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13F-HR filed by Tekla Capital Management LLC

Tekla Capital Management LLC filed this 13F-HR for the quarter ended 2015-03-31, filed 2015-05-06, with 116 holding rows worth $2,523,695,000.

Accession
0001104659-15-034890
Filed
2015-05-06
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q1 2015

A holdings report, 116 entries on the cover page, a total value of $2,523,695,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $2,523,695,000 with VALUE read as thousands by filing date, 13F file number 028-10950. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
CELGENE CORP151020104COM1,994,834$229,964,000thousands by filing date
Gilead Sciences,Inc.375558103COM2,279,731$223,710,000thousands by filing date
BIOGEN INC COM09062X103Stock339,483$143,343,000thousands by filing date
ACTAVIS PLCG0083B108SHS361,686$107,645,000thousands by filing date
ALEXION PHARMACEUTICALS INC015351109COM502,305$87,049,000thousands by filing date
INCYTE CORP COM45337C102Stock936,461$85,836,000thousands by filing date
REGENERON PHARMACEUTICALS COM75886F107Stock187,166$84,502,000thousands by filing date
BIOMARIN PHARMACEUTICAL INC09061G101COM534,977$66,669,000thousands by filing date
AbbVie,Inc.00287Y109COM1,110,614$65,015,000thousands by filing date
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS881624209ADR997,594$62,150,000thousands by filing date
MYLAN NVN59465109SHS EURO1,010,105$59,950,000thousands by filing date
Pfizer Inc.717081103COM1,638,241$56,994,000thousands by filing date
Amgen Inc.031162100COM351,779$56,232,000thousands by filing date
Vertex Pharmaceuticals Incorporated92532F100COM464,244$54,767,000thousands by filing date
Johnson & Johnson478160104COM434,612$43,722,000thousands by filing date
Gilead Sciences,Inc.375558103COM430,100$42,206,000thousands by filing datecall
AKORN INC009728106COM849,482$40,359,000thousands by filing date
ALKERMES PLCG01767105SHS588,470$35,879,000thousands by filing date
AETNA INC NEW00817Y108COM331,931$35,361,000thousands by filing date
Bristol-Myers Squibb Company110122108COM535,240$34,523,000thousands by filing date
CATAMARAN CORP148887102COM433,600$25,817,000thousands by filing date
ILLUMINA INC452327109COM133,241$24,735,000thousands by filing date
MOLINA HEALTHCARE INC60855R100COM347,901$23,410,000thousands by filing date
ACORDA THERAPEUTICS INC00484M106COM680,862$22,659,000thousands by filing date
ENDO INTL PLCG30401106SHS251,773$22,584,000thousands by filing date
BAXTER INTL INC071813109COM319,600$21,893,000thousands by filing date
PERRIGO CO PLC SHSG97822103Stock130,652$21,629,000thousands by filing date
VENTAS INC COM92276F100REIT292,782$21,379,000thousands by filing date
VERADIGM INC01988P108COMMON STOCK1,778,200$21,267,000thousands by filing date
JAZZ PHARMACEUTICALS PLC SHS USDG50871105Stock120,741$20,863,000thousands by filing date
RECEPTOS, INC.756207106COMMON STOCK124,800$20,578,000thousands by filing date
NEUROCRINE BIOSCIENCES INC64125C109COM501,150$19,901,000thousands by filing date
ISHARES TR464287556ISHARES BIOTECH57,670$19,806,000thousands by filing date
SYNAGEVA BIOPHARMA CORP87159A103COM198,689$19,378,000thousands by filing date
Thermo Fisher Scientific Inc.883556102COM141,695$19,035,000thousands by filing date
