13F-HR filed by TWO SIGMA ADVISERS, LP
TWO SIGMA ADVISERS, LP filed this 13F-HR for the quarter ended 2022-06-30, filed 2022-08-15, with 2,619 holding rows worth $35,251,448,000.
- Accession
- 0000919574-22-005031
- Filer
- CIK 1478735
- Filed
- 2022-08-15
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q2 2022
A holdings report, 2,619 entries on the cover page, a total value of $35,251,448,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $35,251,448,000 with VALUE read as thousands by filing date, 13F file number 028-14367. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerTWO SIGMA ABSOLUTE RETURN PORTFOLIO, LLC028-15367
- included managerTWO SIGMA ACTIVE EXTENSION U.S. ALL CAP EQUITY PORTFOLIO, LLC028-15404
- included managerTwo Sigma Active Extension U.S. Small Cap Equity Fund, LP028-15364
- included managerTwo Sigma Macro Portfolio, LLC028-16751
- included managerTwo Sigma World Core Fund, LP028-17350
- included managerTwo Sigma Equity Risk Premia Portfolio, LLC028-17346
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| CONTRAFECT CORP | 212326300 | COM | 13,100 | $40,000 | thousands by filing date | |
| IRIDEX CORP | 462684101 | COM | 15,100 | $39,000 | thousands by filing date | |
| FORESIGHT AUTONOMOUS HLDGS L | 345523104 | SPONSORED ADS | 62,300 | $39,000 | thousands by filing date | |
| VINCERX PHARMA INC | 92731L106 | COM NEW | 29,500 | $39,000 | thousands by filing date | |
| INVIVYD INC | 00534A102 | COMMON STOCK | 11,600 | $38,000 | thousands by filing date | |
| SPECTRUM PHARMACEUTICALS INC | 84763A108 | COM | 48,300 | $38,000 | thousands by filing date | |
| CALADRIUS BIOSCIENCES INC | 128058203 | COM NEW | 68,800 | $36,000 | thousands by filing date | |
| ARTS WAY MFG INC | 043168103 | COM | 11,800 | $35,000 | thousands by filing date | |
| WINDTREE THERAPEUTICS INC | 97382D303 | COM | 84,700 | $35,000 | thousands by filing date | |
| STAR EQUITY HOLDINGS INC | 85513Q103 | COMMON | 37,500 | $35,000 | thousands by filing date | |
| GLOBAL CORD BLOOD CORP | G39342103 | COM | 11,400 | $34,000 | thousands by filing date | |
| APPLIED GENETIC TECHNOL CORP | 03820J100 | COM | 44,049 | $34,000 | thousands by filing date | |
| COGNITION THERAPEUTICS INC | 19243B102 | COM | 15,600 | $33,000 | thousands by filing date | |
| AURORA MOBILE LTD | 051857100 | ADS | 30,700 | $33,000 | thousands by filing date | |
| SmileDirectClub Inc | 83192H106 | COM | 31,200 | $32,000 | thousands by filing date | |
| AQUESTIVE THERAPEUTICS INC COM | 03843E104 | Stock | 47,900 | $31,000 | thousands by filing date | |
| VISLINK TECHNOLOGIES INC | 92836Y300 | COM | 52,400 | $31,000 | thousands by filing date | |
| AVALON HLDGS CORP | 05343P109 | CL A | 11,700 | $30,000 | thousands by filing date | |
| SO YOUNG INTERNATIONAL INC | 83356Q108 | SPONSORED ADS | 34,600 | $30,000 | thousands by filing date | |
| GT BIOPHARMA INC | 36254L209 | COM NEW | 10,200 | $30,000 | thousands by filing date | |
| LIVEONE INC | 53814X102 | COM | 34,700 | $30,000 | thousands by filing date | |
