13F-HR filed by PERCEPTIVE ADVISORS LLC
PERCEPTIVE ADVISORS LLC filed this 13F-HR for the quarter ended 2024-09-30, filed 2024-11-14, with 108 holding rows worth $4,726,735,830.
- Accession
- 0001012975-24-000488
- Filer
- CIK 1224962
- Filed
- 2024-11-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q3 2024
A holdings report, 108 entries on the cover page, a total value of $4,726,735,830 stated on the cover page (in dollars after the unit check, H1), rows summing to $4,726,735,830 with VALUE read as dollars as filed, 13F file number 028-10438. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| ARCELLX INC COMMON STOCK | 03940C100 | Stock | 3,888,669 | $324,742,748 | dollars as filed | |
| NUVALENT INC COM | 670703107 | Stock | 2,979,235 | $304,775,741 | dollars as filed | |
| AMICUS THERAPEUTICS INC | 03152W109 | COM | 28,057,456 | $299,653,630 | dollars as filed | |
| IOVANCE BIOTHERAPEUTICS INC | 462260100 | COM | 26,617,709 | $249,940,287 | dollars as filed | |
| VAXCYTE INC COM | 92243G108 | Stock | 2,027,608 | $231,694,766 | dollars as filed | |
| RHYTHM PHARMACEUTICALS INC | 76243J105 | COM | 3,560,214 | $186,519,611 | dollars as filed | |
| VERONA PHARMA PLC | 925050106 | SPONSORED ADS | 6,315,933 | $181,709,392 | dollars as filed | |
| SOLENO THERAPEUTICS INC | 834203309 | COM | 3,204,976 | $161,819,238 | dollars as filed | |
| INTRA-CELLULAR THERAPIES INC | 46116X101 | COMMON STOCK | 1,622,215 | $118,697,472 | dollars as filed | |
| APOGEE THERAPEUTICS INC COM | 03770N101 | Stock | 2,015,007 | $118,361,511 | dollars as filed | |
| VIKING THERAPEUTICS INC | 92686J106 | COM | 1,699,987 | $107,626,177 | dollars as filed | |
| CENTESSA PHARMACEUTICALS PLC | 152309100 | SPONSORED ADS | 6,282,290 | $100,453,817 | dollars as filed | |
| IMMATICS N.V | N44445109 | SHS | 8,086,159 | $92,263,074 | dollars as filed | |
| EVOLUS INC | 30052C107 | COM | 5,356,622 | $86,777,276 | dollars as filed | |
| SPYRE THERAPEUTICS INC | 00773J202 | COM NEW | 2,872,547 | $84,481,607 | dollars as filed | |
| ARTIVION INC | 228903100 | COM | 2,793,703 | $74,368,374 | dollars as filed | |
| BIOHAVEN LTD | G1110E107 | COM | 1,485,232 | $74,217,043 | dollars as filed | |
| ASTRIA THERAPEUTICS INC COM | 04635X102 | Stock | 6,485,420 | $71,404,474 | dollars as filed | |
| AXSOME THERAPEUTICS INC. COM | 05464T104 | Stock | 782,844 | $70,354,190 | dollars as filed | |
| Applied Therapeutics Inc | 03828A101 | Common Stock | 8,005,000 | $68,042,500 | dollars as filed | |
| CARGO THERAPEUTICS INC COM | 14179K101 | Stock | 3,683,004 | $67,951,423 | dollars as filed | |
| IMMUNOVANT INC | 45258J102 | COM | 2,378,762 | $67,818,505 | dollars as filed | |
| PRAXIS PRECISION MEDICINES I | 74006W207 | COM NEW | 1,164,035 | $66,978,574 | dollars as filed | |
| ARGENX SE SPONSORED ADR | 04016X101 | ADR | 118,839 | $64,420,245 | dollars as filed | |
| VIRIDIAN THERAPEUTICS INC | 92790C104 | COM | 2,812,665 | $63,988,129 | dollars as filed | |
| EDGEWISE THERAPEUTICS INC | 28036F105 | COM | 2,330,294 | $62,195,547 | dollars as filed | |
| PROTAGONIST THERAPEUTICS | 74366E102 | COM | 1,374,563 | $61,855,335 | dollars as filed | |
| MEIRAGTX HOLDINGS PLC | G59665102 | COMMON STOCK | 12,581,103 | $52,430,095 | dollars as filed | |
| ALDEYRA THERAPEUTICS INC | 01438T106 | COM | 9,275,851 | $49,996,837 | dollars as filed | |
| AKERO THERAPEUTICS INC | 00973Y108 | COM | 1,714,806 | $49,197,784 | dollars as filed | |
| SOLID BIOSCIENCES INC | 83422E204 | COMMON STOCK | 6,906,646 | $48,139,322 | dollars as filed | |
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 1,296,416 | $42,639,122 | dollars as filed | |
