13F-HR filed by TWO SIGMA ADVISERS, LP
TWO SIGMA ADVISERS, LP filed this 13F-HR for the quarter ended 2021-12-31, filed 2022-02-14, with 2,591 holding rows worth $39,927,327,000.
- Accession
- 0000919574-22-001505
- Filer
- CIK 1478735
- Filed
- 2022-02-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2021
A holdings report, 2,591 entries on the cover page, a total value of $39,927,327,000 stated on the cover page (in dollars after the unit check, H1), rows summing to $39,927,327,000 with VALUE read as thousands by filing date, 13F file number 028-14367. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerTWO SIGMA ABSOLUTE RETURN PORTFOLIO, LLC028-15367
- included managerTWO SIGMA ACTIVE EXTENSION U.S. ALL CAP EQUITY PORTFOLIO, LLC028-15404
- included managerTwo Sigma Active Extension U.S. Small Cap Equity Fund, LP028-15364
- included managerTwo Sigma Macro Portfolio, LLC028-16751
- included managerTwo Sigma World Core Fund, LP028-17350
- included managerTwo Sigma Equity Risk Premia Portfolio, LLC028-17346
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| VISIONSYS AI INC | 876108200 | SPONSORED ADS | 20,599 | $38,000 | thousands by filing date | |
| CYCLO THERAPEUTICS INC | 23254X201 | Common Stock | 10,200 | $38,000 | thousands by filing date | |
| METACRINE INC | 59101E103 | COM | 55,900 | $38,000 | thousands by filing date | |
| YUMANITY THERAPEUTICS INC | 98872L102 | COM | 12,700 | $38,000 | thousands by filing date | |
| HALL OF FAME RESORT & ENTMT | 40619L102 | COM | 24,300 | $37,000 | thousands by filing date | |
| MEDALIST DIVERSIFIED REIT IN | 58403P105 | COM | 31,000 | $37,000 | thousands by filing date | |
| KORU MEDICAL SYSTEMS INC | 759910102 | COMMON STOCK | 12,000 | $36,000 | thousands by filing date | |
| DYNATRONICS CORP | 268157401 | COM NEW | 35,700 | $36,000 | thousands by filing date | |
| DIGITAL BRANDS GROUP INC | 25401N101 | COM | 15,500 | $36,000 | thousands by filing date | |
| AVINGER INC | 053734604 | COM | 79,700 | $36,000 | thousands by filing date | |
| BEST INC | 08653C106 | SPONSORED ADS | 40,800 | $35,000 | thousands by filing date | |
| COCRYSTAL PHARMA INC | 19188J300 | CMN | 53,700 | $35,000 | thousands by filing date | |
| MOLECULIN BIOTECH INC | 60855D200 | COMMON | 18,400 | $34,000 | thousands by filing date | |
| SURGALIGN HOLDINGS INC | 86882C105 | COM | 47,700 | $34,000 | thousands by filing date | |
| VIOMI TECHNOLOGY CO LTD | 92762J103 | SPONSORED ADS | 13,500 | $33,000 | thousands by filing date | |
| AURORA MOBILE LTD | 051857100 | ADS | 32,100 | $33,000 | thousands by filing date | |
| BTCS INC | 05581M404 | CMN | 10,100 | $32,000 | thousands by filing date | |
| BROADWAY FINL CORP DEL | 111444105 | COM | 14,000 | $32,000 | thousands by filing date | |
| WIMI HOLOGRAM CLOUD INC | 97264L100 | SPON ADS CL B | 10,400 | $32,000 | thousands by filing date | |
| BROADWIND INC | 11161T207 | CMN | 16,400 | $31,000 | thousands by filing date | |
| XENETIC BIOSCIENCES INC | 984015503 | COM | 24,400 | $31,000 | thousands by filing date | |
| NUVERRA ENVIRONMENTAL SOLUTI | 67091K302 | CMN | 10,200 | $31,000 | thousands by filing date | |
| KALA BIO INC COM | 483119103 | Stock | 24,800 | $30,000 | thousands by filing date | |
