13F-HR filed by TWO SIGMA INVESTMENTS, LP
TWO SIGMA INVESTMENTS, LP filed this 13F-HR for the quarter ended 2025-06-30, filed 2025-08-14, with 3,150 holding rows worth $56,473,570,273.
- Accession
- 0000899140-25-000964
- Filer
- CIK 1179392
- Filed
- 2025-08-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q2 2025
A holdings report, 3,150 entries on the cover page, a total value of $56,473,570,273 stated on the cover page (in dollars after the unit check, H1), rows summing to $56,473,570,273 with VALUE read as dollars as filed, 13F file number 028-10385. The quarter's positions are built on this report. The resolved quarter.
Other managers
- included managerTWO SIGMA EQUITY PORTFOLIO LLC028-10704
- included managerTWO SIGMA SPECTRUM PORTFOLIO, LLC028-11144
- included managerTwo Sigma Futures Portfolio, LLC028-16011
- included managerTWO SIGMA HORIZON PORTFOLIO, LLC028-15356
- included managerTwo Sigma Equity Spectrum Portfolio, LLC028-20138
- included managerTwo Sigma Blazar Portfolio, LLC028-23019
- included managerTwo Sigma Navigator Portfolio, LLC028-23021
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| ALTO NEUROSCIENCE INC COM SHS | 02157Q109 | Stock | 44,735 | $98,417 | dollars as filed | |
| INDUSTRIAL LOGISTICS PPTYS T | 456237106 | COM SHS BEN INT | 21,600 | $98,280 | dollars as filed | |
| IMMUNOPRECISE ANTIBODIES LTDCOM NEW | 45257F200 | cs | 90,855 | $96,306 | dollars as filed | |
| THE ARENA GROUP HOLDINGS INC | 040044109 | CMN | 15,469 | $95,908 | dollars as filed | |
| INTEST CORP | 461147100 | COMMON STOCK | 13,043 | $94,953 | dollars as filed | |
| ELEVATION ONCOLOGY INC COM | 28623U101 | Stock | 254,295 | $93,352 | dollars as filed | |
| DESTINATION XL GROUP INC | 25065K104 | COM | 82,930 | $92,052 | dollars as filed | |
| EPSILON ENERGY LTD | 294375209 | COMMON STOCK | 12,166 | $89,785 | dollars as filed | |
| LYELL IMMUNOPHARMA INC COM NEW | 55083R203 | Stock | 10,059 | $88,922 | dollars as filed | |
| COMPANHIA SIDERURGICA NACION | 20440W105 | SPONSORED ADR | 62,800 | $87,920 | dollars as filed | |
| HARVARD BIOSCIENCE INC | 416906105 | COM | 197,785 | $87,777 | dollars as filed | |
| ALIGOS THERAPEUTICS INC | 01626L204 | COM NEW | 12,073 | $87,046 | dollars as filed | |
| FORTRESS BIOTECH INC | 34960Q307 | COM NEW | 45,832 | $85,248 | dollars as filed | |
| RIBBON COMMUNICATIONS INC | 762544104 | COMMON STOCK | 20,811 | $83,452 | dollars as filed | |
| SOLARIS RES INC | 83419D201 | COM NEW | 18,114 | $82,962 | dollars as filed | |
| INMUNE BIO INC | 45782T105 | COM | 35,591 | $82,215 | dollars as filed | |
| SUTRO BIOPHARMA INC | 869367102 | COM | 115,068 | $82,147 | dollars as filed | |
| CODEXIS INC | 192005106 | COM | 33,648 | $82,101 | dollars as filed | |
| FLEXIBLE SOLUTIONS INTL INC | 33938T104 | COM | 16,723 | $81,107 | dollars as filed | |
