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13F-HR filed by Tekla Capital Management LLC

Tekla Capital Management LLC filed this 13F-HR for the quarter ended 2015-06-30, filed 2015-08-12, with 116 holding rows worth $2,764,069,000.

Accession
0001104659-15-058926
Filed
2015-08-12
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q2 2015

A holdings report, 116 entries on the cover page, a total value of $2,764,069,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $2,764,069,000 with VALUE read as thousands by filing date, 13F file number 028-10950. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
Gilead Sciences,Inc.375558103COM2,079,731$243,495,000thousands by filing date
CELGENE CORP151020104COM1,929,234$223,280,000thousands by filing date
BIOGEN INC COM09062X103Stock353,233$142,685,000thousands by filing date
MYLAN NVN59465109SHS EURO1,837,005$124,659,000thousands by filing date
Vertex Pharmaceuticals Incorporated92532F100COM897,903$110,873,000thousands by filing date
ALEXION PHARMACEUTICALS INC015351109COM584,305$105,625,000thousands by filing date
ALLERGAN PLCG0177J108SHS343,686$104,295,000thousands by filing date
REGENERON PHARMACEUTICALS COM75886F107Stock187,166$95,479,000thousands by filing date
INCYTE CORP COM45337C102Stock880,461$91,753,000thousands by filing date
Johnson & Johnson478160104COM884,612$86,214,000thousands by filing date
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS881624209ADR1,387,594$82,007,000thousands by filing date
Amgen Inc.031162100COM497,280$76,342,000thousands by filing date
BIOMARIN PHARMACEUTICAL INC09061G101COM534,977$73,174,000thousands by filing date
ALKERMES PLCG01767105SHS1,035,470$66,622,000thousands by filing date
Pfizer Inc.717081103COM1,638,241$54,930,000thousands by filing date
ILLUMINA INC452327109COM229,641$50,144,000thousands by filing date
AETNA INC NEW00817Y108COM331,931$42,308,000thousands by filing date
AKORN INC009728106COM849,482$37,088,000thousands by filing date
Bristol-Myers Squibb Company110122108COM535,240$35,615,000thousands by filing date
CATAMARAN CORP148887102COM433,600$26,484,000thousands by filing date
ENDO INTL PLCG30401106SHS325,873$25,956,000thousands by filing date
MOLINA HEALTHCARE INC60855R100COM347,901$24,457,000thousands by filing date
VERADIGM INC01988P108COMMON STOCK1,778,200$24,326,000thousands by filing date
RECEPTOS, INC.756207106COMMON STOCK124,800$23,718,000thousands by filing date
ACORDA THERAPEUTICS INC00484M106COM680,862$22,693,000thousands by filing date
Amgen Inc.031162100COM146,000$22,414,000thousands by filing datecall
BAXTER INTL INC071813109COM319,600$22,350,000thousands by filing date
HUMANA INC COM444859102Stock112,000$21,423,000thousands by filing date
ISHARES TR464287556ISHARES BIOTECH57,670$21,278,000thousands by filing date
JAZZ PHARMACEUTICALS PLC SHS USDG50871105Stock120,357$21,191,000thousands by filing date
HCA Healthcare Inc40412C101COM213,788$19,395,000thousands by filing date
VENTAS INC COM92276F100REIT292,782$18,179,000thousands by filing date
NEUROCRINE BIOSCIENCES INC64125C109COM375,860$17,951,000thousands by filing date
PARATEK PHARMACEUTICALS INC699374302Equity691,000$17,807,000thousands by filing date
PHYSICIANS REALTY TRUST71943U104COM1,050,902$16,142,000thousands by filing date
