13F-HR filed by EcoR1 Capital, LLC
EcoR1 Capital, LLC filed this 13F-HR for the quarter ended 2022-12-31, filed 2023-02-14, with 66 holding rows worth $3,285,596,936.
- Accession
- 0000935836-23-000229
- Filer
- CIK 1587114
- Filed
- 2023-02-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2022
A holdings report, 66 entries on the cover page, a total value of $3,285,596,936 stated on the cover page (in dollars after the unit check, H1), rows summing to $3,285,596,936 with VALUE read as dollars as filed, 13F file number 028-16764. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| PROTHENA CORP PLC SHS | G72800108 | Stock | 11,584,280 | $697,952,870 | dollars as filed | |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 2,999,453 | $388,669,120 | dollars as filed | |
| APELLIS PHARMACEUTICALS INC | 03753U106 | COM | 5,183,431 | $268,035,217 | dollars as filed | |
| ANAPTYSBIO INC | 032724106 | COM | 7,521,024 | $233,076,534 | dollars as filed | |
| LAKEFRONT BIOTHERAPEUTICS NV | 36315X101 | SPON ADR | 3,730,730 | $165,569,797 | dollars as filed | |
| XENCOR INC | 98401F105 | COMMON STOCK | 5,282,516 | $137,556,717 | dollars as filed | |
| ARVINAS INC | 04335A105 | COM | 3,123,300 | $106,848,093 | dollars as filed | |
| REVOLUTION MEDICINES INC COM | 76155X100 | Stock | 4,458,731 | $106,206,972 | dollars as filed | |
| MORPHIC HLDG INC | 61775R105 | COM | 3,951,566 | $105,704,391 | dollars as filed | |
| ACADIA PHARMACEUTICALS INC | 004225108 | COM | 5,991,479 | $95,384,346 | dollars as filed | |
| SPRINGWORKS THERAPEUTICS INC | 85205L107 | COM | 3,460,208 | $90,000,010 | dollars as filed | |
| KURA ONCOLOGY INC COM | 50127T109 | Stock | 6,638,371 | $82,382,184 | dollars as filed | |
| ZAI LAB LTD ADR | 98887Q104 | ADR | 2,157,686 | $66,240,960 | dollars as filed | |
| RELAY THERAPEUTICS INC COM | 75943R102 | Stock | 4,163,824 | $62,207,531 | dollars as filed | |
| ZYMEWORKS INC | 98985Y108 | COM | 7,568,573 | $59,488,984 | dollars as filed | |
| ALECTOR INC | 014442107 | COMMON STOCK | 4,056,548 | $37,441,938 | dollars as filed | |
| NGM BIOPHARMACEUTICALS INC | 62921N105 | COM | 6,435,518 | $32,306,300 | dollars as filed | |
| ADICET BIO INC | 007002108 | COM | 3,560,700 | $31,832,658 | dollars as filed | |
| EDGEWISE THERAPEUTICS INC | 28036F105 | COM | 3,493,194 | $31,229,154 | dollars as filed | |
| TANGO THERAPEUTICS INC | 87583X109 | COM | 4,201,414 | $30,460,252 | dollars as filed | |
| ATEA PHARMACEUTICALS INC | 04683R106 | COMMON STOCK | 6,184,861 | $29,749,181 | dollars as filed | |
| VOYAGER THERAPEUTICS INC | 92915B106 | COMMON STOCK | 4,753,907 | $28,998,833 | dollars as filed | |
| ALLOGENE THERAPEUTICS INC | 019770106 | COM | 4,488,200 | $28,230,778 | dollars as filed | |
| DYNE THERAPEUTICS INC COM | 26818M108 | Stock | 2,322,384 | $26,916,431 | dollars as filed | |
| NUVATION BIO INC COM CL A | 67080N101 | Stock | 13,896,543 | $26,681,363 | dollars as filed | |
| CRINETICS PHARMACEUTICALS INC COM | 22663K107 | Stock | 1,330,263 | $24,343,813 | dollars as filed | |
| ORIC PHARMACEUTICALS INC | 68622P109 | COM | 3,418,068 | $20,132,421 | dollars as filed | |
| KYMERA THERAPEUTICS INC | 501575104 | COM | 796,093 | $19,870,481 | dollars as filed | |
| GRAPHITE BIO INC | 38870X104 | COM | 5,712,096 | $18,964,159 | dollars as filed | |
| JANUX THERAPEUTICS INC | 47103J105 | COM | 1,421,319 | $18,718,771 | dollars as filed | |