| OPGEN INC | 68373L307 | COM | 30,000 | $30,000 | thousands by filing date | |
| INPIXON | 45790J800 | COM | 49,200 | $30,000 | thousands by filing date | |
| ZOVIO INC | 98979V102 | COMMON STOCK | 22,000 | $28,000 | thousands by filing date | |
| XINYUAN REAL ESTATE CO LTD | 98417P105 | SPONS ADR | 44,600 | $28,000 | thousands by filing date | |
| ASPEN GROUP INC | 04530L203 | COM NEW | 11,900 | $28,000 | thousands by filing date | |
| VIVEVE MED INC | 92852W501 | COM | 24,300 | $28,000 | thousands by filing date | |
| STAR EQUITY HOLDINGS INC | 85513Q103 | COMMON | 11,000 | $28,000 | thousands by filing date | |
| IBIO INC | 451033203 | COM NEW | 48,800 | $27,000 | thousands by filing date | |
| GENOCEA BIOSCIENCES INC | 372427401 | COMMON STOCK | 22,677 | $26,000 | thousands by filing date | |
| IDERA PHARMACEUTICALS INC | 45168K405 | COM PAR | 46,347 | $26,000 | thousands by filing date | |
| NLS PHARMACEUTICS LTD COM NEW | H57830103 | Stock | 22,800 | $25,000 | thousands by filing date | |
| GENPREX INC | 372446104 | COM | 18,800 | $25,000 | thousands by filing date | |
| ONCTERNAL THERAPEUTICS INC | 68236P107 | COM | 10,800 | $25,000 | thousands by filing date | |
| SENMIAO TECHNOLOGY LTD | 817225105 | COM | 67,700 | $25,000 | thousands by filing date | |
| MEREO BIOPHARMA GROUP PLC | 589492107 | CMN | 15,100 | $24,000 | thousands by filing date | |
| AYTU BIOPHARMA INC | 054754874 | COM | 17,430 | $24,000 | thousands by filing date | |
| RETO ECO SOLUTIONS INC | G75271109 | COM | 13,900 | $24,000 | thousands by filing date | |
| PROFESSIONAL DIVERSITY NET I | 74312Y202 | COM | 24,800 | $24,000 | thousands by filing date | |
| The Very Good Food Company Inc COM | 88340B109 | Common Stock | 31,700 | $23,000 | thousands by filing date | |
| 9F INC SPON ADS NEW | 65442R109 | ADR | 20,100 | $22,000 | thousands by filing date | |
| ANTELOPE ENTERPRISE HLDGS LTD SHS NEW | G041JN106 | Stock | 13,100 | $21,000 | thousands by filing date | |
| MARRONE BIO INNOVATIONS INC | 57165B106 | COM | 29,500 | $21,000 | thousands by filing date | |
| STEALTH BIOTHERAPEUTICS CORP SPONSORED ADS | 85789A105 | Stock | 25,200 | $21,000 | thousands by filing date | |
| CYNERGISTEK INC | 23258P105 | COM | 14,100 | $20,000 | thousands by filing date | |
| SONIM TECHNOLOGIES INC | 83548F200 | COM NEW | 21,100 | $19,000 | thousands by filing date | |
| EASTSIDE DISTILLING INC | 277802302 | COM | 10,600 | $19,000 | thousands by filing date | |
| IZEA WORLDWIDE INC COM NEW | 46604H105 | Stock | 12,600 | $17,000 | thousands by filing date | |
| GUARDION HEALTH SCIENCES INC | 40145Q401 | COM | 27,000 | $17,000 | thousands by filing date | |
| TEAM INC | 878155100 | COM | 15,215 | $17,000 | thousands by filing date | |
| TIMBER PHARMACEUTICALS INC | 887080109 | COM | 45,400 | $17,000 | thousands by filing date | |
| INVIVO THERAPEUTICS HLDGS CORP COM | 46186M506 | Stock | 37,400 | $17,000 | thousands by filing date | |
| AETERNA ZENTARIS INC | 007975402 | COM | 44,400 | $16,000 | thousands by filing date | |
| GOLDMINING INC | 38149E101 | COM | 12,600 | $15,000 | thousands by filing date | |
| PERSPECTIVE THERAPEUTICS INC | 46489V104 | COM | 39,600 | $15,000 | thousands by filing date | |
| AIR INDS GROUP COM | 00912N205 | Stock | 16,100 | $15,000 | thousands by filing date | |