IMPAX LABORATORIES INC45256B101COM344,683$15,828,000thousands by filing date
AMRN 3.5 1/32220480AB3Bond 30/360P2 U14,700,000$15,803,000thousands by filing dateprincipal
ALERE INC01449J105COM297,901$15,714,000thousands by filing date
ACADIA PHARMACEUTICALS INC004225108COM370,000$15,496,000thousands by filing date
MCKESSON CORP COM58155Q103Stock67,862$15,256,000thousands by filing date
MEDICAL PROPERTIES TRUST INC COM58463J304REIT1,153,574$15,123,000thousands by filing date
OMEGA HEALTHCARE INVS INC COM681936100REIT413,116$14,182,000thousands by filing date
HERON THERAPEUTICS INC427746102COM436,970$13,616,000thousands by filing date
COMMUNITY HEALTH SYSTEMS INC203668108COMMON STOCK209,572$13,197,000thousands by filing date
KARYOPHARM THERAPEUTICS INC48576U106COM476,966$12,978,000thousands by filing date
ALNYLAM PHARMACEUTICALS INC COM02043Q107Stock103,495$12,406,000thousands by filing date
ESPERION THERAPEUTICS INC NEW COM29664W105Stock148,000$12,100,000thousands by filing date
ESPERION THERAPEUTICS INC NEW COM29664W105Stock148,000$12,100,000thousands by filing datecall
CIGNA CORPORATION125509109COM74,251$12,029,000thousands by filing date
HEALTH CARE REIT INC CONV 6.5042217K601PFD200,000$11,888,000thousands by filing date
Stryker Corporation863667101COM123,940$11,845,000thousands by filing date
ST JUDE MED INC790849103COM161,510$11,802,000thousands by filing date
SABRA HEALTH CARE REIT INC COM78573L106REIT456,190$11,742,000thousands by filing date
MYLAN NVN59465109SHS EURO172,400$11,699,000thousands by filing datecall
THERAPEUTICSMD INC88338N107COM1,481,500$11,645,000thousands by filing date
Thermo Fisher Scientific Inc.883556102COM86,395$11,211,000thousands by filing date
ZIMMER BIOMET HOLDINGS INC COM98956P102Stock102,300$11,174,000thousands by filing date
PIERIS PHARMACEUTICALS INC720795103COM3,848,191$10,583,000thousands by filing date
Merck & Co.,Inc.58933Y105COM185,000$10,532,000thousands by filing date
AURIS MED HLDG AGH03579101COM2,105,263$10,400,000thousands by filing date
SAGENT PHARMACEUTICALS INC786692103COM409,500$9,955,000thousands by filing date
LTC PPTYS INC COM502175102REIT236,618$9,843,000thousands by filing date
CENTENE CORP DEL COM15135B101Stock120,000$9,648,000thousands by filing date
TENET HEALTHCARE CORP COM NEW88033G407Stock164,500$9,521,000thousands by filing date
VERASTEM INC92337C104COM1,249,827$9,424,000thousands by filing date
IRONWOOD PHARMACEUTICALS INC46333X108COMMON STOCK768,050$9,263,000thousands by filing date
Alliqua BioMedical Inc019621200COM NEW1,650,000$8,696,000thousands by filing date
IDEXX LABS INC COM45168D104Stock132,352$8,489,000thousands by filing date
ENDOLOGIX INC29266S106COM551,000$8,452,000thousands by filing date
SENIOR HSG PPTYS TR81721M109SH BEN INT479,604$8,417,000thousands by filing date
WELLCARE HEALTH PLANS INC94946T106COM88,652$7,520,000thousands by filing date
INTRA-CELLULAR THERAPIES INC46116X101COMMON STOCK227,164$7,258,000thousands by filing date
MERRIMACK PHARMACEUTICALS IN590328100COM567,787$7,021,000thousands by filing date
BLUEBIRD BIO INC09609G100COM40,895$6,885,000thousands by filing date
SUPERNUS PHARMACEUTICALS INC868459AB4NOTE 7.500% 5/02,000,000$6,655,000thousands by filing dateprincipal
