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13F-HR filed by Artal Group S.A.

Artal Group S.A. filed this 13F-HR for the quarter ended 2021-12-31, filed 2022-02-11, with 150 holding rows worth $3,685,363,000.

Accession
0001053906-22-000002
Filed
2022-02-11
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q4 2021

A holdings report, 152 entries on the cover page, a total value of $3,685,363,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $3,685,363,000 with VALUE read as thousands by filing date, 13F file number 028-15027. The quarter's positions are built on this report. The resolved quarter.

Other managers

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
LEXICON PHARMACEUTICALS INC528872302COMMON STOCK71,178,364$280,443,000thousands by filing date
WW INTL INC98262P101COM14,818,300$239,019,000thousands by filing date
MIRATI THERAPEUTICS INC60468T105COM1,400,000$205,366,000thousands by filing date
BEONE MEDICINES LTD SPONSORED ADS07725L102ADR675,000$182,878,000thousands by filing date
ARGENX SE SPONSORED ADR04016X101ADR500,000$175,095,000thousands by filing date
SPDR SER TR78464A870S&P BIOTECH1,000,000$111,960,000thousands by filing datecall
ALNYLAM PHARMACEUTICALS INC COM02043Q107Stock650,000$110,227,000thousands by filing date
SEER INC81578P106COM CL A4,750,000$108,348,000thousands by filing date
FATE THERAPEUTICS INC31189P102COM1,800,000$105,318,000thousands by filing date
SEAGEN INC81181C104COM500,000$77,300,000thousands by filing date
MORPHIC HLDG INC61775R105COM1,585,049$75,100,000thousands by filing date
AMICUS THERAPEUTICS INC03152W109COM6,000,000$69,300,000thousands by filing date
BELLUS HEALTH INC NEW07987C204COM8,500,000$68,425,000thousands by filing date
KYMERA THERAPEUTICS INC501575104COM1,000,000$63,490,000thousands by filing date
Bristol-Myers Squibb Company110122108COM1,000,000$62,350,000thousands by filing datecall
SCHOLAR ROCK HLDG CORP80706P103COM2,450,000$60,858,000thousands by filing date
Citigroup Inc.172967424COM1,000,000$60,390,000thousands by filing datecall
SPRINGWORKS THERAPEUTICS INC85205L107COM850,000$52,683,000thousands by filing date
ERASCA INC COM29479A108Stock3,172,221$49,423,000thousands by filing date
KRYSTAL BIOTECH INC COM501147102Stock700,000$48,965,000thousands by filing date
CEREVEL THERAPEUTICS HLDNG I15678U128COM1,500,000$48,630,000thousands by filing date
CYTOKINETICS INC23282W605COM NEW1,000,000$45,580,000thousands by filing date
IGM BIOSCIENCES INC449585108COM1,500,000$43,995,000thousands by filing date
PROTAGONIST THERAPEUTICS74366E102COM1,250,000$42,750,000thousands by filing date
SAGE THERAPEUTICS INC78667J108COM1,000,000$42,540,000thousands by filing date
NOVABRIDGE BIOSCIENCES44975P103CMN850,000$40,282,000thousands by filing date
FOGHORN THERAPEUTICS INC344174107COMMON STOCK1,720,720$39,353,000thousands by filing date
RUBIUS THERAPEUTICS INC78116T103COM3,701,580$35,831,000thousands by filing date
INTELLIA THERAPEUTICS INC45826J105COM275,000$32,516,000thousands by filing date
TALARIS THERAPEUTICS INC87410C104COM2,064,262$31,563,000thousands by filing date
ALLOVIR INC019818103COM2,323,371$30,064,000thousands by filing date