| CHINA PHARMA HOLDINGS INC | 16941T104 | COM | 31,600 | $15,000 | thousands by filing date | |
| Kintara Therapeutics, Inc. | 49720K101 | Equities | 30,100 | $15,000 | thousands by filing date | |
| SCWORX CORP COM | 78396V109 | Stock | 10,700 | $14,000 | thousands by filing date | |
| PALISADE BIO INC | 696389105 | COM | 10,500 | $14,000 | thousands by filing date | |
| CHINA SXT PHARMACEUTICALS IN | G2161P116 | ORD SHS NEW | 20,400 | $13,000 | thousands by filing date | |
| LAIX INC | 50736W105 | ADS | 23,860 | $13,000 | thousands by filing date | |
| FOUR SEASONS ED CAYMAN INC SPON ADS | 35101A101 | ADR | 17,300 | $12,000 | thousands by filing date | |
| DSS INC | 26253C102 | COM | 17,900 | $12,000 | thousands by filing date | |
| SENESTECH INC | 81720R208 | COM NEW | 12,400 | $12,000 | thousands by filing date | |
| FARMMI INC SHS NEW | G33277107 | Stock | 56,100 | $12,000 | thousands by filing date | |
| ABEONA THERAPEUTICS INC | 00289Y107 | COM | 31,400 | $11,000 | thousands by filing date | |
| GREAT PANTHER MINING | 39115V101 | COM | 51,600 | $11,000 | thousands by filing date | |
| REMARK HLDGS INC | 75955K102 | COM | 11,500 | $11,000 | thousands by filing date | |
| SINTX TECHNOLOGIES INC | 829392307 | COM NEW | 17,300 | $11,000 | thousands by filing date | |
| PHOENIX NEW MEDIA LTD | 71910C103 | SPONSORED ADR | 11,200 | $10,000 | thousands by filing date | |
| LUOKUNG TECHNOLOGY CORP | G56981106 | SHS | 16,600 | $10,000 | thousands by filing date | |
| HISTOGEN INC | 43358Y103 | COM | 29,000 | $10,000 | thousands by filing date | |
| PULMATRIX INC COM | 74584P202 | Stock | 20,000 | $9,000 | thousands by filing date | |
| POLARITYTE INC | 731094108 | COM | 15,600 | $9,000 | thousands by filing date | |
| ROCKWELL MED INC | 774374102 | COM | 19,000 | $8,000 | thousands by filing date | |
| CHINA NATURAL RESOURCES INC | G2110U109 | COM | 13,100 | $8,000 | thousands by filing date | |
| KAIVAL BRNDS INNOVATNS GRP I | 483104204 | COM NEW | 11,300 | $8,000 | thousands by filing date | |
| ARTELO BIOSCIENCES INC | 04301G201 | COM NEW | 16,000 | $8,000 | thousands by filing date | |
| NEOVASC INC | 64065J304 | COM | 17,300 | $8,000 | thousands by filing date | |
| CORBUS PHARMACEUTICALS HLDGS | 21833P103 | COM | 11,300 | $7,000 | thousands by filing date | |
| TYME TECHNOLOGIES INC COM | 90238J103 | Stock | 10,300 | $6,000 | thousands by filing date | |
| ITERUM THERAPEUTICS PLC SHS NEW | G6333L101 | Stock | 14,300 | $6,000 | thousands by filing date | |
| NOVABAY PHARMACEUTICALS INC | 66987P201 | COM NEW | 16,400 | $6,000 | thousands by filing date | |
| AILERON THERAPEUTICS INC COM NEW | 00887A105 | Stock | 11,300 | $6,000 | thousands by filing date | |
| GOLDEN MINERALS COMPANY | 381119106 | COM | 14,500 | $5,000 | thousands by filing date | |
| MOGU INC SPON ADS | 608012100 | ADR | 11,600 | $4,000 | thousands by filing date | |
| CHINA JO-JO DRUGSTORES INC | G2124G104 | ORD SHS | 10,900 | $4,000 | thousands by filing date | |
| EROS INTL PLC | G3788M114 | SHS NEW | 10,700 | $3,000 | thousands by filing date |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0000919574-22-001505 | this filing | 2022-02-14 | acceptance time not in the bulk data set |