PHYSICIANS REALTY TRUST71943U104COM1,050,902$18,506,000thousands by filing date
MEDICAL PROPERTIES TRUST INC COM58463J304REIT1,153,574$17,004,000thousands by filing date
OMEGA HEALTHCARE INVS INC COM681936100REIT413,116$16,760,000thousands by filing date
IMPAX LABORATORIES INC45256B101COM344,683$16,155,000thousands by filing date
AMRN 3.5 1/32220480AB3Bond 30/360P2 U14,700,000$15,656,000thousands by filing dateprincipal
MCKESSON CORP COM58155Q103Stock67,862$15,350,000thousands by filing date
SABRA HEALTH CARE REIT INC COM78573L106REIT456,190$15,123,000thousands by filing date
KARYOPHARM THERAPEUTICS INC48576U106COM476,966$14,600,000thousands by filing date
ALERE INC01449J105COM297,901$14,567,000thousands by filing date
ALNYLAM PHARMACEUTICALS INC COM02043Q107Stock130,195$13,595,000thousands by filing date
HEALTH CARE REIT INC CONV 6.5042217K601PFD200,000$13,432,000thousands by filing date
ALEXION PHARMACEUTICALS INC015351109COM77,200$13,379,000thousands by filing datecall
HERON THERAPEUTICS INC427746102COM873,940$12,716,000thousands by filing date
VERASTEM INC92337C104COM1,249,827$12,711,000thousands by filing date
IRONWOOD PHARMACEUTICALS INC46333X108COMMON STOCK768,050$12,289,000thousands by filing date
ZIMMER BIOMET HOLDINGS INC COM98956P102Stock102,300$12,022,000thousands by filing date
AbbVie,Inc.00287Y109COM200,000$11,708,000thousands by filing datecall
Stryker Corporation863667101COM123,940$11,433,000thousands by filing date
PERRIGO CO PLC SHSG97822103Stock67,700$11,208,000thousands by filing datecall
HCA Healthcare Inc40412C101COM147,488$11,096,000thousands by filing date
COMMUNITY HEALTH SYSTEMS INC203668108COMMON STOCK209,572$10,956,000thousands by filing date
LTC PPTYS INC COM502175102REIT236,618$10,884,000thousands by filing date
SANGAMO THERAPEUTICS INC800677106COM679,100$10,648,000thousands by filing date
SENIOR HSG PPTYS TR81721M109SH BEN INT479,604$10,642,000thousands by filing date
Merck & Co.,Inc.58933Y105COM185,000$10,634,000thousands by filing date
ST JUDE MED INC790849103COM161,510$10,563,000thousands by filing date
CIGNA CORPORATION125509109COM74,251$9,611,000thousands by filing date
SAGENT PHARMACEUTICALS INC786692103COM409,500$9,521,000thousands by filing date
AGIOS PHARMACEUTICALS INC00847X104COM100,300$9,458,000thousands by filing date
ENDOLOGIX INC29266S106COM551,000$9,406,000thousands by filing date
THERAPEUTICSMD INC88338N107COM1,481,500$8,963,000thousands by filing date
IDEXX LABS INC COM45168D104Stock56,265$8,692,000thousands by filing date
CENTENE CORP DEL COM15135B101Stock120,000$8,483,000thousands by filing date
WELLCARE HEALTH PLANS INC94946T106COM88,652$8,108,000thousands by filing date
SYNAGEVA BIOPHARMA CORP87159A103COM71,000$6,925,000thousands by filing datecall
ACCURAY INC DEL004397105COM731,943$6,807,000thousands by filing date
MERRIMACK PHARMACEUTICALS IN590328100COM567,787$6,745,000thousands by filing date
BLUEBIRD BIO INC09609G100COM54,527$6,585,000thousands by filing date
INFINITY PHARMACEUTICALS INC45665G303COM438,623$6,132,000thousands by filing date
ALNYLAM PHARMACEUTICALS INC COM02043Q107Stock54,300$5,670,000thousands by filing datecall
ILLUMINA INC452327109COM29,400$5,458,000thousands by filing datecall