ZOGENIX INC98978L105COM3,800,811$6,385,000thousands by filing date
ULTRAGENYX PHARMACEUTICAL IN90400D108COM60,000$6,143,000thousands by filing date
MEDIVATION INC58501N101COM53,700$6,133,000thousands by filing date
MEDIVATION INC58501N101COM53,700$6,133,000thousands by filing datecall
TENET HEALTHCARE CORP COM NEW88033G407Stock105,000$6,077,000thousands by filing datecall
HCA Healthcare Inc40412C101COM66,300$6,015,000thousands by filing datecall
ENDO INTL PLCG30401106SHS74,100$5,902,000thousands by filing datecall
ISIS PHARMACEUTICALS INC464330109COM98,200$5,651,000thousands by filing date
ISIS PHARMACEUTICALS INC464330109COM98,200$5,651,000thousands by filing datecall
ALLERGAN PLCG0177J116PFD CONV SER A5,000$5,213,000thousands by filing date
ACHILLION PHARMACEUTICALS IN00448Q201COM547,300$4,849,000thousands by filing date
EPIZYME INC29428V104COM200,000$4,800,000thousands by filing date
SPECTRUM PHARMACEUTICALS INC84763AAB4NOTE 2.750%12/15,000,000$4,694,000thousands by filing dateprincipal
FOAMIX PHARMACEUTICALS LTDM46135105SHS413,800$4,241,000thousands by filing date
KYTHERA BIOPHARMACEUTICALS I501570105COM55,717$4,196,000thousands by filing date
WRIGHT MED GROUP INC98235T107COM156,100$4,099,000thousands by filing date
FLEX PHARMA INC33938A105COM232,600$4,001,000thousands by filing date
AEGERION PHARMACEUTICALS INC00767E102COM206,000$3,908,000thousands by filing date
Accelerate Diagnostics00430H102COM144,625$3,733,000thousands by filing date
MERRIMACK PHARMACEUTICALS IN590328AA8NOTE 4.500% 7/11,485,000$3,113,000thousands by filing dateprincipal
TLOG 8 06/15/1988165UAB5Bond 30/360P2 U4,500,000$2,658,000thousands by filing dateprincipal
MYRIAD GENETICS INC62855J104COM74,800$2,542,000thousands by filing date
BIODELIVERY SCIENCES INTL IN09060J106COM250,000$1,990,000thousands by filing date
GENMARK DIAGNOSTICS INC372309104COM215,149$1,949,000thousands by filing date
DERMIRA INC24983L104COM97,197$1,706,000thousands by filing date
CELLECTIS ADS15117K103COM40,000$1,443,000thousands by filing date
TRILLIUM THERAPEUTICS INC COM NEW89620X506Stock65,000$1,418,000thousands by filing date
BELLICUM PHARMACEUTICALS INC079481107COM60,000$1,276,000thousands by filing date
ABAXIS INC002567105COM22,466$1,157,000thousands by filing date
SAGE THERAPEUTICS INC78667J108COM15,000$1,095,000thousands by filing date
INTELLIPHARMACEUTICS INTERNA458173101CMN354,047$1,041,000thousands by filing date
LAKEFRONT BIOTHERAPEUTICS NV36315X101SPON ADR20,000$1,030,000thousands by filing date
SANGAMO THERAPEUTICS INC800677106COM75,000$832,000thousands by filing date
CIDARA THERAPEUTICS INC COM NEW171757107Stock50,000$701,000thousands by filing date
ADAPTIMMUNE THERAPEUTICS PLC00653A107SPONDS ADR27,500$504,000thousands by filing date
MACROGENICS INC556099109COM12,743$484,000thousands by filing date
ZAFGEN INC98885E103COM13,307$461,000thousands by filing date
XENCOR INC98401F105COMMON STOCK20,000$439,000thousands by filing date
KITE PHARMA INC49803L109COM6,300$384,000thousands by filing date
ONCOGENEX PHARMACEUTICALS IN68230A106COM113,100$264,000thousands by filing date
AbbVie,Inc.00287Y109COM156$10,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001104659-15-058926this filing2015-08-12acceptance time not in the bulk data set