EVOTEC SE FSPONSORED ADR 1 ADR REPS 0.5 ORD SHS30050E105Equity1,149,425$27,299,000thousands by filing date
EQRX INC26886C107COM4,000,000$27,280,000thousands by filing date
DENALI THERAPEUTICS INC COM24823R105Stock600,000$26,760,000thousands by filing date
GOSSAMER BIO INC COM38341P102Stock2,358,968$26,680,000thousands by filing date
OMEGA THERAPEUTICS INC68217N105COMMON STOCK2,273,530$25,759,000thousands by filing date
ITEOS THERAPEUTICS INC46565G104COM544,047$25,331,000thousands by filing date
REPLIMUNE GROUP INC76029N106COMMON STOCK900,000$24,390,000thousands by filing date
SCHRODINGER INC COM80810D103Stock700,000$24,381,000thousands by filing date
PRAXIS PRECISION MEDICINES I74006W108COM1,200,000$23,640,000thousands by filing date
ATARA BIOTHERAPEUTICS INC COM NEW046513107Stock1,500,000$23,640,000thousands by filing date
RELAY THERAPEUTICS INC COM75943R102Stock750,000$23,033,000thousands by filing date
AURINIA PHARMACEUTICALS INC COM05156V102Stock1,000,000$22,870,000thousands by filing date
Vertex Pharmaceuticals Incorporated92532F100COM100,000$21,960,000thousands by filing datecall
KRONOS BIO INC50107A104COM1,542,954$20,969,000thousands by filing date
AGENUS INC00847G705COM NEW6,500,000$20,930,000thousands by filing date
GENERATION BIO CO37148K100COM2,814,191$19,924,000thousands by filing date
AMBRX BIOPHARMA, INC. SPONSORED ADR02290A102COM2,152,291$19,435,000thousands by filing date
IKENA ONCOLOGY INC45175G108COM1,549,513$19,431,000thousands by filing date
NOVAGOLD RESOURCES INC66987E206COM NEW2,600,000$17,836,000thousands by filing date
APTINYX INC03836N103COM6,116,493$16,331,000thousands by filing date
Intel Corp458140100COM300,000$15,450,000thousands by filing datecall
TG THERAPEUTICS INC COM88322Q108Stock800,000$15,200,000thousands by filing date
REPARE THERAPEUTICS INC760273102COM700,000$14,763,000thousands by filing date
VERVE THERAPEUTICS INC92539P101COM400,000$14,748,000thousands by filing date
KURA ONCOLOGY INC COM50127T109Stock1,050,000$14,700,000thousands by filing date
SQZ BIOTECHNOLOGIES CO78472W104COM1,606,309$14,344,000thousands by filing date
FORMA THERAPEUTICS HLDGS INC34633R104SHS1,000,000$14,220,000thousands by filing date
ALBIREO PHARMA INC01345P106COMMON STOCK600,000$13,974,000thousands by filing date
SELECTA BIOSCIENCES INC816212104COM4,000,000$13,040,000thousands by filing date
LEAP THERAPEUTICS INC52187K101COM4,000,000$12,960,000thousands by filing date
TAYSHA GENE THERAPIES INC877619106COMMON STOCK1,040,882$12,126,000thousands by filing date
OATLY GROUP AB67421J108SPONSORED ADS1,500,000$11,940,000thousands by filing date
TURNING PT THERAPEUTICS90041T108COM250,000$11,925,000thousands by filing date
MARINUS PHARMACEUTICALS INC56854Q200COM NEW1,000,000$11,880,000thousands by filing date
ACHILLES THERAPEUTICS PL-ADR00449L102COM2,255,375$11,299,000thousands by filing date
EXSCIENTIA PLC30223G102ADS550,000$10,868,000thousands by filing date
ALX ONCOLOGY HOLDINGS INC00166B105COMMON STOCK500,000$10,745,000thousands by filing date
SAGE THERAPEUTICS INC78667J108COM250,000$10,635,000thousands by filing datecall
SYROS PHARMACEUTICALS INC87184Q107COM3,000,000$9,780,000thousands by filing date
