,478,000thousands by filing date
MOLINA HEALTHCARE INC60855R100COM402,541$18,356,000thousands by filing date
MCKESSON CORP COM58155Q103Stock113,100$16,768,000thousands by filing date
SPDR SER TR78464A870S&P BIOTECH226,460$15,703,000thousands by filing date
SABRA HEALTH CARE REIT INC COM78573L106REIT550,990$15,389,000thousands by filing date
SAREPTA THERAPEUTICS INC803607100COM511,600$15,143,000thousands by filing date
GLAXOSMITHKLINE PLC-ADR37733W105SPONSORED ADR359,000$15,135,000thousands by filing date
OMEGA HEALTHCARE INVS INC COM681936100REIT458,616$15,130,000thousands by filing date
PARATEK PHARMACEUTICALS INC699374302Equity762,581$14,680,000thousands by filing date
ASTRAZENECA PLC SPONSORED ADR046353108ADR463,800$14,443,000thousands by filing date
SANOFI SA SPONSORED ADR80105N105ADR305,000$13,801,000thousands by filing date
SENIOR HSG PPTYS TR81721M109SH BEN INT646,554$13,093,000thousands by filing date
MEDICAL PROPERTIES TRUST INC COM58463J304REIT1,007,717$12,989,000thousands by filing date
WELLTOWER INC 6.50 PFD PREPET95040Q203CPFD200,000$12,624,000thousands by filing date
ALNYLAM PHARMACEUTICALS INC COM02043Q107Stock243,995$12,505,000thousands by filing date
ZIMMER BIOMET HOLDINGS INC COM98956P102Stock102,300$12,492,000thousands by filing date
CIGNA CORPORATION125509109COM83,900$12,291,000thousands by filing date
EXELIXIS INC COM30161Q104Stock551,647$11,954,000thousands by filing date
MERUS N VN5749R100COM479,150$11,682,000thousands by filing date
VENTAS INC COM92276F100REIT175,991$11,446,000thousands by filing date
CHARLES RIV LABS INTL INC159864107COM127,100$11,433,000thousands by filing date
PHYSICIANS REALTY TRUST71943U104COM530,672$10,544,000thousands by filing date
Health Care Select Sector SPDR Fund81369Y209SHS140,600$10,455,000thousands by filing date
AEGERION PHARMACEUTICALS INC00767EAB8NOTE 2.000 8/113,000,000$10,400,000thousands by filing dateprincipal
CENTENE CORP DEL COM15135B101Stock144,300$10,283,000thousands by filing date
PIERIS PHARMACEUTICALS INC720795103COM3,940,084$10,244,000thousands by filing date
ENDO INTL PLCG30401106SHS914,548$10,206,000thousands by filing date
Bristol-Myers Squibb Company110122108COM186,500$10,142,000thousands by filing date
ACADIA HEALTHCARE COMPANY INC COM00404A109Stock231,200$10,080,000thousands by filing date
LAKEFRONT BIOTHERAPEUTICS NV36315X101SPON ADR115,738$9,975,000thousands by filing date
PUMA BIOTECHNOLOGY INC74587V107COMMON STOCK260,200$9,679,000thousands by filing date
CARE CAP PPTYS INC141624106COM345,022$9,271,000thousands by filing date
TETRAPHASE PHARMACEUTICALS INC88165N105COMMON STOCK1,004,322$9,230,000thousands by filing date
CYTOMX THERAPEUTICS INC23284F105COMMON STOCK530,092$9,155,000thousands by filing date
ARDELYX INC039697107COM639,370$8,088,000thousands by filing date
ADAPTIMMUNE THERAPEUTICS PLC00653A107SPONDS ADR1,466,368$8,080,000thousands by filing date
AKORN INC009728106COM327,735$7,892,000thousands by filing date
NATERA INC COM632307104Stock882,358$7,827,000thousands by filing date
KARYOPHARM THERAPEUTICS INC48576U106COM605,224$7,771,000thousands by filing date
CELLECTIS ADS15117K103COM310,250$7,446,000thousands by filing date
MOMENTA PHARMACEUTICALS INC60877T100COM504,400$6,734,000thousands by filing date
PRA HEALTH SCIENCES INC69354M108COM102,000$6,653,000thousands by filing date
LTC PPTYS INC COM502175102REIT136,212$6,525,000thousands by filing date
SAGE THERAPEUTICS INC78667J108COM90,480$6,430,000thousands by filing date
GLOBAL BLOOD THERAPEUTICS USD37890U108COM172,500$6,357,000thousands by filing date
CARDINAL HEALTH INC14149Y108COM76,600$6,247,000thousands by filing date
EPIZYME INC29428V104COM362,000$6,208,000thousands by filing date
AVADEL PHARMACEUTICALS, PLC05337M104COMMON STOCK-FO624,288$6,043,000thousands by filing date
DEXCOM INC COM252131107Stock71,200$6,033,000thousands by filing date
UNIVERSAL HLTH SVCS INC CL B913903100Stock48,180$5,996,000thousands by filing date
ULTRAGENYX PHARMACEUTICAL IN90400D108COM88,400$5,992,000thousands by filing date
UNITED THERAPEUTICS CORP DEL COM91307C102Stock43,961$5,951,000thousands by filing date
NEW SR INVT GROUP INC648691103COM567,997$5,794,000thousands by filing date
Egalet Corporation28226BAB0Note 5.50% 4/1/207,000,000$5,758,000thousands by filing dateprincipal