| BIOFRONTERA INC | 09077D100 | COM | 16,200 | $30,000 | thousands by filing date | |
| ARDELYX INC | 039697107 | COM | 48,900 | $29,000 | thousands by filing date | |
| SALEM MEDIA GROUP INC CLASS A | 794093104 | COM | 13,600 | $29,000 | thousands by filing date | |
| EYENOVIA INC | 30234E104 | COM | 14,700 | $29,000 | thousands by filing date | |
| THERIVA BIOLOGICS INC COM NEW | 87164U201 | Stock | 135,300 | $29,000 | thousands by filing date | |
| CURIOSITYSTREAM INC | 23130Q107 | COMMON STOCK | 16,700 | $28,000 | thousands by filing date | |
| ATI PHYSICAL THERAPY INC | 00216W109 | COM CL A | 19,700 | $28,000 | thousands by filing date | |
| PLUS THERAPEUTICS INC | 72941H400 | COM | 49,400 | $27,000 | thousands by filing date | |
| HYRECAR INC | 44916T107 | COM | 44,700 | $27,000 | thousands by filing date | |
| CAPSTONE GREEN ENERGY CORP. | 14067D508 | Common Stock | 10,803 | $27,000 | thousands by filing date | |
| AMERICAN SHARED HOSPITAL SVC | 029595105 | COM | 11,800 | $26,000 | thousands by filing date | |
| HEPION PHARMACEUTICALS INC | 426897104 | COM | 45,800 | $26,000 | thousands by filing date | |
| ALSET EHOME INTERNATIONAL IN | 02116A104 | COM | 86,100 | $25,000 | thousands by filing date | |
| LANDOS BIOPHARMA INC | 515069102 | CMN | 33,900 | $25,000 | thousands by filing date | |
| VIOMI TECHNOLOGY CO LTD | 92762J103 | SPONSORED ADS | 14,200 | $24,000 | thousands by filing date | |
| NEXGEL INC | 65344E107 | COM | 13,850 | $24,000 | thousands by filing date | |
| NATIONAL CINEMEDIA INC | 635309107 | COM | 25,700 | $24,000 | thousands by filing date | |
| RVL PHARMACEUTICALS PLC | G6S41R101 | COM | 17,400 | $24,000 | thousands by filing date | |
| FORTRESS BIOTECH INC | 34960Q109 | COM | 29,000 | $24,000 | thousands by filing date | |
| ZHIHU INC | 98955N108 | ADR | 13,100 | $23,000 | thousands by filing date | |
| MEI PHARMA INC | 55279B202 | COM NEW | 38,704 | $23,000 | thousands by filing date | |
| INMED PHARMACEUTICALS INC | 457637502 | COM NEW | 48,281 | $23,000 | thousands by filing date | |
| CALYXT INC | 13173L107 | COM | 90,800 | $22,000 | thousands by filing date | |
| RAVE RESTAURANT GROUP INC | 754198109 | COM | 19,500 | $21,000 | thousands by filing date | |
| ZOVIO INC | 98979V102 | COMMON STOCK | 21,500 | $21,000 | thousands by filing date | |
| DOMA HOLDINGS INC | 25703A104 | COM | 20,800 | $21,000 | thousands by filing date | |
| HUMANIGEN INC | 444863203 | COM NEW | 11,700 | $21,000 | thousands by filing date | |
| MARKFORGED HOLDING CORPORATI | 57064N102 | COM | 10,900 | $20,000 | thousands by filing date | |
| MOBIQUITY TECHNOLOGIES INC | 60743F508 | COM | 13,700 | $20,000 | thousands by filing date | |
| PAYSIGN INC | 70451A104 | COM | 12,300 | $19,000 | thousands by filing date | |
| CIDARA THERAPEUTICS INC COM NEW | 171757107 | Stock | 38,694 | $19,000 | thousands by filing date | |
| TITAN MED INC | 88830X819 | COM | 37,500 | $19,000 | thousands by filing date | |
| AYTU BIOPHARMA INC | 054754874 | COM | 27,200 | $19,000 | thousands by filing date | |