GRITSTONE BIO INC39868T105COM750,000$9,645,000thousands by filing date
BLACK DIAMOND THERAPEUTICS I09203E105COM1,646,517$8,776,000thousands by filing date
GRAPHITE BIO INC38870X104COM700,000$8,701,000thousands by filing date
DESIGN THERAPEUTICS INC25056L103COM400,000$8,564,000thousands by filing date
ALPINE IMMUNE SCIENCES INC02083G100COM593,030$8,213,000thousands by filing date
NANOBIOTIX63009J107SPONSORED ADS1,000,000$8,100,000thousands by filing date
ADAGENE INC005329107CMN1,000,000$8,068,000thousands by filing date
OVID THERAPEUTICS INC690469101COMMON STOCK2,500,000$8,025,000thousands by filing date
SPERO THERAPEUTICS INC84833T103COM500,000$8,005,000thousands by filing date
Instil Bio, Inc.45783C101Common Stock450,000$7,700,000thousands by filing date
HARPOON THERAPEUTICS INC41358P106COM1,000,000$7,550,000thousands by filing date
Mersana Therapeutics Inc59045L106Common Stock1,200,000$7,464,000thousands by filing date
ZYMEWORKS INC98985W102COM450,000$7,376,000thousands by filing date
OMEGA ALPHA SPACG6749V107CL A750,000$7,328,000thousands by filing date
Xilio Therapeutics Inc.98422T100COM450,000$7,200,000thousands by filing date
IMMUNOCORE HLDGS PLC ADS45258D105ADR200,000$6,848,000thousands by filing date
IMMUNIC INC4525EP101COM700,000$6,699,000thousands by filing date
Y-mAbs Therapeutics Inc984241109Common Stock400,000$6,484,000thousands by filing date
VOR BIOPHARMA INC929033108COM550,000$6,391,000thousands by filing date
DYNE THERAPEUTICS INC COM26818M108Stock525,000$6,242,000thousands by filing date
SANA BIOTECHNOLOGY INC799566104COM400,000$6,192,000thousands by filing date
CURIS INC231269200COM1,300,000$6,188,000thousands by filing date
CARIBOU BIOSCIENCES INC COM142038108Stock405,347$6,117,000thousands by filing date
EVELO BIOSCIENCES INC299734103COM1,000,000$6,070,000thousands by filing date
STOKE THERAPEUTICS INC86150R107COM250,000$5,998,000thousands by filing date
AVIDITY BIOSCIENCES INC COM05370A108Stock250,000$5,943,000thousands by filing date
ORIC PHARMACEUTICALS INC68622P109COM400,000$5,880,000thousands by filing date
NEXIMMUNE INC65344D109COM1,200,000$5,532,000thousands by filing date
LYELL IMMUNOPHARMA INC55083R104COM700,000$5,418,000thousands by filing date
Adverum Biotechnologies, Inc.00773U108Common Stock3,000,000$5,280,000thousands by filing date
SOLID BIOSCIENCES INC COM NEW83422E105Stock3,000,000$5,250,000thousands by filing date
MIRION TECHNOLOGIES INC60471A101COM CL A500,000$5,235,000thousands by filing date
AEGLEA BIOTHERAPEUTICS INC00773J103COM1,045,000$4,964,000thousands by filing date
AC IMMUNE SAH00263105SHS1,000,000$4,950,000thousands by filing date
DYNAMICS SPECIAL PURPOSE COR268010105CLASS A COM500,000$4,930,000thousands by filing date
CYCLERION THERAPEUTICS INC23255M105COM2,779,122$4,780,000thousands by filing date
GDS HLDGS LTD SPONSORED ADS36165L108ADR100,000$4,716,000thousands by filing date
IQIYI INC SPONSORED ADS46267X108ADR1,000,000$4,560,000thousands by filing date
CARDIFF ONCOLOGY INC14147L108COM750,000$4,508,000thousands by filing date
23ANDME HOLDING CO90138Q108CLASS A COM661,009$4,402,000thousands by filing date
BRIDGEBIO PHARMA INC10806X102COM250,000$4,170,000thousands by filing date
