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13F-HR filed by TWO SIGMA SECURITIES, LLC

TWO SIGMA SECURITIES, LLC filed this 13F-HR for the quarter ended 2022-03-31, filed 2022-05-16, with 2,073 holding rows worth $2,840,021,000.

Accession
0000919574-22-003437
Filed
2022-05-16
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q1 2022

A holdings report, 2,073 entries on the cover page, a total value of $2,840,021,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $2,840,021,000 with VALUE read as thousands by filing date, 13F file number 028-16740. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
SURGALIGN HOLDINGS INC86882C105COM55,344$17,000thousands by filing date
MEREO BIOPHARMA GROUP PLC589492107CMN14,000$16,000thousands by filing date
SPECTRUM PHARMACEUTICALS INC84763A108COM12,226$16,000thousands by filing date
SELECTA BIOSCIENCES INC816212104COM12,872$16,000thousands by filing date
PINTEC TECHNOLOGY HLDGS LTD SPONSORED ADS72352G107ADR24,534$16,000thousands by filing date
COHBAR INC COM NEW19249J109Stock50,261$16,000thousands by filing date
NANTHEALTH INC630104107CMN21,809$16,000thousands by filing date
BORQS TECHNOLOGIES INCG1466B103SHS71,023$16,000thousands by filing date
IT TECH PACKAGING INC46527C100COM NEW71,140$16,000thousands by filing date
CYBIN INC23256X100COM18,281$15,000thousands by filing date
DUNXIN FINL HLDGS LTD26605Q106SPONSORED ADS22,911$15,000thousands by filing date
SOLIGENIX INC834223307COM19,988$15,000thousands by filing date
ZW DATA ACTION TECHNOLOGS IN98880R109COM20,698$15,000thousands by filing date
BIMI INTERNATIONAL MEDICAL I05552Q202COM NEW11,075$15,000thousands by filing date
AVINO SILVER & GOLD MINES LT053906103COM14,891$14,000thousands by filing date
IGC PHARMA INC45408X308COM NEW14,436$14,000thousands by filing date
The Very Good Food Company Inc COM88340B109Common Stock28,269$14,000thousands by filing date
MINERVA NEUROSCIENCES INC COM NEW603380106Stock17,123$14,000thousands by filing date
Cinedigm Corp CL A172406209COM NEW17,415$14,000thousands by filing date
E-HOME HOUSEHOLD SVC HLDGS LG2952X104ORD SHS19,401$14,000thousands by filing date
METROMILE INC591697107COM10,724$14,000thousands by filing date
HUIZE HLDG LTD44473E105SPONSORED ADS10,524$14,000thousands by filing date
FSD PHARMA INC35954B206CL B SUB VTG16,457$14,000thousands by filing date
EXICURE INC30205M101COM70,887$14,000thousands by filing date
INFOBIRD CO LTDG47724102SHS20,182$14,000thousands by filing date
AMERICAS GOLD AND SILVER COR03062D100COM11,709$13,000thousands by filing date
SAVARA INC805111101COM10,018$13,000thousands by filing date
PROQR THERAPEUTICS NVN71542109SHS EURO13,941$13,000thousands by filing date
FLOTEK INDS INC DEL343389102COM10,157$13,000thousands by filing date
GREAT PANTHER MINING39115V101COM52,487$13,000thousands by filing date
MCEWEN MNG INC58039P107COM14,902$13,000thousands by filing date
CREATIVE REALITIES INC22530J200COM15,632$13,000thousands by filing date
NUCANA PLC67022C106ADR12,642$13,000thousands by filing date
JUPAI HLDGS LTD48205B107ADS18,121$13,000thousands by filing date
VTV THERAPEUTICS INC CL A918385105Stock18,559$13,000thousands by filing date
ZHANGMEN EDUCATION INC.98955H200SPONSORED ADS10,343$13,000thousands by filing date
ACELRX PHARMACEUTICALS INC00444T100COM42,915$12,000thousands by filing date
CREATD INC225265107COM10,285$12,000thousands by filing date
THERIVA BIOLOGICS INC COM NEW87164U201Stock37,786$11,000thousands by filing date
NEPTUNE WELLNESS SOLUTIONS I64079L105COM50,085$11,000thousands by filing date
THERMOGENESIS HLDGS INC88362L100COM16,083$11,000thousands by filing date
SESEN BIO INC817763105COM17,279$10,000thousands by filing date
ORAGENICS INC684023302COM PAR30,263$10,000thousands by filing date
RENOVARE ENVIRONMENTAL I09074B107COM17,297$10,000thousands by filing date
GREENLANE HLDGS INC395330103CL A18,645$10,000thousands by filing date
PLANET GREEN HLDGS CORP72703U102COM10,973$10,000thousands by filing date
SENESTECH INC81720R208COM NEW13,336$10,000thousands by filing date
ABEONA THERAPEUTICS INC00289Y107COM27,103$9,000thousands by filing date
NEUROBO PHARMACEUTICALS INC64132R107COM10,204$9,000thousands by filing date
ARTELO BIOSCIENCES INC04301G201COM NEW18,227$8,000thousands by filing date
JAGUAR HEALTH INC47010C607COM10,631$8,000thousands by filing date
ALTERITY THERAPEUTICS LTD02155X106SPONSORED ADR10,206$8,000thousands by filing date
TANTECH HLDGS LTDG8675X123SHS NEW16,901$8,000thousands by filing date
THERAPEUTICSMD INC88338N107COM17,701$7,000thousands by filing date
SIO GENE THERAPIES INC829399104COM10,918$7,000thousands by filing date
GREENPRO CAP CORP COM NEW39540F101Stock15,608$7,000thousands by filing date
CHECK CAP LTDM2361E203SHS18,779$7,000thousands by filing date
EVOFEM BIOSCIENCES INC30048L104COM17,944$6,000thousands by filing date
WAITR HLDGS INC930752100COM14,869$6,000thousands by filing date
CHINA PHARMA HOLDINGS INC16941T104COM13,438$5,000thousands by filing date
BIOLASE INC090911207COM NEW14,175$5,000thousands by filing date
SALARIUS PHARMACEUTICALS INC79400X107COM NEW12,435$5,000thousands by filing date
BIT BROTHER LIMITEDG1144D109SHS14,812$5,000thousands by filing date
BOQII HLDG LTD09950L104SPONSORED ADS11,230$5,000thousands by filing date
SENMIAO TECHNOLOGY LTD817225105COM21,972$5,000thousands by filing date
TIMBER PHARMACEUTICALS INC887080109COM11,531$4,000thousands by filing date
AGILE THERAPEUTICS INC00847L100COM18,526$4,000thousands by filing date
AKERNA CORP00973W110WTS23,718$4,000thousands by filing date
DIFFUSION PHARMACEUTICALS IN253748305COM PAR15,457$4,000thousands by filing date
AEQUI ACQUISITION CORP00775W110*W EXP 11/30/20215,219$3,000thousands by filing date
LANDSEA HOMES CORP51509P111*W EXP 01/08/20214,750$3,000thousands by filing date
BROADMARK RLTY CAP INC11135B118*W EXP 11/15/20220,240$2,000thousands by filing date
LION GROUP HOLDING LTD53620U110*W EXP 06/16/20212,184$1,000thousands by filing date

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0000919574-22-003437this filing2022-05-16acceptance time not in the bulk data set