| SPDR SER TR | 78464A870 | S&P BIOTECH | 400,000 | $39,520,000 | dollars as filed | put |
| ACRIVON THERAPEUTICS INC | 004890109 | CMN | 5,360,858 | $37,526,006 | dollars as filed | |
| CRINETICS PHARMACEUTICALS INC COM | 22663K107 | Stock | 724,698 | $37,032,068 | dollars as filed | |
| NAUTILUS BIOTECHNOLOGY INC | 63909J108 | COM | 12,594,211 | $35,893,501 | dollars as filed | |
| CELCUITY INC | 15102K100 | COM | 2,362,279 | $35,221,580 | dollars as filed | |
| INSULET CORP COM | 45784P101 | Stock | 142,269 | $33,113,110 | dollars as filed | |
| ORUKA THERAPEUTICS INC COM | 687604108 | Stock | 1,235,187 | $30,274,433 | dollars as filed | |
| CONTINEUM THERAPEUTICS INC CL A | 21217B100 | Stock | 1,516,668 | $29,029,026 | dollars as filed | |
| OCULAR THERAPEUTIX INC | 67576A100 | COM | 3,324,468 | $28,922,872 | dollars as filed | |
| Intuitive Surgical,Inc. | 46120E602 | COM | 58,119 | $28,552,121 | dollars as filed | |
| NATERA INC COM | 632307104 | Stock | 220,000 | $27,929,000 | dollars as filed | |
| CG ONCOLOGY INC | 156944100 | COMMON STOCK | 733,695 | $27,682,312 | dollars as filed | |
| ZYMEWORKS INC | 98985Y108 | COM | 2,180,020 | $27,359,251 | dollars as filed | |
| DYNE THERAPEUTICS INC COM | 26818M108 | Stock | 718,144 | $25,795,732 | dollars as filed | |
| Adagio Med Hldgs Inc Com | 00534B100 | Common Stock | 9,812,419 | $25,316,041 | dollars as filed | |
| ARVINAS INC | 04335A105 | COM | 1,027,749 | $25,313,458 | dollars as filed | |
| PROCEPT BIOROBOTICS CORP COM | 74276L105 | Stock | 315,659 | $25,290,599 | dollars as filed | |
| NEUROCRINE BIOSCIENCES INC | 64125C109 | COM | 212,228 | $24,452,910 | dollars as filed | |
| ORCHESTRA BIOMED HOLDINGS IN | 68572M106 | COMMON STOCK | 4,592,556 | $23,605,738 | dollars as filed | |
| Instil Bio Inc | 45783C200 | COM NEW | 345,545 | $23,262,089 | dollars as filed | |
| LIVANOVA PLC | G5509L101 | SHS | 429,000 | $22,539,660 | dollars as filed | |
| SPRINGWORKS THERAPEUTICS INC | 85205L107 | COM | 692,263 | $22,180,107 | dollars as filed | |
| Medtronic Plc | G5960L103 | COM | 245,332 | $22,087,240 | dollars as filed | |
| ADMA BIOLOGICS INC | 000899104 | COM | 1,060,200 | $21,193,398 | dollars as filed | |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 524,930 | $20,666,494 | dollars as filed | |
| ZENAS BIOPHARMA INC COM | 98937L105 | Stock | 1,144,035 | $19,357,072 | dollars as filed | |
| DISC MEDICINE INC COM | 254604101 | Stock | 387,017 | $19,018,015 | dollars as filed | |
| ROCKET PHARMACEUTICALS INC | 77313F106 | COM | 931,851 | $17,211,288 | dollars as filed | |
| INHIBRX BIOSCIENCES INC | 45720N103 | COM | 1,064,026 | $16,662,647 | dollars as filed | |
| RAPPORT THERAPEUTICS INC COM | 75383L102 | Stock | 748,183 | $15,322,788 | dollars as filed | |
| MERUS N V | N5749R100 | COM | 300,000 | $14,988,000 | dollars as filed | |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 180,000 | $13,140,000 | dollars as filed | |
| ICON PUB LTD CO SHS | G4705A100 | Stock | 44,353 | $12,743,060 | dollars as filed | |
| ARCUTIS BIOTHERAPEUTICS INC | 03969K108 | COM | 1,358,500 | $12,634,050 | dollars as filed | |
| PEPGEN INC COM | 713317105 | Stock | 1,410,438 | $12,059,245 | dollars as filed | |
| TYRA BIOSCIENCES INC | 90240B106 | COMMON STOCK | 511,226 | $12,018,923 | dollars as filed | |
| XENCOR INC | 98401F105 | COMMON STOCK | 527,671 | $10,611,464 | dollars as filed | |
| VERRICA PHARMACEUTICALS INC | 92511W108 | COM | 7,099,182 | $10,293,814 | dollars as filed | |
| ROIVANT SCIENCES LTD | G76279101 | SHS | 847,745 | $9,782,977 | dollars as filed | |