| OPGEN INC | 68373L307 | COM | 34,500 | $19,000 | thousands by filing date | |
| BIOCEPT INC | 09072V501 | COM | 20,600 | $19,000 | thousands by filing date | |
| Ampio Pharmaceuticals | 03209T109 | COM | 106,916 | $18,000 | thousands by filing date | |
| ELECTROCORE INC | 28531P103 | COM | 35,100 | $18,000 | thousands by filing date | |
| QUMU CORP | 749063103 | COM | 21,800 | $18,000 | thousands by filing date | |
| CYCLACEL PHARMACE 6percent PFDCONV | 23254L603 | Stock | 17,100 | $18,000 | thousands by filing date | |
| FIVE STAR SENIOR LIVING INC | 33832D205 | COM NEW | 14,400 | $17,000 | thousands by filing date | |
| PERSPECTIVE THERAPEUTICS INC | 46489V104 | COM | 54,400 | $17,000 | thousands by filing date | |
| MOLECULIN BIOTECH INC | 60855D200 | COMMON | 11,700 | $17,000 | thousands by filing date | |
| WAITR HLDGS INC | 930752100 | COM | 112,600 | $17,000 | thousands by filing date | |
| SOCIETAL CDMO INC | 75629F109 | COM | 20,500 | $16,000 | thousands by filing date | |
| 180 LIFE SCIENCES CORP | 68236V104 | COM | 18,700 | $16,000 | thousands by filing date | |
| PARAMOUNT GOLD NEV CORP COM | 69924M109 | Stock | 33,100 | $15,000 | thousands by filing date | |
| SONDER HOLDINGS INC | 83542D102 | COM | 14,100 | $15,000 | thousands by filing date | |
| HARBOR CUSTOM DEVELOPMENT IN | 41150T108 | COM | 10,600 | $15,000 | thousands by filing date | |
| DIRTT ENVIRONMENTAL SOLUT LT | 25490H106 | COM | 14,200 | $15,000 | thousands by filing date | |
| ABITS GROUP INC | G6S34K105 | ORDINARY SHARES | 15,200 | $15,000 | thousands by filing date | |
| ACER THERAPEUTICS INC | 00444P108 | CMN | 11,900 | $15,000 | thousands by filing date | |
| CYNERGISTEK INC | 23258P105 | COM | 12,300 | $15,000 | thousands by filing date | |
| BEST INC | 08653C502 | SPONSORED ADS | 12,180 | $14,000 | thousands by filing date | |
| IZEA WORLDWIDE INC COM NEW | 46604H105 | Stock | 14,100 | $13,000 | thousands by filing date | |
| NISUN INTL ENT DVPMT GP CO L | G6593L106 | COM | 20,600 | $13,000 | thousands by filing date | |
| ANTELOPE ENTERPRISE HLDGS LTD SHS NEW | G041JN106 | Stock | 11,900 | $13,000 | thousands by filing date | |
| ELOXX PHARMACEUTICALS INC | 29014R103 | COM | 49,300 | $13,000 | thousands by filing date | |
| ASTROTECH CORP | 046484200 | COM NEW | 30,800 | $13,000 | thousands by filing date | |
| INPIXON | 45790J800 | COM | 78,600 | $13,000 | thousands by filing date | |
| 9F INC SPON ADS NEW | 65442R109 | ADR | 14,200 | $12,000 | thousands by filing date | |
| MIND MEDICINE (MINDMED) INC | 60255C109 | COMMON STOCK-FO | 16,500 | $11,000 | thousands by filing date | |
| ONCOLYTICS BIOTECH INC | 682310875 | COM NEW | 10,900 | $11,000 | thousands by filing date | |
| Cinedigm Corp CL A | 172406209 | COM NEW | 22,600 | $11,000 | thousands by filing date | |
| SEANERGY MARITIME HLDGS CORP | Y73760194 | COM | 13,100 | $11,000 | thousands by filing date | |
| QUOTIENT LTD | G73268107 | SHS | 45,000 | $11,000 | thousands by filing date | |
| NUCANA PLC | 67022C106 | ADR | 15,000 | $11,000 | thousands by filing date | |