| PULMONX CORP | 745848101 | COM | 30,899 | $80,028 | dollars as filed | |
| HIMALAYA SHIPPING LTD ORD SHS | G4660A103 | Stock | 13,837 | $79,839 | dollars as filed | |
| NIOCORP DEVS LTD | 654484609 | COM NEW | 34,071 | $79,385 | dollars as filed | |
| IKENA ONCOLOGY INC | 45175G108 | COM | 58,957 | $79,002 | dollars as filed | |
| SIFY TECHNOLOGIES AMERICAN DEPOSIT | 82655M206 | EQUITY | 17,136 | $78,654 | dollars as filed | |
| B. RILEY FINANCIAL INC | 05580M108 | COM | 26,100 | $77,517 | dollars as filed | |
| AYTU BIOPHARMA INC | 054754858 | COM | 35,035 | $76,376 | dollars as filed | |
| MURAL ONCOLOGY PUB LTD CO | G63365103 | ORD SHS | 30,598 | $75,577 | dollars as filed | |
| INDONESIA ENERGY CORP LTD | G4760X102 | ORD SHS | 25,342 | $75,519 | dollars as filed | |
| TAYSHA GENE THERAPIES INC | 877619106 | COMMON STOCK | 32,682 | $75,495 | dollars as filed | |
| KYNTRA BIO INC | 31572Q881 | COM NEW | 14,111 | $74,788 | dollars as filed | |
| RESOURCES CONNECTION INC | 76122Q105 | COM | 13,921 | $74,756 | dollars as filed | |
| TEADS HLDG CO | 69002R103 | COM | 29,822 | $73,959 | dollars as filed | |
| GENELUX CORP | 36870H103 | COMMON STOCK | 24,992 | $71,727 | dollars as filed | |
| PEPGEN INC COM | 713317105 | Stock | 63,740 | $70,751 | dollars as filed | |
| AIRSCULPT TECHNOLOGIES INC | 009496100 | COMMON STOCK | 14,541 | $70,233 | dollars as filed | |
| PRECISION BIOSCIENCES INC | 74019P207 | COM NEW | 16,363 | $68,725 | dollars as filed | |
| AUTHID INC | 46264C305 | COM | 12,926 | $68,379 | dollars as filed | |
| LG DISPLAY CO LTD SPONS ADR REP | 50186V102 | ADR | 19,713 | $67,418 | dollars as filed | |
| ALTO INGREDIENTS INC | 021513106 | COMMON STOCK | 58,595 | $67,384 | dollars as filed | |
| TPI Composites Inc | 87266J104 | Common Stock | 76,438 | $65,683 | dollars as filed | |
| ACTINIUM PHARMACEUTICALS | 00507W206 | COM | 46,545 | $65,163 | dollars as filed | |
| BTCS INC | 05581M404 | CMN | 29,608 | $65,138 | dollars as filed | |
| AURORA CANNABIS INC COM | 05156X850 | Stock | 15,307 | $64,902 | dollars as filed | |
| FTC SOLAR INC | 30320C301 | CMN | 14,285 | $64,711 | dollars as filed | |
| SMART SAND INC | 83191H107 | COM | 32,013 | $64,346 | dollars as filed | |
| AVALO THERAPEUTICS INC | 05338F306 | COMMON STOCK | 12,889 | $64,316 | dollars as filed | |
| EGAIN CORP | 28225C806 | COM NEW | 10,135 | $63,344 | dollars as filed | |
| TETRA TECHNOLOGIES INC DEL | 88162F105 | COM | 18,766 | $63,054 | dollars as filed | |
| IMMUNEERING CORP | 45254E107 | CLASS A COM | 18,553 | $62,524 | dollars as filed | |
| AC IMMUNE SA | H00263105 | SHS | 30,690 | $62,301 | dollars as filed | |
| ONKURE THERAPEUTICS INC | 68277Q105 | COM CL A | 25,862 | $61,810 | dollars as filed | |
| SHATTUCK LABS INC | 82024L103 | COMMON STOCK | 76,934 | $60,916 | dollars as filed | |