| CHINOOK THERAPEUTICS INC | 16961L106 | COM | 690,000 | $18,078,000 | dollars as filed | |
| CENTESSA PHARMACEUTICALS PLC | 152309100 | SPONSORED ADS | 5,232,279 | $16,220,065 | dollars as filed | |
| POSEIDA THERAPEUTICS INC | 73730P108 | COM | 2,650,000 | $14,045,000 | dollars as filed | |
| Ventyx Biosciences Inc | 92332V107 | Common Stock | 400,000 | $13,116,000 | dollars as filed | |
| OVID THERAPEUTICS INC | 690469101 | COMMON STOCK | 6,117,400 | $11,378,364 | dollars as filed | |
| PRIME MEDICINE INC | 74168J101 | COM | 600,000 | $11,148,000 | dollars as filed | |
| CULLINAN THERAPEUTICS INC | 230031106 | COM | 1,035,038 | $10,919,651 | dollars as filed | |
| 2SEVENTY BIO INC COMMON STOCK | 901384107 | Stock | 1,143,494 | $10,714,539 | dollars as filed | |
| GERON CORP | 374163103 | COM | 4,028,507 | $9,748,987 | dollars as filed | |
| AVEO PHARMACEUTICALS INC | 053588307 | COM | 650,489 | $9,724,811 | dollars as filed | |
| BIOATLA INC | 09077B104 | COM | 1,124,439 | $9,276,622 | dollars as filed | |
| DESIGN THERAPEUTICS INC | 25056L103 | COM | 884,903 | $9,079,105 | dollars as filed | |
| GRACELL BIOTECHNOLOGIES INC | 38406L103 | ADR | 3,343,202 | $7,689,365 | dollars as filed | |
| MACROGENICS INC | 556099109 | COM | 1,117,455 | $7,498,123 | dollars as filed | |
| IMMATICS N.V | N44445109 | SHS | 743,000 | $6,471,530 | dollars as filed | |
| ARCUTIS BIOTHERAPEUTICS INC | 03969K108 | COM | 415,322 | $6,146,766 | dollars as filed | |
| PRECISION BIOSCIENCES INC | 74019P108 | COM | 5,035,971 | $5,992,805 | dollars as filed | |
| HEALTH SCIENCES ACQ CORP 2 | G4411D109 | ORD SHS | 400,000 | $3,992,000 | dollars as filed | |
| SELECTA BIOSCIENCES INC | 816212104 | COM | 3,500,000 | $3,955,000 | dollars as filed | |
| PRAXIS PRECISION MEDICINES I | 74006W108 | COM | 1,585,324 | $3,773,071 | dollars as filed | |
| ALIGOS THERAPEUTICS INC COM NEW | 01626L105 | Stock | 3,948,360 | $3,762,392 | dollars as filed | |
| ABEONA THERAPEUTICS INC | 00289Y206 | COM NEW | 1,086,956 | $3,347,824 | dollars as filed | |
| SURFACE ONCOLOGY INC | 86877M209 | COM | 3,924,713 | $3,218,265 | dollars as filed | |
| ERASCA INC COM | 29479A108 | Stock | 678,441 | $2,924,081 | dollars as filed | |
| HOOKIPA PHARMA INC | 43906K100 | COM | 2,473,489 | $2,003,526 | dollars as filed | |
| EUCRATES BIOMEDICAL ACQU COR | G3141W106 | CMN | 200,000 | $1,998,000 | dollars as filed | |
| NUVATION BIO INC | 67080N119 | WARR | 963,333 | $1,849,599 | dollars as filed | |
| ARYA SCIENCES ACQU CORP IV | G31659108 | COM | 150,000 | $1,515,000 | dollars as filed | |
| Tempest Therapeutics, Inc. | 87978U108 | Common Stock | 1,031,268 | $1,185,958 | dollars as filed | |
| ITEOS THERAPEUTICS INC | 46565G104 | COM | 40,480 | $790,574 | dollars as filed | |
| NEWAMSTERDAM PHARMA CO NV-27 | N62509117 | WTS | 66,665 | $726,649 | dollars as filed | |
| EUCRATES BIOMEDICAL ACQU COR | G3141W122 | *W EXP 10/23/202 | 66,666 | $665,993 | dollars as filed | |
| KRONOS BIO INC | 50107A104 | COM | 326,780 | $529,384 | dollars as filed | |
| BLACK DIAMOND THERAPEUTICS I | 09203E105 | COM | 282,131 | $507,836 | dollars as filed | |
| CAREMAX INC | 14171W111 | *W EXP 06/08/202 | 100,000 | $365,000 | dollars as filed | |
| SURROZEN INC | 86889P117 | *W EXP 08/01/203 | 66,665 | $38,792 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0000935836-23-000229 | this filing | 2023-02-14 | acceptance time not in the bulk data set |