| FREELINE THERAPEUTICS HLDGS | 35655L107 | SPONSORED ADS | 12,200 | $11,000 | thousands by filing date | |
| NUWELLIS INC | 67113Y108 | COM | 18,500 | $11,000 | thousands by filing date | |
| XINYUAN REAL ESTATE CO LTD | 98417P105 | SPONS ADR | 12,400 | $10,000 | thousands by filing date | |
| TANTECH HLDGS LTD | G8675X123 | SHS NEW | 34,330 | $10,000 | thousands by filing date | |
| GENIUS BRANDS INTERNATIONAL INC | 37229T301 | COMMON STOCK | 12,400 | $9,000 | thousands by filing date | |
| RETO ECO SOLUTIONS INC | G75271109 | COM | 11,100 | $9,000 | thousands by filing date | |
| GUARDFORCE AI CO LTD | G4236L112 | SHS | 20,100 | $9,000 | thousands by filing date | |
| EARGO INC | 270087109 | COM | 12,300 | $9,000 | thousands by filing date | |
| SMART FOR LIFE INC | 83204U103 | COMMON STOCK | 17,700 | $9,000 | thousands by filing date | |
| PHASEBIO PHARMACEUTICALS INC | 717224109 | COM | 12,700 | $8,000 | thousands by filing date | |
| CBDMD INC | 12482W101 | COM | 17,800 | $8,000 | thousands by filing date | |
| TREVENA INC | 89532E109 | COM | 20,000 | $8,000 | thousands by filing date | |
| CONFORMIS INC | 20717E101 | COM | 23,200 | $8,000 | thousands by filing date | |
| UPHEALTH INC | 91532B101 | COM | 11,300 | $7,000 | thousands by filing date | |
| SCWORX CORP COM | 78396V109 | Stock | 10,600 | $7,000 | thousands by filing date | |
| ACORDA THERAPEUTICS INC COM | 00484M601 | Stock | 14,400 | $7,000 | thousands by filing date | |
| LIMINAL BIOSCIENCES INC | 53272L103 | COM | 10,800 | $6,000 | thousands by filing date | |
| EMBARK TECHNOLOGY INC | 29079J103 | COM | 12,000 | $6,000 | thousands by filing date | |
| SENESTECH INC | 81720R208 | COM NEW | 11,900 | $6,000 | thousands by filing date | |
| FEDNAT HOLDING COMPANY | 31431B109 | Common Stock | 14,600 | $5,000 | thousands by filing date | |
| GOLDEN MINERALS COMPANY | 381119106 | COM | 14,800 | $5,000 | thousands by filing date | |
| CHINA PHARMA HOLDINGS INC | 16941T104 | COM | 23,600 | $5,000 | thousands by filing date | |
| DSS INC | 26253C102 | COM | 13,600 | $5,000 | thousands by filing date | |
| SINTX TECHNOLOGIES INC | 829392307 | COM NEW | 12,600 | $5,000 | thousands by filing date | |
| MISSFRESH LTD | 60500F105 | ADS | 18,000 | $5,000 | thousands by filing date | |
| STEALTH BIOTHERAPEUTICS CORP SPONSORED ADS | 85789A105 | Stock | 15,400 | $4,000 | thousands by filing date | |
| ABEONA THERAPEUTICS INC | 00289Y107 | COM | 13,800 | $3,000 | thousands by filing date | |
| GREAT PANTHER MINING | 39115V101 | COM | 22,300 | $3,000 | thousands by filing date | |
| AETERNA ZENTARIS INC | 007975402 | COM | 15,700 | $3,000 | thousands by filing date | |
| DIGITAL BRANDS GROUP INC | 25401N101 | COM | 11,200 | $2,000 | thousands by filing date | |
| ENJOY TECHNOLOGY INC | 29335V106 | COM | 11,500 | $2,000 | thousands by filing date | |
| ENVERIC BIOSCIENCES INC | 29405E109 | COM NEW | 10,400 | $2,000 | thousands by filing date |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0000919574-22-005031 | this filing | 2022-08-15 | acceptance time not in the bulk data set |