| NANO DIMENSION LTD | 63008G203 | SPONSORD ADS NEW | 37,596 | $60,906 | dollars as filed | |
| RICHTECH ROBOTICS INC | 765504105 | CL B | 31,044 | $60,536 | dollars as filed | |
| AMESITE INC | 031094204 | CMN | 21,579 | $58,048 | dollars as filed | |
| RELMADA THERAPEUTICS INC | 75955J402 | COMMON STOCK | 95,417 | $57,279 | dollars as filed | |
| TOP FINANCIAL GROUP LTD | G989A6102 | SHS CL A | 46,610 | $57,097 | dollars as filed | |
| RIVERVIEW BANCORP INC | 769397100 | COM | 10,056 | $55,308 | dollars as filed | |
| D-MARKET ELECTR SVCS TRY 0.2 | 23292B104 | SPONSORED ADS | 20,238 | $54,643 | dollars as filed | |
| Xilio Therapeutics Inc. | 98422T100 | COM | 78,032 | $53,054 | dollars as filed | |
| GLIMPSE GROUP INC | 37892C106 | COM | 37,928 | $51,582 | dollars as filed | |
| WEREWOLF THERAPEUTICS INC | 95075A107 | CMN | 45,422 | $49,510 | dollars as filed | |
| ZEVIA PBC | 98955K104 | CL A | 15,232 | $49,047 | dollars as filed | |
| CURRENC GROUP INC | G47862100 | CL A ORD SHS | 59,536 | $48,516 | dollars as filed | |
| VAXART INC NEW | 92243A200 | COM | 106,929 | $48,332 | dollars as filed | |
| BIG 5 SPORTING GOODS CORP | 08915P101 | COM | 33,844 | $48,058 | dollars as filed | |
| MYSEUMAI INC | 23816M206 | COM NEW | 18,857 | $47,897 | dollars as filed | |
| SNOW LAKE RES LTD | 83336J307 | COM | 13,011 | $47,100 | dollars as filed | |
| VERRICA PHARMACEUTICALS INC | 92511W108 | COM | 87,293 | $46,274 | dollars as filed | |
| SURF AIR MOBILITY INC | 868927203 | CMN | 12,533 | $46,247 | dollars as filed | |
| LAVA THERAPEUTICS NV | N51517105 | SHS | 34,412 | $45,424 | dollars as filed | |
| VISIONARY HOLDINGS INC | 92838F200 | COM NEW | 28,535 | $45,371 | dollars as filed | |
| SCANTECH AI SYS INC | 80603V104 | COM | 67,376 | $45,027 | dollars as filed | |
| REPARE THERAPEUTICS INC | 760273102 | COM | 32,255 | $44,834 | dollars as filed | |
| AMPLITECH GROUP INC | 03211Q200 | COM | 20,961 | $44,437 | dollars as filed | |
| GOLD RESOURCE CORP | 38068T105 | COMMON STOCK | 72,055 | $43,954 | dollars as filed | |
| PROTARA THERAPEUTICS INC | 74365U107 | COM STK | 14,404 | $43,644 | dollars as filed | |
| ODYSSEY MARINE EXPL INC | 676118201 | COM NEW | 36,884 | $43,523 | dollars as filed | |
| INOTIV INC | 45783Q100 | COM | 23,802 | $43,320 | dollars as filed | |
| UNITI GROUP INC | 91325V108 | COM | 10,000 | $43,200 | dollars as filed | put |
| GREENLAND TECHNOLOGIES HLDG | G4095T107 | ORD SHS CL A | 21,432 | $42,650 | dollars as filed | |
| SIGMATRON INTL INC | 82661L101 | COM | 14,180 | $42,186 | dollars as filed | |
| ProKidney Corp | G7S53R104 | Common Stock | 70,699 | $41,861 | dollars as filed | |
| COMPASS THERAPEUTICS INC | 20454B104 | COM | 16,097 | $41,852 | dollars as filed | |