| ARRIVENT BIOPHARMA INC | 04272N102 | COM | 415,000 | $9,752,500 | dollars as filed | |
| EXACT SCIENCES CORP COM | 30063P105 | Stock | 125,000 | $8,515,000 | dollars as filed | |
| EYEPOINT INC COM NEW | 30233G209 | Stock | 1,037,274 | $8,287,819 | dollars as filed | |
| ALLOGENE THERAPEUTICS INC | 019770106 | COM | 2,725,000 | $7,630,000 | dollars as filed | |
| VERONA PHARMA PLC | 925050106 | SPONSORED ADS | 250,000 | $7,192,500 | dollars as filed | put |
| VERONA PHARMA PLC | 925050106 | SPONSORED ADS | 250,000 | $7,192,500 | dollars as filed | call |
| AMYLYX PHARMACEUTICALS INC | 03237H101 | COM | 2,125,649 | $6,887,103 | dollars as filed | |
| BICYCLE THERAPEUTICS PLC-ADR | 088786108 | SPONSORED ADS | 255,994 | $5,793,144 | dollars as filed | |
| Veru Inc | 92536C103 | Common Stock | 7,283,157 | $5,600,748 | dollars as filed | |
| FILANA THERAPEUTICS INC | 14817C107 | CMN | 183,000 | $5,385,690 | dollars as filed | put |
| FULCRUM THERAPEUTICS INC | 359616109 | COMMON STOCK | 1,500,000 | $5,355,000 | dollars as filed | call |
| HELIX ACQUISITION CORP II | G4444H101 | CL A ORD SHS | 500,000 | $5,224,950 | dollars as filed | |
| BIODESIX INC | 09075X108 | COM | 2,173,880 | $3,869,506 | dollars as filed | |
| PRECISION BIOSCIENCES INC | 74019P207 | COM NEW | 426,293 | $3,819,585 | dollars as filed | |
| MEREO BIOPHARMA GROUP PLC | 589492107 | CMN | 815,722 | $3,352,617 | dollars as filed | |
| LYRA THERAPEUTICS INC | 55234L105 | COM | 12,757,562 | $3,278,693 | dollars as filed | |
| NANOBIOTIX | 63009J107 | SPONSORED ADS | 555,066 | $3,191,630 | dollars as filed | |
| ABSCI CORPORATION | 00091E109 | COM | 700,000 | $2,674,000 | dollars as filed | |
| ATHIRA PHARMA INC | 04746L104 | COM | 5,402,964 | $2,409,722 | dollars as filed | |
| X4 Pharmaceuticals, Inc. | 98420X103 | COM | 3,545,454 | $2,372,972 | dollars as filed | |
| ENVVENO MEDICAL CORPORATION | 29415J106 | COM | 694,315 | $2,332,898 | dollars as filed | |
| KYMERA THERAPEUTICS INC | 501575104 | COM | 46,213 | $2,187,261 | dollars as filed | |
| TRINITY BIOTECH INVT LTD | 896438504 | SPONS ADR NEW | 1,800,000 | $1,980,000 | dollars as filed | |
| PYXIS ONCOLOGY INC COMMON STOCK | 747324101 | Stock | 508,462 | $1,866,056 | dollars as filed | |
| IRHYTHM HOLDINGS INC COM | 450056106 | Stock | 22,591 | $1,677,156 | dollars as filed | |
| STRUCTURE THERAPEUTICS INC COMP | 86366E106 | EQUITY | 34,852 | $1,529,654 | dollars as filed | |
| LEXEO THERAPEUTICS INC | 52886X107 | COMMON STOCK | 139,835 | $1,264,108 | dollars as filed | |
| NOVAVAX INC | 670002401 | COM NEW | 100,000 | $1,263,000 | dollars as filed | put |
| FATE THERAPEUTICS INC | 31189P102 | COM | 345,575 | $1,209,513 | dollars as filed | |
| SINGULAR GENOMICS SYSTEMS IN | 82933R308 | COM | 50,896 | $797,540 | dollars as filed | |
| KYVERNA THERAPEUTICS INC | 501976104 | COMMON STOCK | 150,000 | $733,500 | dollars as filed | |
| FORTE BIOSCIENCES INC | 34962G208 | COMMON STOCK | 95,742 | $535,198 | dollars as filed | |
| SYROS PHARMACEUTICALS INC | 87184Q206 | COM NEW | 116,754 | $251,021 | dollars as filed | |
| CAREMAX INC | 14171W202 | COM | 100,000 | $170,000 | dollars as filed | |
| REVOLUTION MEDICINES INC | 76155X118 | *W EXP 12/17/202 | 250,000 | $35,000 | dollars as filed | |
| SURROZEN INC | 86889P117 | *W EXP 08/01/203 | 166,666 | $1,717 | dollars as filed | |
| CAREMAX INC | 14171W111 | *W EXP 06/08/202 | 60,000 | $594 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001012975-24-000488 | this filing | 2024-11-14 | acceptance time not in the bulk data set |