CONTRAFECT CORP212326300COM1,500,000$3,945,000thousands by filing date
PHATHOM PHARMACEUTICALS INC71722W107COMMON STOCK200,000$3,934,000thousands by filing date
CULLINAN THERAPEUTICS INC230031106COM250,000$3,858,000thousands by filing date
PERCEPTION CAPITAL CORP IIIG7185D106CLASS A ORD SHS380,000$3,781,000thousands by filing date
Applied Therapeutics Inc03828A101Common Stock400,000$3,580,000thousands by filing date
TCR2 THERAPEUTICS INC87808K106COM750,000$3,495,000thousands by filing date
RECURSION PHARMACEUTICALS IN75629V104CL A200,000$3,426,000thousands by filing date
111 INC68247Q102ADR966,349$3,382,000thousands by filing date
IMMUTEP LTD45257L108SPONSORED ADS1,000,000$3,280,000thousands by filing date
WAVE LIFE SCIENCES LTD SHSY95308105Stock1,000,000$3,140,000thousands by filing date
FUSION PHARMACEUTICALS INC36118A100COM750,000$3,128,000thousands by filing date
CHINOOK THERAPEUTICS INC16961L106COM180,500$2,944,000thousands by filing date
Aravive Inc03890D108Common / Ordinary Stock1,311,291$2,872,000thousands by filing date
MEI PHARMA INC55279B202COM NEW1,000,000$2,670,000thousands by filing date
OLEMA PHARMACEUTICALS INC68062P106COM260,500$2,438,000thousands by filing date
MEREO BIOPHARMA GROUP PLC589492107CMN1,500,000$2,400,000thousands by filing date
ORCHARD THERAPEUTICS PLC68570P101ADR1,803,858$2,381,000thousands by filing date
CODIAK BIOSCIENCES INC192010106COM200,000$2,228,000thousands by filing date
KINNATE BIOPHARMA INC49705R105COM125,000$2,215,000thousands by filing date
Hippo Holdings, Inc. (HIPO)433539103Common Stocks600,000$1,698,000thousands by filing date
AMRYT PHARMA LTD - SPNR ADR03217L106COMMON EQUITY150,480$1,625,000thousands by filing date
AXCELLA HEALTH INC05454B105COM712,500$1,489,000thousands by filing date
HOOKIPA PHARMA INC43906K100COM599,616$1,397,000thousands by filing date
INKT603693102Stock289,588$1,292,000thousands by filing date
IRONWOOD PHARMACEUTICALS INC46333X108COMMON STOCK110,532$1,289,000thousands by filing date
CORVUS PHARMACEUTICALS INC221015100COM500,000$1,205,000thousands by filing date
KALEIDO BIOSCIENCES INC483347100COM500,500$1,196,000thousands by filing date
LAVA THERAPEUTICS NVN51517105SHS200,000$1,100,000thousands by filing date
DECIPHERA PHARMACEUTICALS IN24344T101COM100,000$977,000thousands by filing date
RIGEL PHARMACEUTICALS INC766559603COMMON STOCK321,100$851,000thousands by filing date
SIGILON THERAPEUTICS INC82657L107COM276,000$762,000thousands by filing date
MARRONE BIO INNOVATIONS INC57165B106COM1,048,679$755,000thousands by filing date
RIVIAN AUTOMOTIVE INC COM CL A76954A103Stock7,000$726,000thousands by filing date
DLOCAL LTDG29018101CLASS A COM20,000$714,000thousands by filing date
YUMANITY THERAPEUTICS INC98872L102COM217,391$643,000thousands by filing date
METACRINE INC59101E103COM924,898$624,000thousands by filing date
SURFACE ONCOLOGY INC86877M209COM100,000$478,000thousands by filing date
CIDARA THERAPEUTICS INC COM NEW171757107Stock224,675$285,000thousands by filing date
ASTRIA THERAPEUTICS INC COM04635X102Stock33,333$180,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001053906-22-000002this filing2022-02-11acceptance time not in the bulk data set