| ADVERUM BIOTECHNOLOGIES INC | 00773U207 | COM NEW | 18,757 | $40,328 | dollars as filed | |
| BP PRUDHOE BAY RTY TR | 055630107 | TRUS | 77,912 | $39,112 | dollars as filed | |
| SUNCAR TECHNOLOGY GROUP INC | G85727108 | CL A | 14,948 | $38,117 | dollars as filed | |
| OPUS GENETICS INC | 67577R102 | COMMON STOCK | 40,190 | $37,863 | dollars as filed | |
| SMARTRENT INC | 83193G107 | COMMON STOCK | 36,333 | $35,970 | dollars as filed | |
| Arbutus Biopharma Corp | 03879J100 | Common Shares, without par value | 11,299 | $34,914 | dollars as filed | |
| CASTELLUM INC | 14838T204 | COM NEW | 32,996 | $34,646 | dollars as filed | |
| GENERATION BIO CO | 37148K100 | COM | 105,961 | $33,918 | dollars as filed | |
| MARIS TECH LTD | M68057104 | ORDINARY SHARES | 10,558 | $33,786 | dollars as filed | |
| BIOATLA INC | 09077B104 | COM | 82,615 | $32,716 | dollars as filed | |
| ARMLOGI HOLDING CORP | 042255109 | COM | 19,968 | $32,348 | dollars as filed | |
| LITHIUM ARGENTINA AG | H5012F103 | COM SHS | 15,527 | $32,296 | dollars as filed | |
| ARTIVA BIOTHERAPEUTICS INC | 04317A107 | COM | 21,371 | $32,270 | dollars as filed | |
| CELULARITY INC | 151190204 | CL A NEW | 16,204 | $31,760 | dollars as filed | |
| REKOR SYSTEMS INC | 759419104 | COM | 25,680 | $29,789 | dollars as filed | |
| COGNITION THERAPEUTICS INC | 19243B102 | COM | 95,199 | $29,493 | dollars as filed | |
| CORTEXYME INC | 22053A107 | COM | 17,386 | $28,687 | dollars as filed | |
| SMITH MICRO SOFTWARE INC | 832154405 | COM SHS | 30,809 | $26,551 | dollars as filed | |
| CAESARSTONE LTD | M20598104 | ORD SHS | 13,308 | $26,217 | dollars as filed | |
| ITERUM THERAPEUTICS PLC | G6333L200 | COM | 25,245 | $25,119 | dollars as filed | |
| CIBUS INC | 17166A101 | CL A COM STK | 18,163 | $25,065 | dollars as filed | |
| MESA AIR GROUP INC | 590479135 | COM NEW | 26,742 | $24,870 | dollars as filed | |
| GEE GROUP INC | 36165A102 | COM | 123,953 | $24,394 | dollars as filed | |
| MIRA PHARMACEUTICALS INC | 60458C104 | COM | 19,887 | $24,063 | dollars as filed | |
| TRAWS PHARMA INC | 68232V884 | COM NEW | 16,063 | $23,773 | dollars as filed | |
| IMUNON INC | 15117N602 | COM | 29,578 | $23,662 | dollars as filed | |
| DIANA SHIPPING INC | Y2066G104 | COM | 15,900 | $23,214 | dollars as filed | |
| FLY E GROUP INC | 343927109 | COM | 25,305 | $23,015 | dollars as filed | |
| GRYPHON DIGITAL MNG INC | 400510103 | COM | 25,379 | $22,367 | dollars as filed | |
| GOGORO INC | G9491K105 | ORDINARY SHARES | 77,917 | $22,206 | dollars as filed | |
| RALLYBIO CORP | 75120L100 | COM | 63,786 | $21,560 | dollars as filed | |
| HOLLEY INC | 43538H103 | COMMON STOCK | 10,352 | $20,704 | dollars as filed | |
| METAGENOMI THERAPEUTICS INC | 59102M104 | COM | 13,887 | $20,553 | dollars as filed | |
| CITIUS PHARMACEUTICALS INC | 17322U306 | COM | 12,874 | $20,470 | dollars as filed | |