HCA Healthcare Inc40412C101COM63,432$5,645,000thousands by filing date
DERMIRA INC24983L104COM165,200$5,635,000thousands by filing date
EDWARDS LIFESCIENCES CORP COM28176E108Stock55,900$5,259,000thousands by filing date
MYOVANT SCIENCES LTDG637AM102COMMON STOCK-FO400,000$4,696,000thousands by filing date
FOAMIX PHARMACEUTICALS LTDM46135105SHS930,398$4,605,000thousands by filing date
BLUEBIRD BIO INC09609G100COM49,345$4,485,000thousands by filing date
ALLERGAN PLCG0177J116PFD CONV SER A5,000$4,249,000thousands by filing date
INNOVIVA INC45781M101COM248,803$3,441,000thousands by filing date
AFFIMED N VN01045108COM1,405,324$3,232,000thousands by filing date
BEONE MEDICINES LTD SPONSORED ADS07725L102ADR87,531$3,205,000thousands by filing date
GRIFOLS S A398438408SP ADR REP B NVT166,000$3,133,000thousands by filing date
RETROPHIN INC761299106COM167,949$3,100,000thousands by filing date
AMICUS THERAPEUTICS INC03152W109COM418,730$2,986,000thousands by filing date
TENET HEALTHCARE CORP COM NEW88033G407Stock164,500$2,913,000thousands by filing date
NOVO-NORDISK A S ADR670100205ADR83,000$2,845,000thousands by filing date
NABRIVA THERAPEUTICS AG62957M104SPONSORED ADR233,334$2,798,000thousands by filing date
Mallinckrodt PlcG5785G107SHS61,900$2,759,000thousands by filing date
FORWARD PHARMA A/S34986J105SPONSORED ADR122,835$2,642,000thousands by filing date
HALOZYME THERAPEUTICS INC COM40637H109Stock200,000$2,592,000thousands by filing date
PERRIGO CO PLC SHSG97822103Stock37,300$2,476,000thousands by filing date
Accelerate Diagnostics00430H102COM100,000$2,420,000thousands by filing date
HORIZON PHARMA PLCG4617B105SHS162,900$2,408,000thousands by filing date
DBV TECHNOLOGIES S A23306J101ADR65,600$2,310,000thousands by filing date
NANOSTRING TECHNOLOGIES INC63009R109COM113,500$2,255,000thousands by filing date
CIDARA THERAPEUTICS INC COM NEW171757107Stock286,472$2,234,000thousands by filing date
HEALTHCARE RLTY TR421946104COM68,000$2,210,000thousands by filing date
VALEANT PHARMACEUTICALS INTL91911K102COM192,000$2,118,000thousands by filing date
DIPLOMAT PHARMACY INC25456K101COM130,223$2,077,000thousands by filing date
DYNAVAX TECHNOLOGIES CORP268158201COM NEW345,050$2,053,000thousands by filing date
ARCA BIOPHARMA INC00211Y407COM PAR811,227$2,028,000thousands by filing date
COHERUS ONCOLOGY INC19249H103COM90,000$1,904,000thousands by filing date
COMMUNITY HEALTH SYSTEMS INC203668108COMMON STOCK203,935$1,809,000thousands by filing date
IMPAX LABORATORIES INC45256B101COM124,335$1,573,000thousands by filing date
WELLTOWER INC COM95040Q104REIT21,400$1,516,000thousands by filing date
HEALTHCARE42225P501CL A NEW46,000$1,447,000thousands by filing date
ACCELERON PHARMA INC00434H108COM54,450$1,441,000thousands by filing date
HCP INC40414L109COM45,500$1,423,000thousands by filing date
XENON PHARMACEUTICALS INC COM98420N105Stock350,000$1,400,000thousands by filing date
UNIQURE NVN90064101SHS241,021$1,393,000thousands by filing date
SPARK THERAPEUTICS INC84652J103COM24,300$1,296,000thousands by filing date
JUNO THERAPEUTICS INC48205A109COM56,900$1,263,000thousands by filing date
GENMARK DIAGNOSTICS INC372309104COM93,349$1,197,000thousands by filing date
INTELLIA THERAPEUTICS INC45826J105COM71,842$1,012,000thousands by filing date
Alliqua BioMedical Inc019621200COM NEW1,650,000$833,000thousands by filing date
BELLICUM PHARMACEUTICALS INC079481107COM60,000$740,000thousands by filing date
NOVAVAX INC670002104COMMON STOCK571,000$731,000thousands by filing date
FLEX PHARMA INC33938A105COM162,124$713,000thousands by filing date
AURIS MED HLDG AGH03579101COM774,504$712,000thousands by filing date
GLOBAL MED REIT INC37954A204COM NEW73,400$666,000thousands by filing date
VERADIGM INC01988P108COMMON STOCK47,300$600,000thousands by filing date
XENCOR INC98401F105COMMON STOCK20,000$478,000thousands by filing date
CELLDEX THERAPEUTICS INC NEW15117B103COM105,800$382,000thousands by filing date
RMR GROUP INC74967R106CL A7,441$368,000thousands by filing date
QUORUM HEALTH CORP74909E106COM23,725$129,000thousands by filing date
ZAFGEN INC98885E103COM13,307$62,000thousands by filing date
AbbVie,Inc.00287Y109COM156$10,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001104659-17-032262this filing2017-05-12acceptance time not in the bulk data set