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13F-HR filed by TWO SIGMA INVESTMENTS, LP

TWO SIGMA INVESTMENTS, LP filed this 13F-HR for the quarter ended 2022-03-31, filed 2022-05-16, with 2,540 holding rows worth $33,883,184,000.

Accession
0000919574-22-003439
Filed
2022-05-16
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q1 2022

A holdings report, 2,540 entries on the cover page, a total value of $33,883,184,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $33,883,184,000 with VALUE read as thousands by filing date, 13F file number 028-10385. The quarter's positions are built on this report. The resolved quarter.

Other managers

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
CATALYST BIOSCIENCES INC14888D208COM62,729$41,000thousands by filing date
SOC TELEMED78472F101COM13,661$41,000thousands by filing date
CONCERT PHARMACEUTICALS INC206022105COM12,000$40,000thousands by filing date
AETHLON MED INC00808Y307COM27,717$40,000thousands by filing date
FLOTEK INDS INC DEL343389102COM30,500$38,000thousands by filing date
REVELATION BIOSCIENCES INC76135L101COM32,540$37,000thousands by filing date
INMED PHARMACEUTICALS INC457637502COM NEW39,700$37,000thousands by filing date
QUOTIENT LTDG73268107SHS30,415$36,000thousands by filing date
APREA THERAPEUTICS INC03836J102COM18,610$35,000thousands by filing date
REGULUS THERAPEUTICS INC75915K200COM NEW114,440$34,000thousands by filing date
TOKYO LIFESTYLE CO LTD SPONSORED ADS98741L101ADR15,704$33,000thousands by filing date
EDESA BIOTECH INC27966L108COM11,106$33,000thousands by filing date
GRUPO SUPERVIELLE S.A.40054A108CMN15,144$31,000thousands by filing date
GEOVAX LABS INC373678507COM27,323$31,000thousands by filing date
The Very Good Food Company Inc COM88340B109Common Stock58,286$30,000thousands by filing date
TRILOGY METALS INC89621C105COMMON STOCK27,896$29,000thousands by filing date
AMERICAN SHARED HOSPITAL SVC029595105COM11,123$26,000thousands by filing date
MARCHEX INC56624R108CMN11,471$26,000thousands by filing date
GREAT PANTHER MINING39115V101COM99,724$25,000thousands by filing date
SUPERIOR DRILLING PRODS INC868153107COM23,500$25,000thousands by filing date
SIGILON THERAPEUTICS INC82657L107COM15,559$23,000thousands by filing date
ANGION BIOMEDICA CORP03476J107COM10,727$23,000thousands by filing date
ASPEN GROUP INC04530L203COM NEW14,366$23,000thousands by filing date
PALISADE BIO INC696389105COM21,560$23,000thousands by filing date
SENSEONICS HLDGS INC81727U105COM11,172$22,000thousands by filing date
RA MED SYS INC74933X203COM53,768$22,000thousands by filing date
WISA TECHNOLOGIES INC86633R203COM NEW16,247$20,000thousands by filing date
Ohr Pharmaceutical Inc64132K102COM10,222$19,000thousands by filing date
STATERA BIOPHARMA INC857561104COM58,519$18,000thousands by filing date
CIDARA THERAPEUTICS INC COM NEW171757107Stock20,532$17,000thousands by filing date
PENNSYLVANIA RL ESTATE INVT709102107SH BEN INT26,480$17,000thousands by filing date
TIMBER PHARMACEUTICALS INC887080109COM43,605$17,000thousands by filing date
E-HOME HOUSEHOLD SVC HLDGS LG2952X104ORD SHS19,075$14,000thousands by filing date
METACRINE INC59101E103COM23,035$14,000thousands by filing date
BAOSHENG MEDIA GROUP HLDNG LG08908108SHS24,188$14,000thousands by filing date
ELOXX PHARMACEUTICALS INC29014R103COM23,079$13,000thousands by filing date
ZHANGMEN EDUCATION INC.98955H200SPONSORED ADS10,307$13,000thousands by filing date
MISSFRESH LTD60500F105ADS12,379$11,000thousands by filing date
CNS PHARMACEUTICALS INC18978H102COM25,143$9,000thousands by filing date
Kelso Technologies Inc48826D201COM17,024$8,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0000919574-22-003439this filing2022-05-16acceptance time not in the bulk data set