| BRIDGER AEROSPACE GRP HLDGS | 96812F102 | COM | 10,314 | $19,906 | dollars as filed | |
| OSTIN TECHNOLOGY GROUP CO LT | G67927114 | COM | 123,544 | $19,557 | dollars as filed | |
| ENERGOUS CORP | 29272C202 | COM | 70,122 | $19,136 | dollars as filed | |
| PASSAGE BIO INC | 702712100 | COM | 47,156 | $18,877 | dollars as filed | |
| VINCE HLDG CORP | 92719W207 | COM NEW | 13,062 | $18,809 | dollars as filed | |
| CHECHE GROUP INC | G20707108 | CMN | 23,754 | $18,545 | dollars as filed | |
| CAPSTONE HLDG CORP | 14068E208 | CMN | 10,299 | $18,538 | dollars as filed | |
| USIO INC | 917313108 | CMN | 11,732 | $17,950 | dollars as filed | |
| DOCGO INC | 256086109 | COM | 11,339 | $17,802 | dollars as filed | |
| TEN HLDGS INC COM USD0.0001 | 880245105 | Stock | 45,913 | $16,754 | dollars as filed | |
| MAISON SOLUTIONS INC | 560667107 | COM CL A | 18,416 | $16,265 | dollars as filed | |
| WKHS | 98138J404 | Stock | 14,468 | $15,915 | dollars as filed | |
| IOTHREE LTD | G4940T104 | SHS | 37,857 | $15,502 | dollars as filed | |
| HYPERSCALE DATA INC COM SHS | 09175M804 | Stock | 10,691 | $14,967 | dollars as filed | |
| IMPACT BIOMEDICAL INC | 45259L205 | COMMON STOCK | 22,700 | $14,691 | dollars as filed | |
| AGAPE ATP CORP | 008389207 | COM NEW | 11,119 | $14,677 | dollars as filed | |
| LIFEWARD LTD | M8216Q119 | SHS | 20,783 | $13,401 | dollars as filed | |
| ROCKET ONE INC | 44148G204 | COM NEW | 11,099 | $12,986 | dollars as filed | |
| Reviva Pharmaceuticals Holdings Inc | 76152G100 | Common Stock | 28,244 | $10,764 | dollars as filed | |
| EON RESOURCES INC | 40472A102 | COM CL A | 28,851 | $9,971 | dollars as filed | |
| TRINITY BIOTECH INVT LTD | 896438504 | SPONS ADR NEW | 15,073 | $9,797 | dollars as filed | |
| IPOWER INC | 46265P107 | CL A | 14,562 | $9,414 | dollars as filed | |
| DIRECT DIGITAL HOLDINGS INC | 25461T105 | CLASS A COM | 16,054 | $9,071 | dollars as filed | |
| CHECK CAP LTD | M2361E179 | SHS | 11,385 | $8,780 | dollars as filed | |
| DIGIASIA CORP | G27617102 | SHS | 14,459 | $8,250 | dollars as filed | |
| N2OFF INC | 80512Q402 | COM | 35,426 | $8,148 | dollars as filed | |
| VERIFYME INC | 92346X206 | COM NEW | 10,528 | $7,933 | dollars as filed | |
| GRAPHJET TECHNOLOGY | G30449105 | CLASS A ORD SHS | 65,394 | $6,840 | dollars as filed | |
| CYPHERPUNK TECHNOLOGIES INC | 52187K200 | COM NEW | 13,897 | $4,126 | dollars as filed | |
| ADIAL PHARMACEUTICALS INC | 00688A205 | COM NEW | 10,802 | $3,264 | dollars as filed | |
| CROWN LNG HLDGS LTD | G268AP109 | SHS | 22,177 | $1,552 | dollars as filed | |
| HEALTHCARE TRIANGLE INC | 42227W207 | COM NEW | 32,927 | $915 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0000899140-25-000964 | this filing | 2025-08-14 | acceptance time not in the bulk data set |