ACHILLION PHARMACEUTICALS IN00448Q201COM547,300$5,396,000thousands by filing date
ACHILLION PHARMACEUTICALS IN00448Q201COM547,300$5,396,000thousands by filing datecall
AEGERION PHARMACEUTICALS INC00767E102COM206,000$5,391,000thousands by filing date
MOMENTA PHARMACEUTICALS INC60877T100COM353,575$5,374,000thousands by filing date
BIOGEN INC COM09062X103Stock12,200$5,151,000thousands by filing datecall
INCYTE CORP COM45337C102Stock56,000$5,133,000thousands by filing datecall
ACTAVIS PLCG0083B116PFD CONV SER A5,000$5,060,000thousands by filing date
SUPERNUS PHARMACEUTICALS INC868459AB4NOTE 7.500% 5/02,000,000$4,826,000thousands by filing dateprincipal
SPECTRUM PHARMACEUTICALS INC84763AAB4NOTE 2.750%12/15,000,000$4,572,000thousands by filing dateprincipal
FLEX PHARMA INC33938A105COM232,600$4,559,000thousands by filing date
TROVAGENE INC897238309COM650,000$4,427,000thousands by filing date
WRIGHT MED GROUP INC98235T107COM156,100$4,027,000thousands by filing date
ZOGENIX INC98978L105COM2,850,811$3,906,000thousands by filing date
INTELLIPHARMACEUTICS INTERNA458173101CMN1,394,000$3,889,000thousands by filing date
EPIZYME INC29428V104COM200,000$3,756,000thousands by filing date
INTRA-CELLULAR THERAPIES INC46116X101COMMON STOCK150,000$3,582,000thousands by filing date
Accelerate Diagnostics00430H102COM144,625$3,254,000thousands by filing date
SAREPTA THERAPEUTICS INC803607100COM230,300$3,058,000thousands by filing date
TENET HEALTHCARE CORP COM NEW88033G407Stock59,500$2,946,000thousands by filing date
MERRIMACK PHARMACEUTICALS IN590328AA8NOTE 4.500% 7/11,485,000$2,929,000thousands by filing dateprincipal
KYTHERA BIOPHARMACEUTICALS I501570105COM55,717$2,794,000thousands by filing date
ATHENAHEALTH INC04685W103COMMON STOCK23,100$2,758,000thousands by filing date
ATHENAHEALTH INC04685W103COMMON STOCK23,100$2,758,000thousands by filing datecall
KITE PHARMA INC49803L109COM46,500$2,682,000thousands by filing date
KITE PHARMA INC49803L109COM46,500$2,682,000thousands by filing datecall
MYRIAD GENETICS INC62855J104COM74,800$2,648,000thousands by filing date
MYRIAD GENETICS INC62855J104COM74,800$2,648,000thousands by filing datecall
BIODELIVERY SCIENCES INTL IN09060J106COM250,000$2,625,000thousands by filing date
COMMUNITY HEALTH SYSTEMS INC203668108COMMON STOCK50,000$2,614,000thousands by filing datecall
IMMUNOMEDICS INC452907108COM500,000$1,915,000thousands by filing date
SESEN BIO, INC.286221106COM195,964$1,748,000thousands by filing date
SORRENTO THERAPEUTICS INC83587F202COMMON STOCK142,597$1,648,000thousands by filing date
SAREPTA THERAPEUTICS INC803607100COM115,100$1,529,000thousands by filing datecall
BELLICUM PHARMACEUTICALS INC079481107COM60,000$1,390,000thousands by filing date
CELLECTIS ADS15117K103COM40,000$1,384,000thousands by filing date
SAGE THERAPEUTICS INC78667J108COM15,000$753,000thousands by filing date
ZAFGEN INC98885E103COM13,307$527,000thousands by filing date
MACROGENICS INC556099109COM12,743$400,000thousands by filing date
XENCOR INC98401F105COMMON STOCK20,000$306,000thousands by filing date
ONCOGENEX PHARMACEUTICALS IN68230A106COM113,100$243,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001104659-15-034890this filing2015-05-06acceptance time not in the bulk data set